Effect of Moringa oleifera on hematological parameters of calves reared in industrial fluorotic area

Abstract

Aim:The present study was undertaken to evaluate the ameliorative potential of dried Moringa oleifera fruit powder in fluorosis affected calves reared around the vicinity of aluminium smelter plant.Materials and Methods:Total 107 calves were screened on the basis of clinical signs and higher plasma fluoride (more than 0.2 ppm) level for evidence of fluorosis. Out of that, 90 samples found positive and from them 18 calves of 6-12 months age group were selected and divided equally into three groups named as Group II, III, and IV. Group II remained as disease control group whereas Group III calves were supplemented with dried M. oleifera fruit powder of 25 g/calve for 60 days. Group IV calves were supplemented with calcium carbonate at 100 mg/kg body weight and boric acid at 10 mg/kg for the same experimental period. Group I consisted of six numbers of healthy calves taken from the non-fluorotic zone, i.e. Bhubaneswar. Plasma fluoride level, hemoglobin (Hb), packed cell volume (PCV), total leukocyte count (TLC), differential count (DC), total erythrocyte count, mean corpuscular volume (MCV), mean corpuscular Hb (MCH), and MCH concentration (MCHC) were estimated on day 0, 30, and 60 of the experiment.Results:Supplementation of dried M. oleifera fruit powder to fluorosis affected calves resulted in significant reduction in plasma fluoride level and increase in Hb%, PCV, TLC and altered DC. Similar results were also recorded in calcium+boron group, except PCV and Hb. No significant changes were observed in MCV, MCH, and MCHC values.Conclusion:The present study concluded that supplementation of dried M. oleifera fruit powder daily for 60 days has shown protection against chronic fluoride toxicity in calves.

Haematological evaluation of sodium fluoride toxicity in oryctolagus cunniculus

“…The increase in the clotting time may be due to the fact that NaF is an anticoagulant and also chelates calcium ions from the blood, which is pre-requisite for blood clotting. Similar findings have been reported in buffalo calves [51] , [52] .…”

Comparative Ameliorative Efficacy of Tamarind Pulp against Boron on Fluorotic Calves Reared in Periphery Villages of Aluminium Smelter Plant

“…But more significant increase in the above parameter along with TLC in tamarind supplementation group might be due to high iron and antioxidant like polyphenols and flavanoids, reported to be present in tamarind (Martinello et al, 2006). Similar reports of improved haematological parameters was also reported by Mandal et al, (2015) after feeding of Moringa oleifera fruit powder in fluorotic calves due to reduced fluoride load in plasma.…”

“…The presence of anemia in F-affected animals was also reported in calves (Bharti et al, 2007), buffaloes (Swarup and Singh 1989) and cows Swarup 1994 andMandal et al, 2015) whereas decrease in TLC was previously observed by Behera (1993) and Swarup and Singh (1989) in cattle. On the contrary, leucocytosis was observed in Finduced buffalo calves by Gill and Dumka (2013).…”

Moringa olifera: constituents and protective effects on organ systems

“…The usage of MO is known to have positive effects on some hematological parameters. This could be due to the phytochemical constituents in the extract and also presence of minerals and vitamins (Mandal et al, 2015). These constituents are well-known haemopoietic factors that have direct influence on the production of blood cells in the bone marrow.…”