Effect of L-Ornithine 8-Vasopressin on Blood Loss During Liposuction

Lalinde, Eugenio; Sanz, José Antonio; Ballesteros, A.; Elejabeitia, Javier; Mesa, Fátima; Bazán, Antonio; Paloma, V.

doi:10.1097/00000637-199506000-00008

Cited by 3 publications

(2 citation statements)

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“… [ 81 , 82 ] Vasoconstrictors Constrict the blood vessels, reduce blood loss, and ameliorate tissue perfusion with the anaesthetics by increasing the duration and the quality of anesthesia. Adrenaline (epinephrine) l -ornithine 8-vasopressin [ [81] , [82] , [83] , [84] ] Local anaesthetics Allow absence of pain sensation during liposuction. Lidocaine Prilocaine Articaine [ [85] , [86] , [87] , [88] ] Buffers Raise the pH of the solution and avoid the burning sensation.…”

Section: Harvestingmentioning

confidence: 99%

Autologous fat grafting: Harvesting techniques

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Brandão

Negrão

et al. 2018

Annals of Medicine and Surgery

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Autologous fat grafting is widely used for soft-tissue augmentation and replacement in reconstructive and aesthetic surgery providing a biocompatible, natural and inexpensive method. Multiple approaches have been developed in the past years, varying in the location of adipose tissue donor-sites, use of wetting solutions, harvesting, processing and placing techniques. Despite many advances in this subject, the lack of standardization in the protocols and the unpredictability of the resorption of the grafted tissue pose a significant limitation for graft retention and subsequent filling. In this review, we discuss several approaches and methods described over the last years concerning the harvesting of autologous fat grafts. We focus on contents such as the best donor-site, differences between existing harvesting techniques (namely tissue resection, hand aspiration or liposuction techniques), recommended harvesting cannula diameters, pressure application and volume of wetting solution injected prior aspiration. Results and comparisons between methods tend to vary according to the outcome measured, thus posing a limitation to pinpoint the most efficient methods to apply in fat grafting. Additionally, the lack of a standard assay to determine viability or volume augmentation of fat grafting remains another limitation to obtain universally accepted grafting procedures and protocols.

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Section: Harvestingmentioning

confidence: 99%

Autologous fat grafting: Harvesting techniques

Fontes

Brandão

Negrão

et al. 2018

Annals of Medicine and Surgery

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“…used l-ornithine 8-vasopressin, instead of epinephrine, at a concentration of 0.01 IU/ml in chilled saline and concluded that blood loss with this technique was less than with conventional epinephrine. [28]…”

Section: Historical Backgroundmentioning

confidence: 99%

Liposuction: Anaesthesia challenges

2011

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Liposuction is one of the most popular treatment modalities in aesthetic surgery with certain unique anaesthetic considerations. Liposuction is often performed as an office procedure. There are four main types of liposuction techniques based on the volume of infiltration or wetting solution injected, viz dry, wet, superwet, and tumescent technique. The tumescent technique is one of the most common liposuction techniques in which large volumes of dilute local anaesthetic (wetting solution) are injected into the fat to facilitate anaesthesia and decrease blood loss. The amount of lignocaine injected may be very large, approximately 35-55 mg/kg, raising concerns regarding local anaesthetic toxicity. Liposuction can be of two types according to the volume of solution aspirated: High volume (>4,000 ml aspirated) or low volume (<4,000 ml aspirated). While small volume liposuction may be done under local/monitored anaesthesia care, large-volume liposuction requires general anaesthesia. As a large volume of wetting solution is injected into the subcutaneous tissue, the intraoperative fluid management has to be carefully titrated along with haemodynamic monitoring and temperature control. Assessment of blood loss is difficult, as it is mixed with the aspirated fat. Since most obese patients opt for liposuction as a quick method to lose weight, all concerns related to obesity need to be addressed in a preoperative evaluation.

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