Effect of Mobile Phone Radiation on Cardiovascular Development of Chick Embryo

Abstract

The biological effects on cardiovascular development of chicken embryos were examined after radiation exposure using mobile phone (900 MHz; specific absorption rate˜1.07 W/kg) intermittently 3 h per day during incubation. Samples were selected by morphological and histological methods. The results showed the rate of embryonic mortality and cardiac deformity increased significantly in exposed group (P < 0.05). No any histological pathological changes were observed on Day 5-7 (D5-D7) of incubation. A higher distribution of lipid droplets was unexpectedly present in myocardial tissue from the exposure groups on D10-D13. Soon afterwards, myofilament disruption, atrioventricular valve focal necrosis, mitochondria vacuolization and atrial natriuretic peptide (ANP) decrease appeared on D15-D21 of incubation. Comet assay data showed the haemocyte mean tail in the exposed group was significantly larger than that of the control (P < 0.01). The arterial vascular wall of exposed group was thicker (P < 0.05) than that of the control on D13, which was reversed to normal in later stages. Our findings suggest that long-term exposure of MPR may induce myocardium pathological changes, DNA damage and increased mortality; however, there was little effect on vascular development.

Mobile-phone radiation-induced perturbation of gene-expression profiling, redox equilibrium and sporadic-apoptosis control in the ovary ofDrosophila melanogaster

“…development and increased mortality were observed after radiation exposure of chicken embryos to a mobile phone, intermittently 3 h per day during the incubation period. 51 Tight regulation of oxidative stress represents an essential process for survival and growth of the affected cells. Production or detoxification of ROS, and their downstream transducing signals, and in general redox balance and homeostasis, seem to implicate several transcription factors in humans, with AP-1, FOXOs (3/4), HIF-1a, NRF2, p53 and NF-kB (REL) being the most critical ones.…”

Single-strand DNA breaks and oxidative changes in rat testes exposed to radiofrequency radiation emitted from cellular phones

“…Even though the number of studies on the influence of cellular phones on reproductive functions has increased in recent years, no consensus has been reached. It has been put forth in many studies that exposure to RFR emitted by cellular phones may lead to various negative effects [31][32][33]. Akdag et al [28] examined whether 2.4 GHz (Wi-Fi) RFR causes DNA damage in rats brain, skin, liver, kidney and testicle tissue through the Comet assay method.…”

The Deleterious Effects of Mobile Phone Radiation (900 Mhz) on Behavior Profile of Mice: The Effect of Alternative Therapy in Neuroprotection

“…Many studies reported that mobile phone radiation (MPR) is a highly biological stressor that negatively affect all livestock's health by an oxidative stress (Nazıroğlu et al, 2013), these surrounding electromagnetic radiation (EMR) that compulsorily produced from using of technologies in all fields especially its application and networking even in farm management, subjecting our environment to huge source of EMR which in turn affect human health (Adebayo et al, 2014), domestic animals (Ebrahimi et al, 2018;Everaert and Bauwens, 2007;Hässig et al, 2014), (Wenzel et al, 2002) noted the abnormal behavior in cattle such as lying, pasture and ruminating behaviors as daily behavior profile, also there are the other notable effects recorded in poultry as embryo mortality especially between 9 th and 12 th days of incubation (Batellier et al, 2008), chicks myocardium pathological changes, DNA damage and increased mortality (Ye et al, 2016), these impacted effect also included the wild livestock in form of animal populations decline and deterioration (Balmori, 2009). The biological analyses to these effects explained various effects include anxiety-like behaviors and oxidative stress (Shehu et al, 2016) so a number of studies have concerned to EMR hazards, reported that EMR affects mainly the brain causing neural damage (Hussein et al, 2016), disturbed permeability of blood-brain barrier BBB (Sirav and Seyhan, 2016;Sırav and Seyhan, 2016), affected memory performance (Brzozek et al, 2018), Increasing incidence of the carcinogenic potentiality especially the heart and brain tumors (Falcioni et al, 2018), disturbed urogenital function (Türedi et al, 2017), decreasing the reproductive capacity of both males (Gautam et al, 2019) and females (Shahin et al, 2017), induced hormonal disturbance (Asl et al, 2019;Stephen et al, 2019) and liver damage (Moradpour et al, 2020).…”