“…One hundred and eighteen studies were retrieved, but only full papers in English were taken into consideration. In 76 papers, in vitro experiments were performed by using artificial saliva formulations, in which the following formulas were used most often -artificial saliva according to: (1) Klimek et al [1982], which was the first artificial formula introduced for in vitro studies (differences in mucin content) -17 studies [Attin et al, 1998[Attin et al, , 2000Lennon et al, 2006;Wiegand et al, 2006Wiegand et al, , 2007Magalhaes et al, 2008a;Wiegand et al, 2008aWiegand et al, , 2009aSouza et al, 2010;Wegehaupt and Attin, 2010;Yu et al, 2010a;Levy et al, 2011;Rochel et al, 2011;Magalhaes et al, 2011;Comar et al, 2012;Magalhaes et al, 2012]; (2) Vieira et al [2005] -17 studies [Kato et al, 2007;Magalhaes et al, 2007;Francisconi et al, 2008;Magalhaes et al, 2008b;Kato et al, 2009;Magalhaes et al, 2009;Rios et al, 2009;Bueno et al, 2010;Kato et al, 2010;Magalhaes et al, 2010a, b;Moretto et al, 2010;Barbosa et al, 2011;De Carvalho Filho et al, 2011;Manarelli et al, 2011;Barbosa et al, 2012;Cruz et al, 2012]; (3) Amaechi et al [1998b] -13 studies [Amaechi et al, 1998a…”