Effect of organized media on the chromatographic and electrophoretic determination of pharmaceutical preparations in biological samples

Карцова, Л. А.; Стрельникова, Е. Г.

doi:10.1134/s1061934809020117

Cited by 5 publications

(4 citation statements)

References 18 publications

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“…Besides, it is known that the addition of β‐CD into the BGE is used for the separation of neutral hydrophobic analytes (e.g. steroids ) due to formation of guest‐host complexes or for enantioselective separation . Thus, the covalent coating based on imidazolium cation and β‐CD can provide both the CZE and the CEC mode and, in turns, separation of various analytes.…”

Section: Resultsmentioning

confidence: 99%

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Multifunction covalent coatings for separation of amino acids, biogenic amines, steroid hormones, and ketoprofen enantiomers by capillary electrophoresis and capillary electrochromatography

Кравченко

Колобова

Карцова

2020

Separation Science Plus

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In this study, the preparation process of multifunctional coating based on imidazole and β-cyclodextrin has been developed. The synthesis includes several steps: activation of fused silica capillary walls via alkali, then process of silylation and finally functionalization with imidazole and β-cyclodextrin derivative. The latter step was carried over 22 h at 100 • C at 750 mg/mL concentration of p-toluenesulfonyl-β-cyclodextrin.It was established that the coatings thus obtained are stable within pH 2-7 range but decompose in alkaline medium. The stationary phase developed in this study allows simultaneous separation of hydrophobic and hydrophilic analytes. Chiral separation of ketoprofen enantiomers was also achieved with the newly developed covalent coating.It was found that covalent coating based on imidazole and β-cyclodextrin exceeded the dynamic coatings of similar structure in terms of repeatability, analysis time and the limits of detection.

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Section: Resultsmentioning

confidence: 99%

“…The latter was synthesized from Ts‐β‐CD that was obtained previously (2.3.2.) . At first, the inner surface of the fused silica capillary was activated: the flushing for 2 h with 2 M NaOH solution, 5 min with distilled water, 10 min with 0.1 M HCl solution and again for 5 min with distilled water.…”

Section: Methodsmentioning

confidence: 99%

Multifunction covalent coatings for separation of amino acids, biogenic amines, steroid hormones, and ketoprofen enantiomers by capillary electrophoresis and capillary electrochromatography

Кравченко

Колобова

Карцова

2020

Separation Science Plus

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“…Steroid hormones, i.e., progesterone, 11 desoxycortisol, 17 hydroxyprogsterone, 11 des oxycorticosterone, corticosterone, 11 dehydrocorti costerone, cortisone, and cortisol, are hydrophobic non ionogenic compounds. So, micellar electroki netic chromatography was adopted as a method of their electrophoretic determination [16,17].…”

Section: Resultsmentioning

confidence: 99%

“…On line preconcentration was performed by sweeping upon addition of 5 mM of β cyclodextrin to the sample solution. The detection limit was approximately 5 ng/mL [16,17].…”

Section: Methodsmentioning

confidence: 99%

Different methods of on-line preconcentration in the electrophoretic determination of amines, amino acids, and steroid hormones

Карцова

Sidorova²,

Бессонова

2012

J Anal Chem

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Abstracts-The scope and limitations of various types of on line preconcentration for ionogenic and neutral analytes, i.e., catecholamines, amino acids and, steroid hormones, under the conditions of capillary zone electrophoresis and micellar electrokinetic chromatography are examined. The preconcentration factors of the studied analytes were found to be influenced by pH of the buffer solution and the origin and composition of the samples.

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Functional supramolecular systems: design and applications

et al. 2021

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The interest in functional supramolecular systems for the design of innovative materials and technologies, able to fundamentally change the world, is growing at a high pace. The huge array of publications that appeared in recent years in the global literature calls for systematization of the structural trends inherent in the formation of these systems revealed at different molecular platforms and practically useful properties they exhibit. The attention is concentrated on the topics related to functional supramolecular systems that are actively explored in institutes and universities of Russia in the last 10–15 years, such as the chemistry of host–guest complexes, crystal engineering, self-assembly and self-organization in solutions and at interfaces, biomimetics and molecular machines and devices. The bibliography includes 1714 references.

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Effect of organized media on the chromatographic and electrophoretic determination of pharmaceutical preparations in biological samples

Cited by 5 publications

References 18 publications

Multifunction covalent coatings for separation of amino acids, biogenic amines, steroid hormones, and ketoprofen enantiomers by capillary electrophoresis and capillary electrochromatography

Multifunction covalent coatings for separation of amino acids, biogenic amines, steroid hormones, and ketoprofen enantiomers by capillary electrophoresis and capillary electrochromatography

Different methods of on-line preconcentration in the electrophoretic determination of amines, amino acids, and steroid hormones

Functional supramolecular systems: design and applications

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