Effect of iodixanol particle size on the mechanical properties of a PMMA based bone cement

Kjellson, Fred; Abdulghani, Saba; Tanner, K.E.; McCarthy, Ian; Lidgren, Lars

doi:10.1007/s10856-006-0116-8

Cited by 4 publications

(3 citation statements)

References 27 publications

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“…The calculated average tensile strength f t of PMMA bone cement was 43.23MPa. It is located in the range of 33.0 MPa~51.4 MPa for tensile strength f t which has been reported in related literature [17][18][19][20][21]. The average value of fracture toughness K IC was 1.77 MPa • m 1/2 , which likewise falls within the range of 1.0 MPa • m 1/2 ~2.7 MPa • m 1/2 as reported by related literature [10][11][12][13][14][15][16][17].…”

Section: Raw Data Of the Experimentssupporting

confidence: 74%

“…Wedge-splitting specimens (WS) [11,13], three-point bending specimens [10], and chevron-notched short-rod specimens [14][15][16] are commonly used in laboratory testing to examine the fracture parameters of PMMA bone cement. The tensile strength of PMMA bone cement was obtained through four-point bending specimens [19] and dumb-bell specimens [18,21]. A large number of experiments are required to obtain the necessary parameters, which increases costs and the time required for the experiments.…”

Section: A Brief Description Of the Boundary Effect Model (Bem)mentioning

confidence: 99%

“…By transforming Equations ( 16) and ( 17), a simplified prediction model for the tensile strength f t and fracture toughness K IC of PMMA bone cement WS specimens can be obtained. Tensile strength f t = P max /A 1 e and fracture toughness K IC = P max /A 2 e , with respect to the equivalent area A 1 e A 2 e and the peak load P max , can be obtained as shown in Equations ( 18) and (19). Conversely, the peak load P max of the test piece can also be calculated from the equivalent area A 1 e A 2 e and f t (K IC ).…”

Section: Three-parameter Weibull Distribution Prediction Of Pmma Bone...mentioning

confidence: 99%

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A Three-Parameter Weibull Distribution Method to Determine the Fracture Property of PMMA Bone Cement

Cao

Guan

et al. 2022

Polymers

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Poly (methyl methacrylate) (PMMA) bone cement is an excellent biological material for anchoring joint replacements. Tensile strength ft and fracture toughness KIC have a considerable impact on its application and service life. Considering the variability of PMMA bone cement, a three-parameter Weibull distribution method is suggested in the current study to evaluate its tensile strength and fracture toughness distribution. The coefficients of variation for tensile strength and fracture toughness were the minimum when the characteristic crack of PMMA bone cement was αch∗=8dav. Using the simple equation αch∗=8dav and fictitious crack length Δαfic=1.0dav, the mean value μ (= 43.23 MPa), minimum value ftmin (= 26.29 MPa), standard deviation σ (= 6.42 MPa) of tensile strength, and these values of fracture toughness (μ = 1.77 MPa⋅m1/2, KICmin = 1.02 MPa⋅m1/2, σ = 0.2644 MPa⋅m1/2) were determined simultaneously through experimental data from a wedge splitting test. Based on the statistical analysis, the prediction line between peak load Pmax and equivalent area Ae1Ae2 was obtained with 95% reliability. Nearly all experimental data are located within the scope of a 95% confidence interval. Furthermore, relationships were established between tensile strength, fracture toughness, and peak load Pmax. Consequently, it was revealed that peak load might be used to easily obtain PMMA bone cement fracture characteristics. Finally, the critical geometric dimension value of the PMMA bone cement sample with a linear elastic fracture was estimated.

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Section: Raw Data Of the Experimentssupporting

confidence: 74%

Section: A Brief Description Of the Boundary Effect Model (Bem)mentioning

confidence: 99%

Section: Three-parameter Weibull Distribution Prediction Of Pmma Bone...mentioning

confidence: 99%

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A Three-Parameter Weibull Distribution Method to Determine the Fracture Property of PMMA Bone Cement

Cao

Guan

et al. 2022

Polymers

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Mechanical effects, antimicrobial efficacy and cytotoxicity of usnic acid as a biofilm prophylaxis in PMMA

Kim

Greenleaf

Miller

et al. 2011

J Mater Sci: Mater Med

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Experiments were performed to test the null hypothesis that the addition of a natural occurring antibiotic would not alter mechanical properties of polymethylmethacrylate (PMMA). Compression and four-point bending tests were used to assess mechanical properties of zirconium dioxide bearing bone cement (Type Zr) and barium sulfate bearing bone cement (Type Ba), mixed with the antibiotic usnic acid ("usnic"), used to create a surface resistant to biofilm formation. Addition of usnic had a statistically significant effect on the material properties. Compressive and bending strengths decreased as usnic was added and Type Zr was stronger than Type Ba although material properties remained above recommended minima. With implications of liver toxicity with large doses of usnic taken as a dietary supplement, cytotoxicity tests using bone cement coupons were performed and showed very little or no toxicity in primary cultures of rabbit skin derived fibroblasts. A simple test of usnic's efficacy as a biofilm prophylaxis in PMMA was also conducted. Bone cement coupons with usnic were tested for their effectiveness against methicillin resistant Staphylococcus aureus. Diminished biofilm formation on usnic-containing coupons indicated that usnic can be an effective anti-microbial agent.

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Mesoscopic model for the fracture of polymethyl methacrylate bone cement

Guan,

Liu,

et al. 2024

Engineering Fracture Mechanics

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Effect of iodixanol particle size on the mechanical properties of a PMMA based bone cement

Cited by 4 publications

References 27 publications

A Three-Parameter Weibull Distribution Method to Determine the Fracture Property of PMMA Bone Cement

A Three-Parameter Weibull Distribution Method to Determine the Fracture Property of PMMA Bone Cement

Mechanical effects, antimicrobial efficacy and cytotoxicity of usnic acid as a biofilm prophylaxis in PMMA

Mesoscopic model for the fracture of polymethyl methacrylate bone cement

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