Effect of pterostilbene on lipids and lipid profiles in streptozotocin-nicotinamide induced type 2 diabetes mellitus

Satheesh, M. Amarnath; Pari, Leelavinothan

doi:10.32725/jab.2008.005

Cited by 60 publications

(41 citation statements)

References 23 publications

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“…Oral administration of diosgenin significantly lowered PLs in tissues of rats with HFD‐STZ‐induced diabetic rats. Several studies have reported that the increased PL levels in tissues of experimental diabetic rats . An enhanced peroxide radical in diabetes causes membrane damage, which may be responsible for the increased phospholipids .…”

Section: Discussionmentioning

confidence: 95%

Diosgenin reorganises hyperglycaemia and distorted tissue lipid profile in high-fat diet-streptozotocin-induced diabetic rats

Naidu

Ponmurugan²,

Begum³

et al. 2015

J. Sci. Food Agric.

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Section: Discussionmentioning

confidence: 95%

Diosgenin reorganises hyperglycaemia and distorted tissue lipid profile in high-fat diet-streptozotocin-induced diabetic rats

Naidu

Ponmurugan²,

Begum³

et al. 2015

J. Sci. Food Agric.

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“…We previously demonstrated pterostilbene as a PPARα agonist, and decreased plasma glucose, very‐low‐density lipoprotein (VLDL)‐, low‐density lipoprotein (LDL)‐, and total cholesterol, and increases HDL‐cholesterol levels in hamsters fed a high‐fat diet, effects that are consistent with PPARα activation . Other groups have also reported anti‐diabetic and hypolipidemic properties of pterostilbene . Resveratrol has been reported to bind to PPARα .…”

Section: Introductionmentioning

confidence: 90%

Evaluation of PPARα activation by known blueberry constituents

et al. 2015

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Anthocyanins and catechins do not appear to contribute to the up-regulation of hepatic PPARα expression observed in hamsters. While pterostilbene and resveratrol demonstrated PPARα activation, their levels in BBX do not seem to be at efficacious concentrations. These stilbenes may contribute to the up-regulation of PPARα expression by acting synergistically with each other or with other constituents in BBX.

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“…The mean values were calculated. Rats were rendered diabetic if FBS level was greater than 250 mg/dl [10].…”

Section: Biochemical Studiesmentioning

confidence: 99%

The effect of bone marrow-derived mesenchymal stem cells on the healing of experimental skin wound in diabetic adult male albino rats

Mohammed

Moussa

Shaker

et al. 2014

The Egyptian Journal of Histology

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which wounded diabetic rats were treated with bone marrow-derived mesenchymal stem cells. Diabetes was induced in rats by means of a single intraperitoneal injection of streptozotocin. Wounds of groups III and IV were examined after 3 and 7 days. Skin specimens were processed and stained with H&E and Masson's trichrome. ResultsRe-epithelization with complete closure of the wound was noted in the stem celltreated group after 7 days. There was a significant increase in the number of hair follicles/high-power field and increase in the collagen content of the dermis in the stem cell-treated groups compared with the untreated groups. ConclusionBone marrow-derived mesenchymal stem cells can be effectively used in the treatment of diabetic wounds.

show abstract

Effect of pterostilbene on lipids and lipid profiles in streptozotocin-nicotinamide induced type 2 diabetes mellitus

Cited by 60 publications

References 23 publications

Diosgenin reorganises hyperglycaemia and distorted tissue lipid profile in high-fat diet-streptozotocin-induced diabetic rats

Diosgenin reorganises hyperglycaemia and distorted tissue lipid profile in high-fat diet-streptozotocin-induced diabetic rats

Evaluation of PPARα activation by known blueberry constituents

The effect of bone marrow-derived mesenchymal stem cells on the healing of experimental skin wound in diabetic adult male albino rats

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