Effect of intratympanic dexamethasone injection in sudden idiopathic sensorineural hearing loss

Swamy, K. Mallikarjuna; Ganiger, Arati

doi:10.18203/issn.2454-5929.ijohns20163477

Cited by 2 publications

(3 citation statements)

References 21 publications

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“…Swamy et al conducted prospective study on 40 patients to study the effect of intratympanic steroid in patients with SSNHL and found significant improvement of about 50% in hearing loss. 7 In our study the average day of treatment initiation with intratympanic steroid from the onset of hearing loss was two weeks. Zhao et al claim that the treatment which was started within two weeks after the onset of hearing loss is more effective than later.…”

Section: Discussionmentioning

confidence: 65%

“…Intratympanic steroids (ITSs) may treat ISSNHL more effectively than oral steroids. 7 Data to support this hypothesis are limited almost exclusively to case series, which differ in the type of steroid used, the steroid dose, the dose frequency, the method of injection, the existence of previous treatment with oral steroids, and the outcome measurements. Most cases of sudden hearing loss are idiopathic not because they do not have a cause but because we are unable to…”

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confidence: 99%

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Effect of Intratympanic Dexamethasone in Idiopathic Sudden Sensorineural Hearing Loss

Hembrom

Sen

Tamang

et al. 2019

BJOHNS

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Introduction Oral steroids currently represent the standard treatment for idiopathic sudden sensorineural hearing loss The aim of this study is to assess the effectiveness of intratympanic dexamethasone injection for treating ‘Idiopathic sudden sensori-neural hearing loss’ (ISSNHL) not improved with conventional oral steroid. Materials and Methods A prospective study was conducted on 30 patients refractory to oral steroid therapy between June 2017 to May 2018. ‘Intratympanic dexamethasone injection’ (ITDI) was given every week for 3 consecutive weeks. Hearing was assessed by performing pure tone audiogram before every ITDI and also 1 week after the completion of treatment. Results Hearing improvement was found in 19 out of the 30 cases (63.3%). Conclusions Intratympanic dexamethasone significantly improves the prognosis of ISSNHL and is a safe, inexpensive and effective treatment.

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Section: Discussionmentioning

confidence: 65%

mentioning

confidence: 99%

Effect of Intratympanic Dexamethasone in Idiopathic Sudden Sensorineural Hearing Loss

Hembrom

Sen

Tamang

et al. 2019

BJOHNS

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“…Therapy with sudden deafness based on Siegel's criteria was 66.7%. 10,11,12 In this study, there was an improvement in therapy results according to Siegel's criteria, where the most In this study, an analysis was conducted on the relationship between additional systemic steroids and therapy success. A total of 67 samples were given additional systemic steroids.…”

Section: Systemic Steroidmentioning

confidence: 99%

Factors Affecting Intratympanic Corticosteroids Injection Therapy Results in Sudden Deafness Patients at Dr Mohammad Hoesin Hospital Palembang

et al. 2021

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Background. Sudden deafness is an emergency in the Ear Nose Throat Department, a subset of sensorineural hearing loss within a 72-hour window period and consists of a decrease in hearing of 30 decibels affecting at least three consecutive frequencies. The therapy given is corticosteroids, systemic corticosteroids or intratympanic corticosteroids injection, or both. The prognosis of sudden deafness depends on several factors. Patient with sudden hearing loss does not always have the same result in hearing improvement. This study was aimed to determine the factors that affect the results of intratympanic corticosteroid injection therapy in patients with sudden deafness.Methods. This study is an observational study with a cross-sectional design. The data were collected using medical records on 96 ears given intratympanic corticosteroid injection therapy at Dr. Mohammad Hoesin Hospital Palembang from July 2018 to February 2021.Results. From 96 ears conducted in the study, the improvement of therapeutic results on intratympanic corticosteroid injection in patients with sudden deafness was 72.9%. The study found factors that influenced the outcome of therapy, namely age (p=0.002), the onset of therapy (p = 0.003), and the use of a combination of systemic steroids (p=0.010). From the logistic regression test, it was found that the factors that most influenced the results of intratympanic corticosteroid injection therapy were young age 18-40 years (p=0.016) with (OR) 6.654 (CI95% 1.418-31.222) and therapy onset less than two weeks (p=0.027) with (OR) 3.108 (95% CI 1.134-8.515).Conclusions. The factors associated with the improvement in the outcome of intratympanic corticosteroid injection therapy in patients with sudden hearing loss were patient age and early onset of therapy.

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Effect of intratympanic dexamethasone injection in sudden idiopathic sensorineural hearing loss

Cited by 2 publications

References 21 publications

Effect of Intratympanic Dexamethasone in Idiopathic Sudden Sensorineural Hearing Loss

Effect of Intratympanic Dexamethasone in Idiopathic Sudden Sensorineural Hearing Loss

Factors Affecting Intratympanic Corticosteroids Injection Therapy Results in Sudden Deafness Patients at Dr Mohammad Hoesin Hospital Palembang

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