Effect of lead toxicity on bone calcium content and morphometric parameters

Bhardwaj, Pradeep; Durg, V.

doi:10.18203/2320-6012.ijrms20160027

Cited by 6 publications

(4 citation statements)

References 5 publications

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“…But, no significant changes were observed in length in negative and positive control groups. This result is in the line with (Bhardwaj and Rai, 2016). Table ( 6).…”

Section: Resultssupporting

confidence: 89%

“…The results in the rats in positive control which drinking water contained lead acetate at the amount of (2g/L) had decreased in bone Ca content. The decreasing in Ca concentration may be due to the increase bone resorption (Bhardwaj and Rai, 2016). According, (Ronis et al, 2001) who reported that, the impairment of bone Ca due to the inhibitory action of lead on the osteoblast cells and Vitamin D synthesis for osteocalcin.…”

Section: Resultsmentioning

confidence: 99%

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Effectiveness Protection of Soy Flour and Spirulina on Lead Toxicity

Hassan

El‐Sayed

Salem

2019

Journal of Food and Dairy Sciences

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Lead considered as one of the most risk toxicity of environmental contamination. It causes an increment accumulation in food especially plant food. Also, soy flour is widely used, inexpensive and a highly nutritional source of protein. So, this investigation aimed to study the effect of soy flour (as plant protein source) enriched by spirulina against lead toxicity by using male and female rats. Results: Additional lead acetate in drink water caused a decreasing in hematological tests, blood Fe, Ca and Zn contents. While, spirulina improved status of hemoglobin level and blood Fe content. Whereas, the rats fed on soy flour groups resulted in a high shear force and bone Pb content compared with rats fed on combine with soy flour and Spirulina. Conclusions: Do not depend on plant protein only against lead exposure. Must be combine with animal protein specially milk and milk products.

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“…But, no significant changes were observed in length in negative and positive control groups. This result is in the line with (Bhardwaj and Rai, 2016). Table ( 6).…”

Section: Resultssupporting

confidence: 89%

Section: Resultsmentioning

confidence: 99%

Effectiveness Protection of Soy Flour and Spirulina on Lead Toxicity

Hassan

El‐Sayed

Salem

2019

Journal of Food and Dairy Sciences

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“…It is known that Pb element has many systemic effects and is stored more in the bone in adults (35). In a study on growing rats, it was found to impair bone development (36,37). The result we found is that the Pb element is mostly found and stored in the bone tissue.…”

Section: Mercury (Hg) Evaluationsupporting

confidence: 48%

Comparison of levels of toxic trace elements in two most common spinal pathologies in three different tissues

A.K.,

Yaycioglu,

Daltaban

et al. 2022

roneuro

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Aim: The toxic trace element levels in serum, bone (lamina), and intervertebral disc tissues of patients with lumbar spinal stenosis and lumbar herniated nucleus pulposus (HNP) which are the two most common spinal pathologies were determined, and it was investigated whether they have a role in the pathophysiology of these pathologies. Materials and methods: Cadmium (Cd), aluminium (Al), arsenic (As), mercury (Hg), and lead (Pb) levels in serum, intervertebral disc, and bone (lamina) tissue of patients with HNP (=20) and 30 with lumbar spinal stenosis (LSS) (n=30) were determined by Inductively Coupled Plasma Mass Spectrometry technique. Results: LDH group Cd serum level was found to be significantly higher than LSS group Cd serum level (p=0.024). The Al disc level in the HNP group was found to be significantly higher than the Al disc level in the LSS group (p=0.038). While As serum level increased in LDH group, it was determined that As bone level increased very significantly (r= 0.699, p=0.001). In the LSS group, it was determined that the Hg disc level increased significantly as the Hg serum level increased (r=0.608, p<0.01). On the other hand, as the Hg serum level increased in the LDH group, the Hg disc level also decreased significantly (r= -0.579, p<0.01). Conclusion: The difference in toxic trace element levels seen in these pathologies has been discussed in terms of possible causes in light of current literature. The findings of our study support the hypothesis that toxic trace elements may be effective in lumbar disc degeneration.

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“…Exposure to lead may conduct to numerous human health effects, the brain and kidney being most affected by lead toxicity in both children and adults [93,94]. Even at low concentration, it can induce neurotoxicity (neurobehavioral dysfunctions, deficits in cognition, aggressivity) [95], anaemia [94], cardiac dysfunction and vascular damage [96], nephrotoxicity as lead is eliminated through the kidney [97], male and female reproductive system effects [98], bone toxicity (osteopenia, osteoporosis, osteomalacia) by reduction of bone calcium content [99] and alters the major cellular functions (expression of metabolic enzymes, metallothionein expression, protein kinase activity) [100]. Kidney diseases have been also registered in the investigated areas [53].…”

Section: Leadmentioning

confidence: 99%

Human Health Effects of Heavy Metal Pollution in the Cross-Border Area of Romania and Serbia: A Review

Isvoran

Roman

Dascălu

et al. 2021

Ecological Chemistry and Engineering S

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This review illustrates the state of air, water and soil pollution with heavy metals resulting from mining activities in the cross-border area of Romania and the Republic of Serbia. It also emphasizes the possible human health effects that certain heavy metals can cause. The heavy metals that were identified as polluting the air, water, and/or soil in the area of interest are: As, Cd, Cr, Cu, Fe, Hg, Mn, Mo, Ni, Pb, and Zn. Acute or chronic exposure to these heavy metals may cause numerous human health effects as they affect numerous organs and tissues (gastrointestinal tract, liver, lungs, kidneys, bladder, central nervous system, reproductive system, etc.). The review shows that the pollution produced by both abandoned and active mines cannot be neglected and underlines the necessity of changes in the current mining practices so that mining operations will assure better protection for the environment and human health.

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Effect of lead toxicity on bone calcium content and morphometric parameters

Cited by 6 publications

References 5 publications

Effectiveness Protection of Soy Flour and Spirulina on Lead Toxicity

Effectiveness Protection of Soy Flour and Spirulina on Lead Toxicity

Comparison of levels of toxic trace elements in two most common spinal pathologies in three different tissues

Human Health Effects of Heavy Metal Pollution in the Cross-Border Area of Romania and Serbia: A Review

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