Effect of Quinidine Sulphate in Inhibiting Ventricular Fibrillation

Acute, Fatal Coronary Insufficiency

“…After injection into cats, quinidine raises the threshhold for the induction of ventricular fibrillation by faradic stimulation. 18 In such experiments the heart is normal and the method of producing the arrhythmia artificial. In patients, Morawitz and Hochrein 10 believe that they have employed quinidine prophylactically with success in that the number of sudden cardiac deaths in the Leipzig clinic was diminished by giving 0.2 Gm.…”