This study examines the effect of speech level on intelligibility in different reverberation conditions, and explores the potential of loudness-based reverberation parameters proposed by Lee et al. [J. Acoust. Soc. Am., 131(2), 1194-1205 (2012)] to explain the effect of speech level on intelligibility in various reverberation conditions. Listening experiments were performed with three speech levels (L Aeq of 55 dB, 65 dB and 75 dB) and three reverberation conditions (T 20 of 1.0 s, 1.9 s and 4.0 s), and subjects listened to speech stimuli through headphones. Collected subjective data were compared with two conventional speech intelligibility parameters (Speech Intelligibility Index and Speech Transmission Index) and two loudness-based reverberation parameters (EDT N and T N ). Results reveal that the effect of speech level on intelligibility changes with a room's reverberation conditions, and that increased level results in reduced intelligibility in highly reverberant conditions. EDT N and T N explain this finding better than do STI and SII, because they consider many psychoacoustic phenomena important for the modeling of the effect of speech level varying with reverberation.