Effect of polysaccharide fractions from Fortunella margarita on the fecal microbiota of mice and SCFA production in vitro

Gougunao tea polysaccharides ameliorate high-fat diet-induced hyperlipidemia and modulate gut microbiota

“…[14][15][16][17] Non-starch polysaccharides can be indirectly fermented by intestinal microorganisms once entering the intestinal environment and can modulate the metabolism function of gut microbiota, which is related to the levels of microbial metabolites. 18 Gougunao tea is made from young leaves of a famous green tea in Jiangxi Province of China, which is rich in various nutrients and chemical substances, such as trace elements (selenium, zinc, calcium, magnesium, etc. ), polysaccharides, amino acids, vitamins, and tea polyphenols.…”

Fu brick tea alleviates alcoholic liver injury by modulating the gut microbiota–liver axis and inhibiting the hepatic TLR4/NF-κB signaling pathway

“…SCFAs were the main metabolites of gut microbes and the primary energy source of colon cells, which could also act as signal molecules to regulate host metabolism apart from providing energy for the body. 38,46–48 The concentrations of acetic acid, propanoic acid, butyric acid, isobutyric acid, valeric acid, isovaleric acid and total acids in the cecal contents of mice are shown in Table 1. Compared with NC mice, the cecal concentrations of acetic acid, propanoic acid, butyric acid and isovaleric acid and total acids in alcohol-fed mice were significantly decreased (Fig.…”

“…SCFAs were the main metabolites of gut microbes and the primary energy source of colon cells, which could also act as signal mole-cules to regulate host metabolism apart from providing energy for the body. 38,[46][47][48] The concentrations of acetic acid, propanoic acid, butyric acid, isobutyric acid, valeric acid, isovaleric acid and total acids in the cecal contents of mice are shown in Table 1.…”

Protective effect of homogeneous polysaccharides of Wuguchong (HPW) on intestinal mucositis induced by 5-fluorouracil in mice

“…After HPW administration, the levels of total SCFAs, acetic acid and butyric acid increased, indicating that microbial activity gradually recovered. Some studies have shown that Bacteroides can participate in the metabolism of polysaccharides to form succinic acid, which can be used as a single carbon source to produce acetic acid and other SCFAs [ 55 ]. In our previous study, it was found that supplementation with polysaccharides from Wuguchong could modify the obesity status of mice fed a high-fat and high-sugar diet by increasing the abundance of Bacteroidetes and decreasing that of Firmicutes [ 13 ].…”