Effect of Photobiomodulation Therapy on Peri-Implant Bone Healing in Extra-Short Implants in a Rabbit Model: A Pilot Study

Kuzu, Turan Emre; ÖZTÜRK, Kübra; Gürgan, Cem A.; Üşümez, Aslıhan; Yay, Arzu; Göktepe, Özge

doi:10.1089/photob.2021.0098

Cited by 2 publications

(1 citation statement)

References 54 publications

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“…[282] In recent years, researchers found that medications, and especially host modulators, show great potential in resolving or inhibiting the periodontal inflammatory process, particularly in the early phases of periodontitis combined with nonsurgical periodontal treatment. [283][284][285][286][287][288][289] These host modulators include statins like atorvastatin, rosuvastatin, and simvastatin, as well as alendronate and metformin. [80,89,92,95,96,98,99,105,[290][291][292][293][294][295][296] Statins exhibit anti-inflammatory and immunomodulatory properties while inhibiting osteoclasts and stimulating bone morphogenetic proteins.…”

Section: Future Of Periodontal Regenerationmentioning

confidence: 99%

From Basic Science to Clinical Practice: A Review of Current Periodontal/Mucogingival Regenerative Biomaterials

De Lauretis,

Øvrebø,

Romandini

et al. 2024

Advanced Science

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Periodontitis is a dysbiosis‐driven inflammatory disease affecting the tooth‐supporting tissues, characterized by their progressive resorption, which can ultimately lead to tooth loss. A step‐wise therapeutic approach is employed for periodontitis. After an initial behavioral and non‐surgical phase, intra‐bony or furcation defects may be amenable to regenerative procedures. This review discusses the regenerative technologies employed for periodontal regeneration, highlighting the current limitations and future research areas. The search, performed on the MEDLINE database, has identified the available biomaterials, including biologicals (autologous platelet concentrates, hydrogels), bone grafts (pure or putty), and membranes. Biologicals and bone grafts have been critically analyzed in terms of composition, mechanism of action, and clinical applications. Although a certain degree of periodontal regeneration is predictable in intra‐bony and class II furcation defects, complete defect closure is hardly achieved. Moreover, treating class III furcation defects remains challenging. The key properties required for functional regeneration are discussed, and none of the commercially available biomaterials possess all the ideal characteristics. Therefore, research is needed to promote the advancement of more effective and targeted regenerative therapies for periodontitis. Lastly, improving the design and reporting of clinical studies is suggested by strictly adhering to the Consolidated Standards of Reporting Trials (CONSORT) 2010 statement.

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