Effect of Peaches, Pears and Green Tea on Plasma Lipids Profile and Antioxidant Content in Rats Fed High Sucrose Diet

Abstract

The beneficial effects of feeding syrup of peaches and pears (peel and pulp) & green tea on the restoration of the changes produced by feeding high sucrose diet on plasma lipid profile, plasma antioxidant activity, and antioxidant enzymes in red blood cells (RBC) hemolysate were studied. High sucrose diet induced hyperlipidemia as manifested by significant (P ≤ 0.05) increases in the levels of cholesterol, triglycerides (TG) and low density lipoproteins (LDL) in plasma from 103.33 ± 1.8, 61.17 ± 0.48 and 26.6 ± 5.01 mg/dl to 136.67 ± 2.2, 81.3 ± 1.5 and 64.6 ± 6.5 mg/dl respectively. The high density lipoproteins (HDL) level was not significantly affected. TG levels in heart muscles increased significantly P ≤ 0.05 from the level of 194.14 ± 4.35 µg/g in the negative control to 269.72 ± 5.39 µg/g. Administration of fruits syrup and green tea resulted in a significant variable reduction in the elevated levels of cholesterol, TG and LDL and TG in the heart. Administration of sucrose resulted also in elevation of Malondialdehyde ( 894the levels of plasma cholesterol, TG and heart TG levels. The activities of SOD and GSH-Px were increased following the treatment. It can be concluded that syrup of peaches and pears (peel and pulp) & green tea modulate lipid metabolism and enhance antioxidant status and in this respect green tea produced the best effect followed by peels of pears and peaches. The beneficial effect produced by fruits syrup and green tea may be due to their contents of phytochemicals.

Protective Effect of Sweet Potato Peel against Oxidative Stress in Hyperlipidemic Albino Rats

“…Feeding high fat diet resulted in histopathological changes in the liver tissues and that may be due to liberation of lipid peroxides that may cause damage to the cell membrane and making the membrane fragile [36] and [37]. However, feeding in fermented milk containing SPPE showed sign of recovery liver cells from acute cell swelling, edema, dilation and congestion of blood vessels and sinusoids.…”

Efektifitas Pemberian Jus Tomat Dan Jambu Biji Merah Terhadap Penurunan Kolesterol Total Pada Wanita Overweight

“…Banyaknya kandungan serat kasar terlarut, terutama pektin, menjadikan jambu biji bersifat hipokolesterolemik dan hipoglikemik yang dapat menurunkan kadar kolesterol darah. [19][20][21] Mekanisme pektin dalam menurunkan kadar kolesterol yaitu dengan cara menunda pengosongan lambung yang dapat membatasi asupan kalori yang masuk, meningkatkan ketebalan lapisan intestinal yang berfungsi sebagai tempat absorpsi lipid, memberikan efek hipomotilitas untuk memperlambat proses pencernaan dan absorpsi zat gizi, serta serat mengikat asam empedu melalui siklus enterohepatik yang merupakan produk akhir dari kolesterol dan kemudian di usus serat akan difermentasi bakteri bakteri untuk memproduksi asamasetat propionate dan butirat yang berfungsi untuk menghambat sintesis kolesterol, akibatnya cairan empedu ini akan terus ke usus besar untuk disekresikan bersama feses. Hal tersebut dapat menyebabkan terjadinya penurunan kadar kolesterol di dalam tubuh.…”