Effect of Prenatal Ultrasound Screening on Perinatal Outcome

Ewigman, Bernard; Crane, James P.; Frigoletto, Fredric D.; Lefevre, Michael; Bain, Raymond P.; McNellis, Donald

doi:10.1056/nejm199309163291201

Cited by 582 publications

(187 citation statements)

References 21 publications

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“…In the early nineties, the largest available series suggested an intrauterine detection rate of about 80% with alphafetoprotein screening and about 40% without [16,17,18,19]. Conversely, the recent data of our registry suggest a prominent role of ultrasound in the prenatal diagnosis of open spina bifida.…”

Section: Discussionmentioning

confidence: 80%

Prenatal Diagnosis of Open Spina Bifida in Emilia-Romagna

Ghi

Cocchi²,

Conti³

et al. 2015

Fetal Diagn Ther

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Objective: To report recent data on the epidemiology of pregnancies affected by open spina bifida in the Emilia-Romagna region of Italy. Methods: All cases of open spina bifida diagnosed in the Emilia-Romagna region between 2001 and 2011 and reported to the IMER regional registry were included in the study group. The pregnancy outcome was retrospectively assessed. Results: In the study period out of 390,978 babies born in Emilia-Romagna 126 cases of open spina bifida were reported to the IMER registry, resulting in a global prevalence of 3.2 per 10,000 births. Prenatal diagnosis was achieved in the vast majority of these cases (105/126; 83.3%) and in a great proportion of those women (85/105; 80.9%) who opted for termination of pregnancy. Conclusions: In a wide region of northern Italy where ultrasound anomaly scan is routinely offered to the general population, the vast majority of cases of open spina bifida are diagnosed antenatally and terminated electively.

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Section: Discussionmentioning

confidence: 80%

Prenatal Diagnosis of Open Spina Bifida in Emilia-Romagna

Ghi

Cocchi²,

Conti³

et al. 2015

Fetal Diagn Ther

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“…In most industrialized countries, screening programs for various anomalies have therefore been established over the past two decades, but the quality of screening depends on several factors, most important being the examiners' experience and competence [12,21]. Besides low-versus high-risk patient selection, the severity and location of a malformation is also critical.…”

Section: Introductionmentioning

confidence: 99%

Prenatal indices for mandibular retrognathia/micrognathia

et al. 2015

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“…Esta tasa es menor a las reportadas en otros estudios (4)(5)(6)(7)(8). Si se evalúa por anomalía específica, hubo baja detección de anomalías con gran compromiso de la anatomía, como lo son espina bífida, defectos de la pared abdominal, cardiopatía congénita, hernia diafragmática y, labio y paladar hendidos, entre otros.…”

Section: Discussionunclassified