Effect of quercetin against lindane induced alterations in the serum and hepatic tissue lipids in wistar rats

Effects of Dietary Quercetin on Growth Performance, Serum Lipids Level and Body Composition of Tilapia (Oreochromis Niloticus)

“…They also found that TC levels in flounder fed diets contained quercetin were significantly lower after 60 days compared with 30 days. Moreover, similar results about quercetin in the reduction of serum or hepatic lipids were previously reported in rats (Basarkar and Nathn, 1983;Igarashi and Ohmura, 1995;Ricardo et al, 2001;de Boer et al, 2006;Krishnaveni et al, 2010;Hu et al, 2012;Padma et al, 2012), mice (Kobori et al, 2011;Zhang et al, 2012), chicken (Qureshi et al, 2011) , rabbits (Kamada et al, 2005) and humans (Arai et al, 2000;Egert et al, 2010) . Yugarani et al (1992) found that quercetin did not cause any significant changes on the plasma TC, TG and liver fat at weeks 4, 7 and 10 in the rats fed high fat diet, and Nakamura et al (2000) also indicated that oral quercetin (1.0g/kg) had no remarkable influence on lipid concentrations of serum and hepatic and fecal steroid excretion in rats.…”

“…In addition to the antioxidant properties of oral administration of quercetin, there is potential effect on lowering levels of lipid in mammal animals (Basarkar and Nathn 1983;Igarashi and Ohmura 1995;Ricardo et al, 2001;Kamada et al 2005;de Boer et al, 2006;Krishnaveni et al, 2010;Kobori et al, 2011;Hu et al, 2012;Padma et al, 2012;Zhang et al, 2012) and poultry (Qureshi et al, 2011). However, there also seemed no remarkable influence on serum and hepatic lipid concentrations of rats (Ruttus norvegicus) (Yugarani et al, 1992;Nakamura et al, 2000).…”

Hepatoprotective Effect of Quercetin Pretreatment Against Paracetamol-Induced Liver Damage and Partial Hepatectomy in Rats

“…Necrosis takes place in this location because zone 3 cells have the highest concentration of cytochrome P-450 and also because this is where the drug is converted into active metabolites 27,28,29,30,31,32 . Dahlin et al 33 , Moore et al 34 , and Padma et al 35 investigated the action of quercetin on the toxicity of lindane, a substance affecting the homeostasis of glutathione and causing alterations in P-450 cytochrome P450 monooxygenase enzymes. Those authors confirmed the efficacy of quercetin, attributed to a potent antioxidant activity.…”

Protective effect of (−)-epigallocatechin-3-gallate on capsaicin-induced DNA damage and oxidative stress in human erythrocyes and leucocytes in vitro

“…More than 4,000 varieties of flavonoids have been identified. The flavones are characterized by a planar structure because of a double bond in the central aromatic ring (Padma et al 2012). The flavanol epigallocatechin-3gallate (EGCG) is the most abundant catechin in green tea which is the unfermented extract of the leaves of Camellia sinensis.…”