Effect of Platelet‐Rich Plasma on the Healing of Intrabony Defects Treated With Beta Tricalcium Phosphate and Expanded Polytetrafluoroethylene Membranes

Dőri, Ferenc; Húszár, Tamás; Nikolidakis, Dimitris; Tihanyi, Dóra Krisztina; Horváth, Attila; Arweiler, Nicole Birgit; Gera, István; Sculean, Anton

doi:10.1902/jop.2008.070473

Cited by 80 publications

(69 citation statements)

References 49 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Similar results on comparison between two groups were obtained in previous studies [23,24,[31][32][33][34], but contradictory results were found by Saini N et al, (2011), where there was significant reduction in PPD in test group compared to control group [35].…”

Section: Discussionsupporting

confidence: 86%

“…Till date, there are no studies on PRP combined with Biograft-HT. However, the results of our study compare favorably with other studies with PRP combined with other alloplasts [23] and bovine porous bone mineral [30,31].…”

Section: Discussionsupporting

confidence: 80%

“…But when the local conditions are not optimum, PRP gels alone are not strong enough to promote a clinical filling equivalent to the dense bone filling reached with a bone substitute [50]. Most of the randomized controlled clinical trials(RCTs) demonstrated that the addition of PRP to certain regenerative materials, doi: 10.7243/2050-1218-2-11 namely bioactive glass [51], b-TCP [52], BM and e-PTFE membranes [53], b-TCP and e-PTFE membranes [54], BM and collagen membranes [23] and BM and EMD [55], failed to confer statistically significant additive benefits in the therapy of periodontal intraosseous defects. However, according to other RCTs such adjunctive positive outcomes may result from other combinations of PRP, namely together with BM [28], DFDBA [56] and hydroxyapatite [22].…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

A clinical and radiographic evaluation of the management of periodontal osseous defects with alloplast and platelet rich plasma

Shetty¹,

Bose²

2013

J Regen Med Tissue Eng

View full text Add to dashboard Cite

Section: Discussionsupporting

confidence: 86%

Section: Discussionsupporting

confidence: 80%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

A clinical and radiographic evaluation of the management of periodontal osseous defects with alloplast and platelet rich plasma

Shetty¹,

Bose²

2013

J Regen Med Tissue Eng

View full text Add to dashboard Cite

“…Recently, several studies have demonstrated that TCP with platelet-derived growth factor is effective for high regeneration of bone. These results imply the significance of cells, signals and scaffolds in bone regeneration 6,14) .…”

Section: Treatments For the Filling Materials Tissue Response And Bmentioning

confidence: 60%

Effect of New Bone Substitute Materials Consisting of Collagen and Tricalcium Phosphate

Takahashi

2009

Bull. Tokyo Dent. Coll.

View full text Add to dashboard Cite

The purpose of this study was to investigate the effect of new bone substitute materials consisting of collagen and tricalcium phosphate (TCP). Prior to the experiment, mandibular dog teeth were extracted. After 3 months, specific cavities were prepared on the alveolar ridge. In one group, cavities were filled with collagen sponge (CS group), in the other, cavities were filled with TCP sponge (TCP group). Cavities with no fillings (Cont group) were created as controls. Mandibular bone was evaluated histopathologically at experimental time periods of 1, 2, 4, and 8 weeks. Due to the non critical inflammatory symptoms that each group showed throughout all the time periods investigated, a low irritation level was observed. Absorption of material was almost complete at after 4 weeks in the CS group, and at after 8 weeks in the TCP group. At the top of the cavity, the TCP group exceeded the Cont group in amount of neogenesis at after 8 weeks. The materials examined in this study showed good osteoconduction and biodegradable character. The TCP Group, in particular, showed highly acceptable results, demonstrating that the materials used were excellent candidates as bone substitute materials.

show abstract

“…Le β-TCP a de multiples utilisations en chirurgie orale (comblement sinusien, réparation de défauts osseux en implantologie et en parodontologie, etc. [20][21][22]). …”

Section: Matériaux De Comblement Osseux D'origine Synthétiqueunclassified

Intérêt de l’oxygénothérapie hyperbare dans l’optimisation de la cicatrisation osseuse en odontostomatologie

Gunepin

Derache

Pêcheur

et al. 2013

Med Buccale Chir Buccale

View full text Add to dashboard Cite

Résumé -En odontostomatologie, face à une perte de substance osseuse dont le comblement ne peut intervenir spontanément du fait des seules capacités physiologiques du patient (défaut osseux de taille critique), le praticien peut avoir recours à de nombreux matériaux de comblement osseux. Actuellement, le matériau de référence reste l'os du patient (greffe autogène). Cependant, pour des raisons liées parfois au manque de disponibilité de cet os et/ou à la morbidité potentielle accompagnant la création d'un second site opératoire, le praticien peut avoir recours à de l'os allogène (provenant d'un autre patient), de l'os xénogène (d'origine animal) ou à des matériaux de substitution osseuse d'origine naturelle ou synthétique. La correction de ces défauts osseux pouvant être essentielle en odontostomatologie (prévention de la survenue de fracture, possibilité d'entreprendre ultérieurement des traitements implantaires et prothétiques et préservation de l'esthétique), de nombreux auteurs ont étudié différentes techniques visant à optimiser le processus de cicatrisation osseuse. Dès les années 1960, l'oxygénothérapie hyperbare ou OHB a été proposée comme traitement adjuvant de la cicatrisation osseuse. L'OHB consiste en l'administration d'oxygène pur à un patient à une pression supérieure à celle du niveau de la mer. Actuellement il n'existe aucune preuve de l'efficacité ou de l'inefficacité de l'OHB sur la cicatrisation osseuse. Ceci s'explique par le manque de connaissance des mécanismes exacts de l'action de l'OHB sur le tissu osseux et sur l'absence de larges essais cliniques contrôlés randomisés. L'analyse de la littérature met cependant en exergue le fait que si l'OHB ne doit pas être utilisée systématiquement, son recours peut être envisagé en fonction de la lésion, du patient, du type de greffe réalisé et/ou du type de substitut osseux utilisé.Abstract -Interest of hyperbaric oxygen therapy in the optimization of bone healing in odontostomatology.

show abstract

Effect of Platelet‐Rich Plasma on the Healing of Intrabony Defects Treated With Beta Tricalcium Phosphate and Expanded Polytetrafluoroethylene Membranes

Abstract: At 1 year after surgery, both therapies resulted in significant PD reductions and CAL gains.

Cited by 80 publications

References 49 publications

A clinical and radiographic evaluation of the management of periodontal osseous defects with alloplast and platelet rich plasma

A clinical and radiographic evaluation of the management of periodontal osseous defects with alloplast and platelet rich plasma

Effect of New Bone Substitute Materials Consisting of Collagen and Tricalcium Phosphate

Intérêt de l’oxygénothérapie hyperbare dans l’optimisation de la cicatrisation osseuse en odontostomatologie

Contact Info

Product

Resources

About