Effect of Novel Quercetin Titanium Dioxide-Decorated Multi-Walled Carbon Nanotubes Nanocomposite on Bacillus subtilis Biofilm Development

Abstract

The present work was targeted to design a surface against cell seeding and adhering of bacteria, Bacillus subtilis. A multi-walled carbon nanotube/titanium dioxide nano-power was produced via simple mixing of carbon nanotube and titanium dioxide nanoparticles during the sol-gel process followed by heat treatment. Successfully, quercetin was immobilized on the nanocomposite via physical adsorption to form a quercetin/multi-walled carbon nanotube/titanium dioxide nanocomposite. The adhesion of bacteria on the coated-slides was verified after 24 h using confocal laser-scanning microscopy. Results indicated that the quercetin/multi-walled carbon nanotube/titanium dioxide nanocomposite had more negativity and higher recovery by glass surfaces than its counterpart. Moreover, coating surfaces with the quercetin-modified nanocomposite lowered both hydrophilicity and surface-attached bacteria compared to surfaces coated with the multi-walled carbon nanotubes/titanium dioxide nanocomposite.

Recent advances in nanodentistry: a special focus on endodontics

“…Hydrophobic properties and a positive charge of QPEI increase its antibacterial activity [47]. Adding titanium dioxide NPs also prevents microorganism adhesion and biofilm formation by increasing the hydrophilic activity of materials [48]. Silica NPs could also increase the flexural strength, thermal and strength stability of materials [49] Gerasymchuk et al confirmed the antimicrobial activity of graphite oxide‐based composite containing silver NPs.…”

Antibacterial Properties of a Novel Zirconium Phosphate-Glycinediphosphonate Loaded with Either Zinc or Silver

“…The efforts made to develop successful coatings which are capable of warding off implant infections have multiplied over the years [10,11,12]. In view of the decreasing efficacy of antibiotic substances against populations of bacteria which are increasingly drug-resistant, attention has been directed toward alternative antibacterial bioactive principles, including disinfectant molecules [13,14], metal ions and nanoparticles [15], nanocomposites [16], phytochemicals [17], and antimicrobial peptides [18].…”

Zirconium Carboxyaminophosphonate Nanosheets as Support for Ag Nanoparticles

“…Moreover, anti-infective properties have been conferred to implants by immobilizing on their surface active metals, nitric oxide (NO)-releasing materials, or non-antibiotic antibacterial substances in order to avoid the development of multiresistant bacterial strains [11]. Nanotechnology is opening up new frontiers in the design of anti-infective surfaces [12,13,14,15]. The application of metals and metal oxides, such as Ag, Au and ZnO, in the form of nanometric-sized particles as antimicrobial coatings is steadily increasing due to a series of distinctive features of such nanomaterials, including a high surface area and chemical reactivity, which allows high bioactivity, even in small doses [16].…”