Effect of patient sex on general anaesthesia and recovery

Buchanan, Frank F; Myles, Paul S.; Cicuttini, Flavia Maria

doi:10.1093/bja/aer094

Cited by 133 publications

(114 citation statements)

References 39 publications

(22 reference statements)

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“…3,9,15 There was no correlation between age and PQR, which is consistent with other studies. 9 This finding may be explained by the fact that elder patients tend to positively evaluate their health status and attribute less relevance to pain, nausea and vomiting.…”

Section: Discussionsupporting

confidence: 91%

Quality of Recovery after Anesthesia: Validation of the Portuguese Version of the “Quality of Recovery 15” Questionnaire

et al. 2015

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Background:The "Quality of Recovery 15" questionnaire is used for the study of quality recovery after anesthesia. The aim of this study was to validate the Portuguese version of "Quality of Recovery 15" questionnaire. Material and Methods:After study approval by the institutional ethics committee, an observational and cohort prospective study was conducted on patients scheduled for elective surgery from June to August 2013. The "Quality of Recovery 15" questionnaire was translated in accordance with available guidelines. The "Quality of Recovery 15" Portuguese version was used before surgery (T0) and 24h postoperatively (T1) on 170 patients. Patients who were unable to give informed consent or had cognitive impairment were excluded. Poor quality of recovery was defined for "Quality of Recovery 15" score at T1 lower than the mean "Quality of Recovery 15" score minus 1 standard deviation. Reliability and observer disagreement was assessed using interclass correlation. Non-parametric tests were used for comparisons.Results: There was a negative correlation between "Quality of Recovery 15" score and time spent in the postanesthesia care (ρ = −0.264, p = 0.004) and length of hospital stay (ρ = −0.274, p = 0.004). Thirty-two patients (19%) had poor quality of recovery. Patients with poor quality of recovery had more frequently diabetes mellitus and hypertension and they were taking antidepressants drugs more frequently. Patients with poor quality of recovery were more frequently submitted to combined anesthesia and less frequently to general anesthesia and locoregional anesthesia (p = 0.008). The questionnaire had a good internal consistency and test-retest reliability was good. Discussion: The Portuguese version of the "Quality of Recovery 15" showed a good correlation with the original. Conclusion:This questionnaire appears to be an accurate and reliable assessment for quality of recovery.

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Section: Discussionsupporting

confidence: 91%

Quality of Recovery after Anesthesia: Validation of the Portuguese Version of the “Quality of Recovery 15” Questionnaire

et al. 2015

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“…Women emerged faster from general anaesthesia but their overall quality of recovery was poorer. Female sex hormones, particularly progesterone, might be involved, with premenopausal women having faster recovery time but poor overall recovery [20].…”

Section: Resultsmentioning

confidence: 99%

Influences of Gender on Postoperative Morphine Consumption

Periasamy

Poovathai

Pondiyadanar

2014

JCDR

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“…A study by Buchanan et al [13] found that with the same anesthetic protocol for general anesthesia women recovered earlier than men; however women felt more pain in the recovery room and stayed there for longer. Whitley et al [14] stated that this may be due to differences in the pharmacodynamics of women.…”

Section: Discussionmentioning

confidence: 99%

The effect of gender on reversal of non-depolarizing block with Sugammadex

Öztürk¹,

Pişkin²,

Küçükosman³

et al. 2017

Med-Science

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Sugammadex is a rapid and selective aminosteroid agent that has entered use recently. We aimed to research the effect of gender on reversal of non-depolarizing block with sugammadex. We designed a prospective study. The research included a total of 100 cases who underwent rhinoplasty operation administered general anaesthesia. Cases were divided according to gender as male (Group M) and female (Group F). At the end of the operation for patients with TOF value 25%, patients were given 2 mg kg-1 iv sugammadex. Duration from the rocuronium administration until the TOF value was zero(TOF0), the time from sugammadex administration until TOF reached from 25% to 90% was recorded (TOF25-90). The time from TOF90 to extubation was named the extubation duration. From the time the patients entered the PCU until Aldrete score was ≥9 was named the recovery duration and recorded. The time for the groups to TOF25-90 was 123.84 ± 38.03 s in Group M and 122.06 ± 30.461 s in Group F (p > 0.05). The extubation duration was 189.68 ± 41.37 s in Group M and 206.50 ± 45.99 in Group F (p = 0.316). The recovery time was 8.26 ± 14 min in Group M and 8.48 ± 14.23 min in Group F (p = 0.328). After the administration of sugammadex, there was no difference observed between the groups in terms of the TOF25-90 duration, recovery and extubation duration. As a result, conclusion was reached that gender did not affect rocuronium reversal with sugammadex.

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Effect of patient sex on general anaesthesia and recovery

Cited by 133 publications

References 39 publications

Quality of Recovery after Anesthesia: Validation of the Portuguese Version of the “Quality of Recovery 15” Questionnaire

Quality of Recovery after Anesthesia: Validation of the Portuguese Version of the “Quality of Recovery 15” Questionnaire

Influences of Gender on Postoperative Morphine Consumption

The effect of gender on reversal of non-depolarizing block with Sugammadex

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