Effect of Migraine Headache on Productivity of Patients According to Migraine Disability Assessment Score: A Cross-Sectional Study

Jawed, Shafaq; Ali, Waqar; Yaqoob, Uzair; Shah, Shahnaz; Uddin, Syed Mohammad Mazhar; Haq, Aatera

doi:10.1007/s40122-019-0130-4

Cited by 15 publications

(16 citation statements)

References 22 publications

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“…Many studies have confirmed the direct effect of gender on the migraine prevalence, severity, intensity of attacks, and related disabilities, as females were found to have a higher degree in all considerations (7). In our study, migraine-related disabilities were also higher in female migraineurs compared with males.…”

Section: Discussionsupporting

confidence: 85%

“…However, it is the first cause of disability in under 50 years old individuals (19). Migraine-related disabilities include difficulty in doing daily routine activities, a decrease in work performance, and interrupted personal social behaviors (7). In our study, we aimed to clarify the association between migraine disability status, using the MIDAS score, and different personal and social variables.…”

Section: Discussionmentioning

confidence: 99%

“…Most commonly, the first attack of migraine starts in the early years of life (childhood, adolescence, or early adulthood), while most prevalent migraine attacks occur in the third and fourth decades of life (5). Migraine can progress through different stages; prodrome, aura, attack, and post-drome (6), and its symptoms significantly affect the patient's life, productivity, social influence, and professional outcomes (7). Accordingly, migraine is considered as one of the important causes of disability, as noted by the Global Burden of Diseases and the World Health Organization in 2016 (8).…”

Section: Introductionmentioning

confidence: 99%

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Migraine-Related Disabilities Among Saudi Migraine Patients and Its Association with Social Factors

2021

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Background: Migraine is a complex disorder triggered by an interaction of multiple abnormalities involving genes, blood vessels, and brain structures. It is characterized by throbbing headaches, mostly on one side of the head. It is one of the most common causes of disability, as announced by the Global Burden of the Diseases (GBD). Objectives: We aimed at assessing disabilities in Saudi migraine patients and addressing the relation between migraine-associated disabilities and social factors in Saudi Arabia. Methods: We conducted a web-based survey randomly through social media channels to the general population around Saudi Arabia. Basic personal information, along with a confirmation of the migraine diagnosis, were included in the first part of the questionnaire, and the respondent’s eligibility was determined to complete the survey. Specified questions about the sociodemographic characteristics, migraine attacks and medications, and the items of Migraine Disability Assessment score (MIDAS), were included in the next parts of the survey. Results: Of the 480 total responses, 250 (52.1%) eligible participants were included (mean age of 34.84 ± 10.14 years; 83.2% females). Most of the participants were married (59.6%), had three or more kids (50.7%), had a bachelor’s degree (60.8%), and 52.8% were employed. Only 16.4% of the subjects did regular exercise, and 16.8% were current smokers. No significant association was detected between the MIDAS score and most of the social characteristics, including marital status, number of kids, education level, occupation, and smocking. Conclusions: Most of the migraineurs in Saudi Arabia had a severe disability according to the MIDAS score. Gender, regular exercise, the severity of the disease, and frequency of attack had a statistically significant relationship with migraine-related disabilities. Migraine treatment and prophylaxis were incompetent in decreasing migraine severity and related disabilities in our selected participants.

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Section: Discussionsupporting

confidence: 85%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Migraine-Related Disabilities Among Saudi Migraine Patients and Its Association with Social Factors

2021

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“…Secondly, the characteristics of headache were just assessed using HIT-6 and VAS scores in this study. More neuropsychological tests are needed to assess the headache symptom of the migraine, such as the Migraine Disability Assessment Questionnaire (MIDAS) [39] and Visual Light Sensitivity Questionnaire-8 (VLSQ-8) [40]. Furthermore, although we try to diminish the MR scanner noise using earplugs, the tinnitus patients cannot be completely prevented from scanner noise that probably affects the CBF perfusion to varying degree.…”

Section: Discussionmentioning

confidence: 99%

Headache is associated with aberrant cerebral blood flow in chronic tinnitus revealed by perfusion functional MRI

Chen¹,

Hu²,

Cui³

et al. 2020

Preprint

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Background: Chronic tinnitus is often accompanied with headache symptom that will affect the cerebral blood flow (CBF) and exacerbate the tinnitus distress. However, the potential relationship between headache and tinnitus remains unclear. This study will investigate whether aberrant CBF patterns exist in chronic tinnitus patients and examine the influence of headache on CBF alterations in chronic tinnitus. Methods: Participants included chronic tinnitus patients (n=45) and non-tinnitus controls (n=50), matched for age, sex, education, and hearing thresholds. CBF images were collected and analyzed using arterial spin labeling (ASL) perfusion functional magnetic resonance imaging (fMRI). Regions with major CBF differences between tinnitus patients and non-tinnitus controls were first detected. The interaction effects between headache and tinnitus for CBF alterations were further examined. Correlation analyses illustrated the association between CBF values and tinnitus severity as well as between CBF and degree of headache.Results: Compared with non-tinnitus controls, chronic tinnitus patients exhibited decreased CBF, primarily in right superior temporal gyrus (STG), bilateral middle frontal gyrus (MFG), and left superior frontal gyrus (SFG); decreased CBF in these regions was correlated with tinnitus distress. There was a significant interaction effect between headache and tinnitus for CBF in right STG and MFG. Moreover, the degree of headache correlated negatively with CBF in tinnitus patients.Conclusions: Chronic tinnitus patients exhibited reduced CBF in the auditory and prefrontal cortex. Headache may facilitate a CBF decrease in the setting of tinnitus, which may underlie the neuropathological mechanisms of chronic tinnitus comorbid with headache.

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“…Moreover, migraine disability assessment (MIDAS) was used to assess lost days in the past 3 months. It was assessed at the beginning and the end of trial [ 30 ].…”

Section: Methodsmentioning

confidence: 99%

Assessing the Effect of Zinc Supplementation on the Frequency of Migraine Attack, Duration, Severity, Lipid Profile and hs-CRP in Adult Women

et al. 2021

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Migraine is a widespread incapacitating neurologic disorder with debilitating headaches which are usually throbbing due to inefficacy and several side effects, complementary therapies recommended as possible alternatives. The current randomized controlled trial was carried out to evaluate the effect of zinc gluconate supplementation on migraine-related symptoms, serum level of high sensitivity C-reactive protein (hs-CRP) and lipid profile in migraineurs. Present study was designed as randomized double-blind, placebo-controlled trial. Sixty women with migraine (mean age of 35.44 ± 7.42 years ) were randomly allocated to obtain 15 mg per day of zinc gluconate or placebo for 12 weeks. Frequency, periods of headaches and severity of migraine based on numerical rating scale questionnaire and migraine disability assessment (MIDAS) test were checked. Fasting serum level of lipid profile and hs-CRP were assessed at the beginning and the end of trial. Zinc gluconate supplementation significantly reduced the frequency (p = 0.001), periods of migraine attacks (p < 0.001) and severity of migraine and MIDAS (p < 0.001) compared with control group. The serum level of low-density lipoprotein (p < 0.001), total cholesterol (p < 0.001) and hs-CRP (p < 0.001) decreased following zinc supplementation, but no significant differences in serum level of triglycerides (p = 0.1) and high-density lipoprotein (p = 0.3) was observed. However, after adjustment for baseline values using analysis of covariance test, none of lipid profile components and hs-CRP showed a significant difference. Zinc supplementation has beneficial effect on the migraine related complications like its severity, frequency. Trial Registration Iranian Registry of Clinical Trials Identifier: IRCT20191014045100N1

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Effect of Migraine Headache on Productivity of Patients According to Migraine Disability Assessment Score: A Cross-Sectional Study

Cited by 15 publications

References 22 publications

Migraine-Related Disabilities Among Saudi Migraine Patients and Its Association with Social Factors

Migraine-Related Disabilities Among Saudi Migraine Patients and Its Association with Social Factors

Headache is associated with aberrant cerebral blood flow in chronic tinnitus revealed by perfusion functional MRI

Assessing the Effect of Zinc Supplementation on the Frequency of Migraine Attack, Duration, Severity, Lipid Profile and hs-CRP in Adult Women

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