Effect of Prostaglandin F2α on Luteal Function in Swine2

Diehl, John R.; Day, Billy N.

doi:10.2527/jas1974.392392x

Cited by 109 publications

(41 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The CL of the cycling female pig is resistant to prostaglandin F 2α (PGF 2α )-induced luteolysis prior to day 12 of the estrous cycle [2,4,11]. By contrast, the CL of pseudopregnant females induced by the above methods regresses rapidly after PGF 2α administration [5,17], and 83 − 92% of gilts [13,17,27] and 100% of sows [18] exhibit estrus 5 days after PGF 2α treatment, as well as pregnant females [5,21].…”

mentioning

confidence: 99%

Reproductive Hormone Profiles in Sows on Estrus Synchronization using Estradiol Dipropionate and Prostaglandin F<sub>2α</sub>-Analogue and the Reproductive Performance in Female Pigs on Commercial Farms

Noguchi

Kashiwai

Itoh

et al. 2013

The Journal of Veterinary Medical Science

View full text Add to dashboard Cite

ABSTRACT. Changes in ovarian structures and hormonal profiles in estradiol dipropionate (EDP)-induced pseudopregnant sows following PGF 2α -analogue (PGF 2α -A) administration and practicality of the estrus synchronization protocol using EDP and PGF 2α -A on estrus expression and reproductive performance in commercial conditions were investigated. Pseudopregnancy was defined as absence of estrus maintained for at least 20 days after EDP treatment in this study. When 4 pseudopregnant sows induced by 20 mg EDP were treated with PGF 2α -A as 0.175 mg cloprostenol twice at a 24-hr interval between 20 and 28 days after EDP treatment, plasma progesterone concentrations rapidly decreased after treatment. The luteinizing hormone surge and ovulation were detected in all sows. The number of ovulated follicles was 17.3 ± 1.1 (SEM). On commercial farms, 94.2% of 52 gilts and 95.2% of 21 sows received EDP became pseudopregnant. When these pseudopregnant females (48 gilts and 20 sows) were treated with PGF 2α -A as described above, estrus was detected in all females at 6.1 ± 0.3 days for gilts and 5.5 ± 0.2 days for sows after the first PGF 2α -A treatment. There were no significant differences in farrowing rate (85.0 − 100%), average total litter size (10.0 − 11.4), average born alive litter size (9.4 − 10.3) and average piglet birth weight (1.56 − 1.71 kg) between PGF 2α -A treated pseudopregnant female pigs that were inseminated during synchronized estrus and females inseminated during spontaneous estrus. This study indicates that estrus synchronization programs using EDP and PGF 2α -A are available as practical and convenient procedures for commercial pig farms.

show abstract

mentioning

confidence: 99%

Reproductive Hormone Profiles in Sows on Estrus Synchronization using Estradiol Dipropionate and Prostaglandin F<sub>2α</sub>-Analogue and the Reproductive Performance in Female Pigs on Commercial Farms

Noguchi

Kashiwai

Itoh

et al. 2013

The Journal of Veterinary Medical Science

View full text Add to dashboard Cite

show abstract

“…Blood was collected daily at 1000 h from day 0 to 9 and on day l0; at I 100 h and I200 h on days 9 and 10, and otherwise at 6-h intervals from noon on day 9 until day l3 (96 h Henricks et al (1972) to occur during the estrous cycle of the pig. (Louis et al 1975 (Diehl and Day 1974;Killian et al 1975).…”

mentioning

confidence: 99%

EFFECTS OF PROSTAGLANDIN F_2α ON THE ESTROUS CYCLE AND HORMONE LEVELS IN THE GILT

Connor¹,

Phillips²,

Palmer³

1976

Can. J. Anim. Sci.

View full text Add to dashboard Cite

din F2o on the estrous cycle and hormone levels in the gilt. Can. J. Anim. Sci. 56: 661_669.Two experiments were conducted using cycling crossbred gilts 7-9 mo of age.Blood samples were taken daily at I000 h from day 0 (first day of estrus) to the day of PGF2' injection; at I h and 2 h post treatment, and subsequently every 6 h for 96 h; then daily until the next estrus. In experiment I,20 mg PGF2' was injected intramuscularly (i m ) to three gilts on day 9 (tr) and to three gilts on day 9 and again on da1' l0 (t2). In experiment II, three gilts were injccted i.m. with 20 mg PGF2* on day 12. In both experiments, control blood samplcs were collected from three of the gilts for one estrous cycle prior to the treatment cycle. Serum progesterone (P) dropped significantly (P<.01) in t1 from a pre-injection mean (+SE) of 8.9 ,t 0.7 ng/ml to 4.8 + 0.U ng/ml 8 h afier injection. In 12, P decreascd significantly (P<.05) on day 9 from a mean prior to injection of I 1 .2 + 2.3 ng/ml to 7.5 t 1 .8 ng/ml by 8 h post injection. Similarly, following PGF2' on day 10, P levels dropped sharply (P<.05) fiom a mean of 8.3 + 0.8 ng/ml prior to injection to 3.8 + 0.4 ng/ml 8 h later. These decrcascs $ere not seen in controls. In all cases. ercept onc, P recovered to normal levels by 96 h and followed a pattern similar to the controls. In experiment II, scrum P declined (P<.0-5) frtrm a pre-in.iection mean of 12.8 + 0.9 ng/ml to 1.9 + A.1 ng/ml by 2 h after treatment and continued to fall. In contrast, P concentrations on day l2 of thc control cycle rerrained relatively constant. Mean estrogen (E) lcvcls increased slightly within thc first hour post injcction in both experiments, but were significantly elevated (P <.01) above the pre-injection mean only in t, gilts on day 9. Subsequently. E patterns were similar to those of thc control cycles. No consistent changes were observed in mean LH concentrations following treatment. Cycle length was unaffected by PGF2. treatment on da1' 9, or on days 9 and 10. When PGF2' was in.jccted on day 12, estrus occurred an averagc of 1.7 days earlier than in the control cycle (P<.05

show abstract

“…These authors were among the earliest researchers who reported that no luteolytic effect was observed when PGF 2α was administered to cycling gilts on day 10 and 12 of the estrous cycle. These same authors also observed that PGF 2α did show abortifacient effects when administered to pregnant gilts at 25 to 30 days post conception (6).…”

Section: Introductionmentioning

confidence: 67%

“…Contrastingly, in female swine a single treatment with PGF 2α is not effective for inducing luteolysis until after Day 12 of the estrous cycle (6,7), and therefore cannot be utilized for estrus synchronization. The reason for the species difference in luteolytic activity of exogenous PGF 2α is still unclear (8).…”

Section: Introductionmentioning

confidence: 98%

See 1 more Smart Citation

Estrus Responses and Hormonal Profiles of Gilts Following Treatments with Prostaglandin F_2α

Alimi

Leigh

Ajala

et al. 2017

Macedonian Veterinary Review

View full text Add to dashboard Cite

This study investigated the effect of three intramuscular injections of Prostaglandin F 2α (PGF 2α ) administered seven days apart on estrus responses and some reproductive hormonal profiles in post-pubertal gilts.Sixteen gilts were divided into groups A, B, C, and D, with four animals in each group. Group A, B and C gilts were treated with PGF 2α injections intramuscularly at doses 5mg,7.5mg and 10mg per gilt respectively on Days 0, 6 and 13 of the experiment. Group D (Control) were treated with intramuscular injections of 2ml phosphate-buffered saline (PBS) instead. Serum samples were collected every 24 hours for four days after each PGF 2α injection and estrus detection was conducted daily. Results showed that 100% of Group A came into estrus 96 hours after the second PGF 2α injection,while 50% of Group B came into estrus after the first injection; with the other 50% exhibiting estrus following the 2nd injection. Only 50% of Group C displayed estrus signs and this was observed following the second PGF 2α injection. Control gilts did not express behavioral estrus during this study, suggesting that PGF 2α may have induced estrus in the treated animals. LH and estradiol concentrations were significantly different in Group A and B when compared to the control following the 2nd PGF 2α injection. In all, it was observed that serum concentrations of LH, FSH and oestradiol-17β reached maximal levels just prior to expression of estrus, thus suggesting that the pattern of reproductive hormonal changes in PGF 2α -synchronized gilts may be quite similar to those of naturally cycling in-estrus gilts.

show abstract

Effect of Prostaglandin F2α on Luteal Function in Swine2

Cited by 109 publications

References 0 publications

Reproductive Hormone Profiles in Sows on Estrus Synchronization using Estradiol Dipropionate and Prostaglandin F<sub>2α</sub>-Analogue and the Reproductive Performance in Female Pigs on Commercial Farms

Reproductive Hormone Profiles in Sows on Estrus Synchronization using Estradiol Dipropionate and Prostaglandin F<sub>2α</sub>-Analogue and the Reproductive Performance in Female Pigs on Commercial Farms

EFFECTS OF PROSTAGLANDIN F_2α ON THE ESTROUS CYCLE AND HORMONE LEVELS IN THE GILT

Estrus Responses and Hormonal Profiles of Gilts Following Treatments with Prostaglandin F_2α

Contact Info

Product

Resources

About

Effect of Prostaglandin F2α on Luteal Function in Swine2

Cited by 109 publications

References 0 publications

Reproductive Hormone Profiles in Sows on Estrus Synchronization using Estradiol Dipropionate and Prostaglandin F<sub>2α</sub>-Analogue and the Reproductive Performance in Female Pigs on Commercial Farms

Reproductive Hormone Profiles in Sows on Estrus Synchronization using Estradiol Dipropionate and Prostaglandin F<sub>2α</sub>-Analogue and the Reproductive Performance in Female Pigs on Commercial Farms

EFFECTS OF PROSTAGLANDIN F2α ON THE ESTROUS CYCLE AND HORMONE LEVELS IN THE GILT

Estrus Responses and Hormonal Profiles of Gilts Following Treatments with Prostaglandin F2α

Contact Info

Product

Resources

About

EFFECTS OF PROSTAGLANDIN F_2α ON THE ESTROUS CYCLE AND HORMONE LEVELS IN THE GILT

Estrus Responses and Hormonal Profiles of Gilts Following Treatments with Prostaglandin F_2α