1981
DOI: 10.3382/ps.0601321
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Effect of Levamisole on the Phytohemagglutinin Induced Basophil Hypersensitivity Reaction in the Chicken Wattle

Abstract: The potentiating effect of levamisole (L) on the phytohemagglutinin (PHA) induced hypersensitivity skin reaction in the chicken's wattle was studied. The L increased the number of heterophils and basophils 10 and 6 times, respectively. The number of mononuclear phagocytic cells in the PHA skin reaction was unaltered. These results contrast slightly with those of mammals.

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Cited by 5 publications
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“…It is important to consider that the kinetics and dynamics of basophils in chickens are completely different from those of mammals, these cells have phagocytic properties not found in rodents. 40 This is a classical method to evaluate the activity of T lymphocyte in chickens, 25e27,40,41 since specific monoclonal antibodies subsets against chicken immune cells are available in the market, impairing the use of more specific methods of immune cell counting such as flow cytometry and immuno-histochemistry. The subcutaneous injection of phytohemaglutinin leads to the increase of local skin thickness, peaking at 12 h post challenge.…”
Section: Discussionmentioning
confidence: 99%
“…It is important to consider that the kinetics and dynamics of basophils in chickens are completely different from those of mammals, these cells have phagocytic properties not found in rodents. 40 This is a classical method to evaluate the activity of T lymphocyte in chickens, 25e27,40,41 since specific monoclonal antibodies subsets against chicken immune cells are available in the market, impairing the use of more specific methods of immune cell counting such as flow cytometry and immuno-histochemistry. The subcutaneous injection of phytohemaglutinin leads to the increase of local skin thickness, peaking at 12 h post challenge.…”
Section: Discussionmentioning
confidence: 99%