2005
DOI: 10.1016/j.colsurfb.2005.07.005
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Effect of molecular weight heterogeneity on drug encapsulation efficiency of gelatin nano-particles

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Cited by 116 publications
(76 citation statements)
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“…NCF3 has the greatest encapsulation efficiency because of smaller particle size and greater surface area. The overall encapsulation efficiency of the N. ciliatus extract in gelatin nanoparticles is 76% and this was significantly higher than the entrapment ratio of conventional gelatin nanoparticles (<45%) as reported by Saxena [50] and Vandervoort [51] and their respective co-workers. Based on these results, it was concluded that gelatin is a suitable carrier for the encapsulation of phytochemical extracts.…”
Section: Characterizationmentioning
confidence: 65%
“…NCF3 has the greatest encapsulation efficiency because of smaller particle size and greater surface area. The overall encapsulation efficiency of the N. ciliatus extract in gelatin nanoparticles is 76% and this was significantly higher than the entrapment ratio of conventional gelatin nanoparticles (<45%) as reported by Saxena [50] and Vandervoort [51] and their respective co-workers. Based on these results, it was concluded that gelatin is a suitable carrier for the encapsulation of phytochemical extracts.…”
Section: Characterizationmentioning
confidence: 65%
“…At the nanoscale level, the physical, chemical, and biological properties of materials fundamentally differ from those at bulk scale. Atomic force microscopy, a nanotechnology tool, has been applied successfully to many fields of food science and technology including imaging of pectin, 3,4 high-purity laboratory-prepared mammalian gelatins, [5][6][7][8][9][10][11] and recently gelatin from fish skin. [12][13][14] The objective of this work was to characterize the nanostructure of food-grade fish gelatin obtained using different preparation conditions and different concentrations.…”
Section: Introductionmentioning
confidence: 99%
“…Gelatin nanoparticles prepared by coacervation method have been witnessed to have a 30-50% loading efficiency for various studied drugs [16][17][18]. Furthermore, gelatin nanoparticles prepared by two step desolvation have shown 7.1-18.5% of loading for cycloheximide [19]. From all the above reports it is apparent that the loading efficiency of gelatin nanoparticles greatly varies.…”
mentioning
confidence: 96%