Effect of molecular weight of PEG or PVA as reducing-stabilizing agent in the green synthesis of silver-nanoparticles

Díaz-Cruz, César; Núñez, Gabriel Alonso; Espinoza-Gómez, Heriberto; Flores-López, Lucı́a Z.

doi:10.1016/j.eurpolymj.2016.08.025

Cited by 52 publications

(23 citation statements)

References 30 publications

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“…Thanks to their intrinsic anticancer activity [ 93 ], AgNPs attracted special attention for this particular domain, and were successfully evaluated as effective anti-tumor drug-delivery systems [ 94 ], acting either as passive [ 95 , 96 ] or active [ 97 , 98 ] nanocarriers for anticancer drugs. For the preparation of biocompatible AgNPs, different strategies were used, such as organic-water two-phase synthesis [ 99 , 100 , 101 ], micro-emulsion [ 102 , 103 , 104 ], radiolysis [ 105 , 106 ], and most commonly, reduction in aqueous solution [ 94 , 107 , 108 ]. Impressive attention, scientific knowledge, and financial support were lately oriented toward the formulation of AgNP-based drug-delivery platforms, thanks to the intrinsic features of nanosilver, including its capacity to bind a wide range of organic molecules, its tunable and strong absorption properties, and its low toxicity [ 109 ].…”

Section: Silver Nanoparticles For Drug-delivery Systemsmentioning

confidence: 99%

Biomedical Applications of Silver Nanoparticles: An Up-to-Date Overview

et al. 2018

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During the past few years, silver nanoparticles (AgNPs) became one of the most investigated and explored nanotechnology-derived nanostructures, given the fact that nanosilver-based materials proved to have interesting, challenging, and promising characteristics suitable for various biomedical applications. Among modern biomedical potential of AgNPs, tremendous interest is oriented toward the therapeutically enhanced personalized healthcare practice. AgNPs proved to have genuine features and impressive potential for the development of novel antimicrobial agents, drug-delivery formulations, detection and diagnosis platforms, biomaterial and medical device coatings, tissue restoration and regeneration materials, complex healthcare condition strategies, and performance-enhanced therapeutic alternatives. Given the impressive biomedical-related potential applications of AgNPs, impressive efforts were undertaken on understanding the intricate mechanisms of their biological interactions and possible toxic effects. Within this review, we focused on the latest data regarding the biomedical use of AgNP-based nanostructures, including aspects related to their potential toxicity, unique physiochemical properties, and biofunctional behaviors, discussing herein the intrinsic anti-inflammatory, antibacterial, antiviral, and antifungal activities of silver-based nanostructures.

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Section: Silver Nanoparticles For Drug-delivery Systemsmentioning

confidence: 99%

Biomedical Applications of Silver Nanoparticles: An Up-to-Date Overview

et al. 2018

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“…Glucose is utilized in reducing silver nitrate into silver nanoparticles in the presence of polyvinyl alcohol (PVA), which reacts as a good host material for metal and semiconductor due to its good thermal stability and chemical resistance [ 18 , 28 ]. PVA is a green and ecofriendly biopolymer because of its water solubility, biocompatibility and non-toxicity, so it is widely used in various biomedical applications [ [29] , [30] , [31] , [32] , [33] ]. Mehrbod et al [ 34 , 35 ] studied the antiviral behavior of AgNPs against influenza virus, and had demonstrated that AgNPs showed a destructive effect on the virus membrane glycoprotein knobs and the cells.…”

Section: Introductionmentioning

confidence: 99%

Preparation of cellulose-based wipes treated with antimicrobial and antiviral silver nanoparticles as novel effective high-performance coronavirus fighter

Hamouda

Ibrahim

Kafafy

et al. 2021

International Journal of Biological Macromolecules

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Coronaviruses (CoV) are a large family of viruses that cause illness ranging from the common cold to more severe diseases such as Middle East Respiratory Syndrome (MERS-CoV) and Severe Acute Respiratory Syndrome (SARS-CoV). We succeeded in preparing disinfectant cellulose-based wipes treated with antimicrobial and antiviral silver nanoparticles to be used for prevention of contamination and transmission of several pathogenic viruses and microbes to human in critical areas such as hospitals and healthcare centers especially coronavirus. In this work, the antimicrobial and antiviral activities of silver nanoparticles (AgNPs) prepared with four different techniques were investigated for the utilization as a disinfectant for cellulose-based wipes. These four methods are namely; 1) trisodium citrate with cotton yarn as a reducing agent, 2) preparing AgNP's using aqueous solution of PVA in the presence of glucose, 3) trisodium citrate with cotton fabric as a reducing agent, and 4) photochemical reaction of polyacrylic acid and silver nitrate solution. Polyester/viscose blended spunlace nonwoven fabrics as cellulose based fabrics were treated with the prepared silver nanoparticles to be used as surfaces disinfection wipes. The properties of the nonwoven fabrics were examined including thickness, tensile strength in dry and wet conditions in both machine direction (MD) and cross-machine direction (CMD), bursting strength, air permeability, water permeability and surface wettability. Characterization of the AgNPs was carried out in terms of UV-VIS spectroscopy, TEM, SEM, and Zeta potential analysis. The assessment of AgNPs active solutions for antimicrobial and antiviral activities was evaluated. The results obtained from the analyses of the AgNPs samples prepared with different techniques showed good uniformity and stability of the particles, as well uniform coating of the AgNPs on the fibers. Additionally, there is a significant effect of the AgNPs preparation method on their disinfectant performance that proved its effectiveness against coronavirus (MERS-CoV), S. aureus and B. subtilis as Gram-positive bacteria, E. coli and P. mirabilis as Gram-negative bacteria, A. niger and C. albicans fungi.

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“…Elas estão presentes em produtos na indústria de alimentos, têxtil, perfumaria, farmacêutica, agrícola, higiene, produtos de limpeza, tintas, eletroeletrônicos, entre outras. [7][8][9][10][11][12][13][14][15][16][17] Possuem uma ampla aplicabilidade, como por exemplo, em medicina, cosmetologia, no recobrimento de dispositivos médicos, na confecção de nanogéis, nanoloções, na preparação de materiais para recobrimento de lesões cutâneas. [11][12][13][14] Importância das NPs de Ag na pesquisa e no mercado Ao se realizar uma busca em plataformas de busca de artigos científicos, como o Web of Science -ISI, pode-se encontrar numerosas citações em função de vários parâmetros.…”

Section: O Que São Nanopartículasde Prata (Nps De Ag)?unclassified

“…22 Além disso, a síntese química também apresenta versatilidade e outros agentes redutores utilizados são o poli (álcoolvinílico) (PVA) e poli (etilenoglicol) (PEG), polímeros biocompatíveis que também atuam como agente estabilizantes. 11,23 Em geral, a síntese química forma NPs de Ag com considerável reprodutibilidade, permitindo o controle do tamanho e dispersão das nanopartículas, controlando os parâmetros experimentais. Destaca-se que a síntese química permite o maior controle do tamanho das NPs obtidas.…”

Section: Rotas De Síntese De Nps De Agunclassified

Nanotoxicologia De Nanopartículas De Prata: Toxicidade Em Animais E Humanos

et al. 2018

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NANOTOXICOLOGY OF SILVER NANOPARTICLES: TOXICITY IN ANINALS AND HUMANS. Silver nanoparticles (AgNPs) have important antimicrobial activity. These nanoparticles are present in several commercial products, leading to human and environmental exposure. This review presents a critical view of the toxic effects of Ag NPs on in vitro and in vivo biological models. It is noteworthy that the toxicity of AgNPs is dependent on several parameters, such as the preparation mode of the colloidal suspension of the nanoparticles, their state of aggregation, the chemical nature of the nanoparticles, surface size, morphology, dose, cell type, nature of the living organism, among others. In general, low concentrations of AgNPs do not present significant toxicity in in vitro and in vivo assays, however with the increase of the concentration of AgNPs there is a significant increase of nanoparticle toxicity and its accumulation in diverse tissues/organs. It should be emphasized that in living organisms, exposure routes should be taken into account, such as ingestion and inhalation. At high concentrations, inhalation or ingestion of AgNPs can cause adverse effects and even lead to human death. In this context, the importance of further studies of the toxicity of AgNPs in several in vitro and in vivo models is emphasized.

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Effect of molecular weight of PEG or PVA as reducing-stabilizing agent in the green synthesis of silver-nanoparticles

Cited by 52 publications

References 30 publications

Biomedical Applications of Silver Nanoparticles: An Up-to-Date Overview

Biomedical Applications of Silver Nanoparticles: An Up-to-Date Overview

Preparation of cellulose-based wipes treated with antimicrobial and antiviral silver nanoparticles as novel effective high-performance coronavirus fighter

Nanotoxicologia De Nanopartículas De Prata: Toxicidade Em Animais E Humanos

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