2017
DOI: 10.1186/s12872-017-0604-4
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Effect of neuroticism on risk of cardiovascular disease in depressed persons - a Swedish population-based cohort study

Abstract: BackgroundThe relationship between neuroticism, depression and cardiovascular disease (CVD) is complex and has so far not been studied in depth. The aim of this study was to determine if neuroticism is an effect-modifier in the association between depression and CVD. Data derived from a longitudinal cohort study on mental health, work and relations among adults (20–64 years), including 10,443 individuals. Depression was assessed using the Major Depression Inventory (MDI) and neuroticism by the Swedish Scale of… Show more

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Cited by 30 publications
(27 citation statements)
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“…More than 300 million people globally suffer from major depressive disorder (MDD) and it is ranked as the leading cause of disability worldwide by the World Health Organization in 2017. In addition, studies have also suggested a link between neuroticism and poor cardiovascular outcomes (Almas, Moller, Iqbal, & Forsell, 2017). A booklength review on this subject was given in Baune and Tully (2016).…”
Section: Introductionmentioning
confidence: 99%
“…More than 300 million people globally suffer from major depressive disorder (MDD) and it is ranked as the leading cause of disability worldwide by the World Health Organization in 2017. In addition, studies have also suggested a link between neuroticism and poor cardiovascular outcomes (Almas, Moller, Iqbal, & Forsell, 2017). A booklength review on this subject was given in Baune and Tully (2016).…”
Section: Introductionmentioning
confidence: 99%
“…A book-length review on this subject was given in Baune and Tully 5 . In addition, studies have also suggested a link between neuroticism and poor cardiovascular outcomes 6,7 . However, the mechanism underlying the relationship between depression and cardiometabolic traits is not well understood.…”
Section: Introductionmentioning
confidence: 99%
“…The discussion between the relationship between personality factors and cardiovascular disease can be said to be a hot topic [34][35][36]. Our study found that open personality can be used as a protective factor for the risk of cardiovascular disease in diabetic patients.…”
Section: Discussionmentioning
confidence: 65%