Effect of Probiotics Bacillus coagulans and Lactobacillus plantarum on Lipid Profile and Feces Bacteria of Rats Fed Cholesterol-Enriched Diet

Aminlari, Ladan; Shekarforoush, Seyed Shahram; Hosseinzadeh, Saeid; Nazifi, Saeed; Sajedianfard, Javad; Eskandari, Mohammad Hadi

doi:10.1007/s12602-018-9480-1

Cited by 42 publications

(19 citation statements)

References 22 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…However, these previous investigations did not mention the further utilization of the biomass and the byproducts derived from the small sugars, e.g., carbon dioxide, ethanol and/or glycerol. Probiotic bacteria offer a better alternative that explores their proven health benefits and safety as food additives [39]. We are unaware of any previous studies in which probiotic microbes have been used for the treatment of FOS, possibly because many probiotic bacteria (including lactobacilli and bifidobacteria) hydrolyze and utilize short-chain oligosaccharides [56,57].…”

Section: Discussionmentioning

confidence: 99%

“…In this study, we selected probiotic Bacillus coagulans (formerly Lactobacillus sporogenes [36]), a facultative anaerobic spore-forming bacterium that converts monosaccharides and disaccharides into lactic acid under anaerobic conditions. According to the definition by Food and Agricultural Organization of the United Nations, and World Health Organization, probiotics refer to live microorganisms that, when in adequate numbers, confer a health benefit on the host [37,38], such as preventing the growth of pathogens, reducing serum lipid levels, and modulating the immune response [6,12,39,40]. B. coagulans is a competitive probiotic species because its spore-forming ability allows it to remain viable in the gastrointestinal tract despite the pH extremes and the presence of digestive enzymes.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Removal of Small-Molecular Byproducts from Crude Fructo-Oligosaccharide Preparations by Fermentation Using the Endospore-Forming Probiotic Bacillus coagulans

et al. 2020

View full text Add to dashboard Cite

Short-chain prebiotic fructo-oligosaccharides (FOS) produced by enzymatic conversion from sucrose often contains high concentration of monosaccharides as byproducts. In addition to conventional physical/chemical purification processes, microbial treatment is an alternative method to remove these byproducts. We used Bacillus coagulans to reduce the abundance of byproducts during the enzymatic production of FOS. It is a promising probiotic because this thermophilic and spore-forming bacterium remains viable and stable during food processing and storage. B. coagulans also produces lactic acid during the carbohydrate metabolism and is used industrially to produce lactic acid for medical and food/feed applications. We aimed to establish an evaluation system to screen different strains of B. coagulans for their performance and selected B. coagulans Thorne for the treatment of crude FOS due to its high growth rate, high sporulation rate, and low nutrient requirements. B. coagulans preferentially utilized monosaccharides over other sugar components of the FOS mixture. Glucose and fructose were completely consumed during the fermentation but 85% (w/w) of the total FOS remained. At the end of the fermentation, the total viable cell count of B. coagulans Thorne was 9.9 × 108 cfu·mL−1 and the maximum endospore count was 2.42 × 104 cfu·mL−1.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Removal of Small-Molecular Byproducts from Crude Fructo-Oligosaccharide Preparations by Fermentation Using the Endospore-Forming Probiotic Bacillus coagulans

et al. 2020

View full text Add to dashboard Cite

show abstract

“…The concomitant decrease in the levels of liver lipid (Figure 2A) and visceral fat (Table 3) followed a parallel trend. Many researchers have also discussed that the inclusion of probiotics (B. coagulans, L. plantarum, L. paracasei, and others) in high-fat or high-cholesterol diets could effectively decrease lipid accumulation in liver (Aminlari et al, 2018;Chiu et al, 2006;El-Shafie et al, 2009;Kim et al, 2017).…”

Section: A-dmentioning

confidence: 99%

“…The increasing level of SCFAs might elevate release of the hormone glucagon-like peptide-1 (GLP-1), subsequently resulting in decreased food consumption and body weight gain (Yadav et al, 2013). Long-term ingestion of Bacillus coagulans and Lactobacillus paracasei could regulate gut microbes and modulate triglyceride deposition into adipocytes (Aminlari et al, 2018). Bacillus coagulans was also found capable of exerting an antagonistic effect on intestinal coliform contributing to the displacement of a considerable population of coliforms in gut (Haldar & Gandhi, 2016).…”

Section: Introductionmentioning

confidence: 99%

Bacillus coagulans BC198 and Lactobacillus paracasei S38 in combination reduce body fat accumulation and modulate gut microbiota

Hsieh

You

Dai

et al. 2020

CyTA - Journal of Food

View full text Add to dashboard Cite

Bacillus coagulans BC198 and Lactobacillus paracasei S38 in combination reduce body fat accumulation and modulate gut microbiota. This study investigated the effects of two single strains (Bacillus coagulans BC198 and Lactobacillus paracasei S38) at a level of 5 × 10 9 CFU and a mixture of these two strains (1 x 10 8 CFU) on body fat accumulation and gut microbiota in rats. In contrast to high-fat control, L. paracasei S38 intakes resulted in significant (p < .05) reductions in total visceral fat (−15%) and liver lipids (−19%). The supplementation of the multi-strain mixture at a relatively lower dose was more efficient (p < .05) in reducing feed efficiency (−17%), total visceral fat (−30%), and liver lipids (−32%). A higher concentration of total short-chain fatty acids and a higher proportion of Bacteroidetes were also observed in the fecal samples of the multi-strain group. Consumption of multiple strains of B. coagulans BC198 and L. paracasei S38 appeared to show greater efficacy than single strains even at a relatively low dose. El Bacillus coagulans BC198 y el Lactobacillus paracasei S38 combinados reducen la acumulación de grasa corporal y modulan la microbiota intestinal RESUMEN El presente estudio se propuso investigar los efectos de dos cepas individuales (Bacillus coagulans BC198 y Lactobacillus paracasei S38) a un nivel de 5 × 10 9 UFC y de una mezcla de estas dos cepas (1 x 10 8 UFC) en la acumulación de grasa corporal y la microbiota intestinal de las ratas. En contraste con el control de grasas, la ingesta de L. paracasei S38 provocó reducciones significativas (p < .05) de la grasa visceral total (−15%) y los lípidos hepáticos (−19%). La suplementación con la mezcla de múltiples cepas a una dosis relativamente más baja fue más efectiva (p < .05) para reducir la eficiencia de la alimentación (−17%), la grasa visceral total (−30%) y los lípidos hepáticos (−32%). Asimismo, se observó mayor concentración de ácidos grasos totales de cadena corta (SCFA) y mayor proporción de Bacteroidetes en las muestras fecales del grupo que consumió cepas múltiples. En conclusión, el consumo de cepas múltiples de B. coagulans BC198 y L. paracasei S38 parece tener mayor eficacia que las cepas individuales, incluso a una dosis relativamente baja, para reducir la acumulación de grasa corporal y modular la microbiota intestinal.

show abstract

“…Bacillus coagulans has been found to be an effective biotherapeutic agent in human and animal health promotion programmes (Bader et al ; Aminlari et al ; Haldar and Gandhi ). However, inadequate information is available for vacuum‐dried milk powder with Bacillus probiotics .…”

Section: Introductionmentioning

confidence: 99%

Development of vacuum‐dried probiotic milk powder with Bacillus coagulans

Haldar

Gandhi

2019

Int J of Dairy Tech

View full text Add to dashboard Cite

The present study explored the possibilities of using Bacillus coagulans as a probiotic culture in vacuum-dried milk powder. The operational drying temperature at 63 AE 2°C under 0.7 kg/cm 2 pressure emerged as the best temperature at which to prepare dried milk powder within 4.5 h with a mean (AESEM) Bacillus coagulans B37 spore count of 8.78 AE 0.03 log cfu/g and moisture content of 4.82 AE 0.12%. The total spore counts in vacuum-dried milk powder did not change (P > 0.10) at storage temperatures of 7°C, 37°C or 45°C over a three-month period.

show abstract

Effect of Probiotics Bacillus coagulans and Lactobacillus plantarum on Lipid Profile and Feces Bacteria of Rats Fed Cholesterol-Enriched Diet

Cited by 42 publications

References 22 publications

Removal of Small-Molecular Byproducts from Crude Fructo-Oligosaccharide Preparations by Fermentation Using the Endospore-Forming Probiotic Bacillus coagulans

Removal of Small-Molecular Byproducts from Crude Fructo-Oligosaccharide Preparations by Fermentation Using the Endospore-Forming Probiotic Bacillus coagulans

Bacillus coagulans BC198 and Lactobacillus paracasei S38 in combination reduce body fat accumulation and modulate gut microbiota

Development of vacuum‐dried probiotic milk powder with Bacillus coagulans

Contact Info

Product

Resources

About