Effect of ligation of the pacreatic ducts on distribution of endogenous serotonin in organs of the gastrointestinal tract

Shvetsova, O. I.; Lebedev, N. N.

doi:10.1007/bf00806370

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1982

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“…32, 35], In the rabbit, pancreatic duct ligation induces acini involution [10] and Langerhans islets dispersion but do not affect the insulin and glucagon plasma levels, although hyper glycemia develops 20 days after the ligation [14]. Some endocrine cells of the gut are also affected by ligation [33], Directly or indirect ly, these modifications could act on brush border enzyme production.…”

Section: M-mentioning

confidence: 99%

Adaptation of the Activities of the Brush Border Hydrolases along the Small Intestine of the Rabbit after Pancreatic Duct Ligation

Catala¹,

Bonnafous²

1982

Digestion

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The activities of the brush border hydrolases (disaccharidases, α-amylase, γ-amylase, alkaline phosphatase, and aminopeptidases) were determined 2, 6, and 10 weeks after pancreatic duct ligation at 12 different levels of the digestive tract of the rabbit. The activities depended on the nature of the enzyme, on the time elapsed after the ligation, and on the intestinal segment considered. Maltase and γ-amylase activities increased as early as the second week, mainly in the jejunum. Sucrase, trehalase, α-amylase, alkaline phosphatase, and aminopeptidase activities, after a temporary decrease, significantly rose, only from the 10th week on, in an identical manner both in the ileum and the jejunum.

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Section: M-mentioning

confidence: 99%