Effect of mannan-oligosaccharides (MOS) supplementation on performance, immunity and HSP70 gene expression in broiler chicken during hot-dry summer

Abstract

An experiment was conducted on broiler chicks (n=120), reared in cages on a standard diet up to 14 th day of age and thereafter up to 42 nd day (14-42d) on test diets with or without MOS. The 14 th day old chicks were randomly distributed into three dietary treatment groups viz., T 1 (control diet), T 2 (control diet with MOS @ 0.3%) and T 3 (control diet with MOS @ 0.5%). Each dietary treatment comprised of four replicates of eight birds each. Experiment was carried out during hot-dry summer. It was found that production indices improved (P<0.001) significantly during all phases. Cellular and humoral immunity at 28 th day of age improved significantly (P<0.05) due to MOS supplementation. The percentage of hemoglobin, protein, AST and ALT increased significantly (P<0.001) in MOS supplemented group at 28 th as well as 42 nd day of age. While H:L ratio, serum corticosterone and cholesterol levels decreased significantly (P<0.001) in MOS supplemented groups. Supplementation of MOS at the both levels caused significant (P<0.001) down regulation of HSP70 expression in jejunum tissues during 28 th and 42 nd day. Based on this study it was concluded that supplementation of 0.3% MOS in broiler diets significantly improved their performance and welfare during heat stressed conditions.

Impact of dietary Mannan-oligosaccharide and β-Glucan supplementation on growth, histopathology, E-coli colonization and hepatic transcripts of TNF-α and NF- ϰB of broiler challenged with E. coli O78

“…The above results are consonant with those of Mousa et al [17]. Meanwhile, Yalçinkaya et al [21] found a significant decrease in the [22], who found a significant increase in the serum activities of AST and ALT, and protein concentration in broilers dietary supplemented with MOS. These results may be attributed to the antioxidant properties of the MOS, which was reported by Dawood et al [11].…”

“…The colonization of E. coli in the control infected group in different organs showed several rates of 67, 44, 22, 44, and 53% in the respiratory tract, liver, gallbladder, spleen, and fecal swab, respectively (see Table 6). However, in the agrimos infected group, the colonization of E. coli in different organs showed reduced rates of 22,33,22,11, and 33% in the respiratory tract, liver, gallbladder, spleen, and fecal swab, respectively.…”

Impact of dietary Mannan-oligosaccharide and β-Glucan supplementation on growth, histopathology, E-coli colonization and hepatic transcripts of TNF-α and NF- ϰB of broiler challenged with E. coli O78

“…[13] found a significant decreased AST and ALT activities but Rokade et al [14] found significant increased AST and ALT activities and protein concentration of the serum in broilers dietary supplemented with MOS. On the other hand, results of antioxidant enzymes and MDA in harmony with results of Zhou et al [15] who found significant decrease of antioxidant enzymes in birds infected with necrotic enteritis.…”

Assessment of Novel Water Applied Prebiotic to Evaluate Gut Barrier Failure and Performance in Two Commercial Trials in Brazil. A Pilot Study With an Economic Perspective

“…The prebiotic evaluated in the present study is composed of yeast cell wall components (MOS), and fermented Bacillus subtilis components. Dietary supplementation of MOS in poultry diets with or without AGP has been shown to have positive benefits in terms of performance, immune modulation, and reduction of pathogens (37)(38)(39)(40)(41).…”