Effect of Intron 3 and Exon 5 Polymorphism in GH1 Gene on Milk Production and Milk Composition Traits in Karan Fries (Holstein Friesian Crossbred) Cattle

Kour, Aneet; Chakravarty, A. K.; Raina, V. S.; Nag, Pranab Kumar

doi:10.5455/ijlr.20180503102023

Cited by 2 publications

(3 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Growth hormone (GH) is produced and secreted by somatotroph cells in the anterior lobe of the pituitary gland in a circadian and pulsatile cycle (Ayuk and Sheppard 2006). GH is a well-studied candidate gene that regulates growth rates and lactation yield traits in several livestock species (Zhou et al 2005;Thomas et al 2007) including goats (Yardibi et al 2009;Kour et al 2018;Amiri et al 2018). Muscle, bone, and adipose tissue are among the target areas that GH has been observed to in uence.…”

Section: Introductionmentioning

confidence: 99%

Genetic polymorphism of the growth hormone gene and their effects on growth metrics in the Assam Hill and Sirohi goats under subtropical climatic condition

Kumar

Kadirvel

Khargharia

et al. 2023

Preprint

View full text Add to dashboard Cite

Growth hormone (GH) is a gene that regulates milk production, reproduction, and growth in animals. Therefore, the purpose of this study was to identify GH gene variations and their associations with growth metrics in Sirohi and Assam hill goats. We identified two polymorphic loci (GH1-HaeIII & GH2-HaeIII) which were connected to growth attributes in 161 animals of Assam hill (n = 114) and Sirohi (n = 47) goats using the methods of PCR-RFLP. According to PCR-RFLP results, the GH gene's GH1-HaeIII locus contains two alleles (A and B) and two genotypes (AA and AB), whereas the GH2-HaeIII locus contains two alleles (C and D) and two genotypes (CC and CD). In the two goat breeds, the allele frequencies of A and B were 0.36 − 0.28 and 0.64–0.72, respectively, while the frequencies of alleles C and D were 0.71 − 0.70 and 0.29–0.30. The polymorphic loci were demonstrated to be in a state of Hardy-Weinberg disequilibrium in both breeds of goats (P < 0.05). The growth characteristics of the Assam hill goat breed were shown to be correlated with GH gene variations. In both breeds, AB and CD genotypes displayed slightly higher values in most of the morphometric traits compared to AA and CC genotypes; however, only in Assam hill goats body length and chest girth were positively significant (P < 0.05). Hence, the AB and CD genotypes have been proposed as potential markers for improved growth parameters in the breeds that were tested. Therefore, we came to the view that the two variant loci of the GH gene will utilize as marker assisted selection for enhancing growth attributes in goats; however, more research with a bigger sample size is necessary to verify the validity of this conclusion.

show abstract

Section: Introductionmentioning

confidence: 99%

Genetic polymorphism of the growth hormone gene and their effects on growth metrics in the Assam Hill and Sirohi goats under subtropical climatic condition

Kumar

Kadirvel

Khargharia

et al. 2023

Preprint

View full text Add to dashboard Cite

show abstract

“…The GH is an anabolic hormone that is synthesized in the anterior pituitary (Ayuk and Sheppard, 2006). It plays a crucial role in physiological regulation, affecting growth, body composition and carcass traits, reproduction, proliferation of mammary cells, and lactogenesis (Yardibi et al, 2009;Kour et al, 2018;Amiri et al, 2018). Due to these crucial biological functions, GH is considered a useful candidate gene for increasing milk and meat yield in buffalo via marker-assisted selection (MAS) programs (Othman et al, 2012).…”

Section: Introductionmentioning

confidence: 99%

“…Three novel polymorphisms have been identified in exon 5 of the GH gene in bovine (Yao et al, 1996). Many studies have been conducted regarding the relationship between GH gene polymorphisms and traits in livestock (Yardibi et al, 2009;Öner et al, 2011;Korkmaz Ağaoğlu and Akyüz, 2013;Akyüz et al, 2013;Akçay et al, 2015;Amiri et al, 2018;Kour et al, 2018;Ozdemir et al, 2018), but limited research was found concerning water buffalo (Andreas et al, 2010;Shi et al, 2012;Othman et al, 2012;Hussain et al, 2014). Andreas et al (2010) identified variation in GH/AluI locus in Indonesian buffalo.…”

Section: Introductionmentioning

confidence: 99%

Identification of novel single nucleotide polymorphisms in the growth hormone ( GH ) gene in Anatolian water buffalo ( Bubalus bubalis ) populations in Turkey

Ünal

Işık

Soysal

2020

Revista Brasileira De Zootecnia

View full text Add to dashboard Cite

Effect of Intron 3 and Exon 5 Polymorphism in GH1 Gene on Milk Production and Milk Composition Traits in Karan Fries (Holstein Friesian Crossbred) Cattle

Cited by 2 publications

References 0 publications

Genetic polymorphism of the growth hormone gene and their effects on growth metrics in the Assam Hill and Sirohi goats under subtropical climatic condition

Genetic polymorphism of the growth hormone gene and their effects on growth metrics in the Assam Hill and Sirohi goats under subtropical climatic condition

Identification of novel single nucleotide polymorphisms in the growth hormone ( GH ) gene in Anatolian water buffalo ( Bubalus bubalis ) populations in Turkey

Contact Info

Product

Resources

About