Effect of medical honey on wounds colonised or infected with MRSA

Blaser, Gisela; Santos, Kai; Bode, Udo; Vetter, H. O.; Simon, Arne

doi:10.12968/jowc.2007.16.8.27851

Cited by 68 publications

(50 citation statements)

References 21 publications

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“…Gamma-irradiated "medical honey" is available, which has also been selected for the potent antibacterial properties, although most of the cases in the medical literature have used raw honey [18,19,38] . Medihoney TM has been one of the first medically certified honeys licensed as medical devices for professional wound care in Europe, the United States (FDA approval) and Australia [31,54] .…”

Section: Discussionmentioning

confidence: 99%

Medical honey and the role in pediatric emergency wound management

Bittmann

Weissenstein²,

Villalon³

et al. 2018

J Pediatr Dis

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The use of complementary medical treatment in wound management has continued to grow throughout the world.There is a large body of evidence to support the use of honey as a wound dressing for a wide range of types of wounds.Clear guidelines for the use of honey in pediatric wound care do not exist. We present an update of present knowledge using honey as a form of complementary medicine in pediatric wound management.

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Section: Discussionmentioning

confidence: 99%

Medical honey and the role in pediatric emergency wound management

Bittmann

Weissenstein²,

Villalon³

et al. 2018

J Pediatr Dis

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“…Our interest for honey is primarily due to their strong activity mainly against Gram-positive bacteria 4,5 . Honey is composed of about 40% fructose, 20% water, amino acids, vitamins (nicotinic acid, pyridoxine, and thiamine), enzymes (diastase, invertase, catalase, and glucose oxidase), hydrogen peroxide, and minerals (potassium, iron, magnesium, phosphorus, copper, zinc and calcium) 13 .…”

Section: Discussionmentioning

confidence: 99%

“…Several alternative therapies have been tested, among which the topical use of substances with high osmolarity 4 , with sugar and its derivatives cited as healing and antimicrobial agents 5,6 .…”

Section: Introductionmentioning

confidence: 99%

Antibacterial properties and healing effects of Melipona scutellaris honey in MRSA-infected wounds of rats

et al. 2016

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PURPOSE:To investigate the antimicrobial, immunological and healing effects of Melipona scutellaris honey on infected wounds of rat skin. METHODS:Twenty four Wistar rats were distributed in four groups (6-each). The uninfected skin wounds of group I rats were treated daily with saline for 7 days. Uninfected wounds (group II) rats were treated with honey. In group III (treated with saline) and group IV (treated with honey) wounds were inoculated with MRSA ATTC43300. The first bacterial culture was performed 24 hours later. In the 7 th day new culture was done, and wound biopsies were used for cytokines dosage and histopathology. RESULTS:In group I and III rats the CFU/g count of S. aureus in wounds was zero. In group II rats the CFU/g counts in the wound tissue were significantly higher than in wounds of group IV rats. The density histopathological parameters and the expression of TNF-α, IL1-β, Il-6 were significantly higher on wounds of group IV then in the other groups.CONCLUSION: Honey of Melipona scutellaris was effective in the management of infected wounds, by significant bacterial growth inhibition, enhancement of cytokine expression, and positively influenced the wound repair.

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“…In a comparative study between ampicillin ointment, saline treatment and honey dressing, honey was the leading antibacterial agent showing least epithelization, inflammation and the most active fibroblastic and angioblastic activity (Gupta, 1992). In a similar observation honey was found to be more active on multidrug resistant bacteria such as methicillin resistant S. aureus (MRSA) than both antibiotics and antiseptics in the treatment of wounds (Blaser et al, 2007a). The results of the hand gel correlate well with Pietsch (2001) allegation when he claimed that alcoholic gels are not always preferable in hand sterilization as they are not compatible with the European standard for hand disinfectants (EN 1500).…”

Section: Pseudomonas Aeruginosamentioning

confidence: 93%

Effects of Selected Wound Dressings and Remedies on Planktonic Bacteria and Bacterial Biofilms of Staphylococcus aureus and Pseudomonas aeruginosa

Alquthami¹

2015

ijSciences

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Abstract:The overall aim of this research is to evaluate the effect of some approaches of treating wounds and the use of wound dressings of on the planktonic bacteria and bacterial biofilms of Staphylococcus aureus and Pseudomonas aeruginosa, two major bacterial species found in wounds. The wound treatments were dressings containing either honey or silver, and commercial hand gels with alcohol. Results indicate that dressings that contain Manuka honey were efficacious against planktonic bacteria of S. aureus, whereas, dressings with silver were most effective against planktonic Pseudomonas aeruginosa. Panaderm (antibiotic) showed the strongest activity against both planktonic S. aureus and P. aeruginosa. The effect of wound treatments on non-established and established bacterial biofilms after 24 and 48 hours after application, show that dressings were effective against the biofilm of S. aureus. However, a non-adherent dressing with Activon Manuka Honey was ineffective against Pseudomonas aeruginosa biofilm. Overall, except for hand gels, the wound remedies tested show remarkable activity against the biofilms of S. aureus and P. aeruginosa.

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Effect of medical honey on wounds colonised or infected with MRSA

Abstract: Full healing was achieved in seven consecutive patients whose wounds were either infected or colonised with methicillin-resistant Staphylococcus aureus. Antiseptics and antibiotics had previously failed to irradicate the clinical signs of infection.

Cited by 68 publications

References 21 publications

Medical honey and the role in pediatric emergency wound management

Medical honey and the role in pediatric emergency wound management

Antibacterial properties and healing effects of Melipona scutellaris honey in MRSA-infected wounds of rats

Effects of Selected Wound Dressings and Remedies on Planktonic Bacteria and Bacterial Biofilms of Staphylococcus aureus and Pseudomonas aeruginosa

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