2022
DOI: 10.1016/j.tjog.2022.01.003
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Effect of maternal hypertensive disorders during pregnancy on offspring's early childhood body weight: A population-based cohort study

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Cited by 2 publications
(2 citation statements)
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“…First, there was a correlation between more significant pro-inflammatory M1/M2 phenotypic skew and adversity during sensitive periods (but not overall life adversity). Second, it has been proven that sepsis in adults and children is related to diminished expression of an immunosuppressive, endotoxin-tolerant phenotype across the lifespan [24][25][26]. Furthermore, this connection remained substantial even after accounting for exposure during a sensitive period.…”
Section: Early Childhood Pregnancymentioning
confidence: 99%
“…First, there was a correlation between more significant pro-inflammatory M1/M2 phenotypic skew and adversity during sensitive periods (but not overall life adversity). Second, it has been proven that sepsis in adults and children is related to diminished expression of an immunosuppressive, endotoxin-tolerant phenotype across the lifespan [24][25][26]. Furthermore, this connection remained substantial even after accounting for exposure during a sensitive period.…”
Section: Early Childhood Pregnancymentioning
confidence: 99%
“…For example, prepregnancy obesity increases risk for child metabolic syndrome or obesity at 4 and 11 y [ 11 , 12 ]. Gestational weight gain (GWG) above the recommended guidelines also increases risk of childhood obesity and overweight, even among individuals with a healthy prepregnancy BMI value [ [13] , [14] , [15] ]. A proposed mechanism for this increased risk is developmental plasticity or fetal programming where the intrauterine environment affects health outcomes during life [ 16 ].…”
Section: Introductionmentioning
confidence: 99%