1953
DOI: 10.2337/diab.2.5.345
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Effect of Purified Glucagon (Hyperglycemic-Glycogenolytic Factor, HGF) on Carbohydrate and Corticoid Metabolism in Normal and Diabetic Subjects

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Cited by 37 publications
(9 citation statements)
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“…After glucagon stimulation (2 mg intravenously) blood glucose levels were followed at 10-minute intervals for 60 minutes. Results were compared to those of Kirtley, Waife, Helmer, and Peck (17).…”
Section: Methodsmentioning
confidence: 99%
“…After glucagon stimulation (2 mg intravenously) blood glucose levels were followed at 10-minute intervals for 60 minutes. Results were compared to those of Kirtley, Waife, Helmer, and Peck (17).…”
Section: Methodsmentioning
confidence: 99%
“…Responsiveness to glucagon increased during the course of insulin coma therapy. 5. Glucagon was usually successful in terminating insulin coma and it is suggested that glucagon has some advantages as a means of routine termination of insulin coma and that a further clinical trial is warranted.…”
Section: Discussionmentioning
confidence: 99%
“…There is general agreement that glucagon can cause at least a temporary rise in the blood sugar level in the presence of insulin. However, considerable interest still centers around the question of the relative effects of insulin and glucagon on the blood sugar level (2)(3)(4)(5).…”
mentioning
confidence: 99%
“…Glucose in whole blood was measured by the method of Somogyi (16,17), as modified by Nelson (18). Venous blood samples were obtained with a minimum of stasis from an antecubital vein, and almost simultaneously, capillary blood (which has the 5 Later studies have shown that prolonged injection of glucagon is not necessary. Comparable hyperglycemic responses can be induced when the same amount of glucagon diluted in 10 ml.…”
Section: Methodsmentioning
confidence: 99%
“…Sutherland and Cori (2) have shown that glucagon increases the concentration of active phosphorylase in liver slice preparations. Apparently, glucagon administration does not induce glycogenolysis in muscle (4,5).…”
mentioning
confidence: 86%