Effect of radiotherapy after breast-conserving surgery in elderly patients with early breast cancer according to the AJCC 8th Edition Breast Cancer Staging System in Japan

Tang, Liuwei; Ma, Zichang; Ishikawa, Yojiro; Matsushita, Haruo; Ishida, Toru; Jingu, Keiichi

doi:10.1007/s12282-020-01181-1

Cited by 7 publications

(5 citation statements)

References 19 publications

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“…SBRT gathers the X-ray in the tumor location with accurate location and reasonable dose distribution in the target area, and the adjacent tissues only receive a safe dose. This treatment can effectively control the tumor growth and improve the patients' quality of life [ 17 , 18 ]. In this study, there were 4 patients and 12 patients having adverse reactions in the experimental group and control group, respectively, indicating that SBRT had higher safety compared with conventional treatment.…”

Section: Discussionmentioning

confidence: 99%

Effect of Stereotactic Body Radiation Therapy Combined with Thermoplastic Fixation on Set-Up Errors in Breast Cancer Patients Undergoing Radiotherapy

Zhu

Liu

et al. 2022

Computational and Mathematical Methods in Medicine

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Objective. To investigate the effect of stereotactic radiotherapy (SBRT) combined with thermoplastic fixation on set-up error in breast cancer (BC) patients undergoing radiotherapy. Methods. Ninety BC patients undergoing radiotherapy who were treated in our hospital (May 2019-May 2020) were selected as the research objects and equally divided into the experimental group and control group according to the order of hospitalization, with 45 patients in each group. The control group received conventional radiotherapy combined with breast bracket, and the experimental group received SBRT combined with thermoplastic fixation. The incidences of adverse reactions, 1-year survival rates, and set-up errors were compared between the two groups. Results. Compared with the control group, the experimental group had much lower total incidence of adverse reactions and remarkably higher 1-year survival rate. The translational errors ( X direction, Y direction, and Z direction), translational errors after rotation ( X direction, Y direction, and Z direction), and rotation errors ( X direction, Y direction, and Z direction) in the experimental group were obviously lower compared with those in the control group. Conclusion. Implementing SBRT combined with thermoplastic fixation in BC patients undergoing radiotherapy can effectively improve set-up efficiency and treatment accuracy and reduce set-up errors. Compared with the breast bracket, the combination of SBRT and thermoplastic fixation has higher application value, and further studies are conducive to providing patients with a better solution plan.

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Section: Discussionmentioning

confidence: 99%

Effect of Stereotactic Body Radiation Therapy Combined with Thermoplastic Fixation on Set-Up Errors in Breast Cancer Patients Undergoing Radiotherapy

Zhu

Liu

et al. 2022

Computational and Mathematical Methods in Medicine

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“…Ver-ification studies based on Asian or Chinese population has been carried out. [14][15][16][17] Based on a single center study, combined with the diagnosis and treatment, this paper discusses the verification of the new staging system based on the real-world data.…”

Section: Introductionmentioning

confidence: 99%

Validation of the Eighth American Joint Committee on Cancer Anatomic and Prognostic Staging System for Breast Cancer

Yang

Peng

Lian

et al. 2022

Journal of Surgical Research

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“…The incidence of severe adverse events was lower than expected from past patients based on our experience of 3.2%, who were treated with conventional fractionated 3D-CRT with free breathing [ 9–13 ]. The results of this trial suggested that VMAT under the condition of DIBH in hypofractionated radiotherapy for left-sided breast cancer after breast-conserving surgery can be performed safely in Japanese women.…”

Section: Discussionmentioning

confidence: 84%

VMAT with DIBH in hypofractionated radiotherapy for left-sided breast cancer after breast-conserving surgery: results of a non-inferiority clinical study

Jingu,

Ito,

Sato

et al. 2023

Journal of Radiation Research

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The purpose of this study was to show the safety of volumetric modulated arc therapy (VMAT) with deep inspiration breath-hold (DIBH) in hypofractionated radiotherapy for left-sided breast cancer after breast-conserving surgery in a clinical setting. Twenty-five Japanese women, aged 20–59 years, who were enrolled in this prospective non-inferiority study received VMAT under the condition of DIBH with 42.4 Gy/16 fractions for whole-breast irradiation (WBI) ± boost irradiation for the tumor bed to show the non-inferiority of VMAT with DIBH to conventional fractionated WBI with free breathing. The primary endpoint was the rate of occurrence of radiation dermatitis of Grade 3 or higher or pneumonitis of Grade 2 or higher within 6 months after the start of radiotherapy. This study was registered with UMIN00004321. All of the enrolled patients completed the planned radiotherapy without interruption. The evaluation of adverse events showed that three patients (12.0%) had Grade 2 radiation dermatitis. There was no other Grade 2 adverse event and there was no patient with an adverse event of Grade 3 or higher. Those results confirmed our hypothesis that the experimental treatment method is non-inferior compared with our historical results. There was no patient with locoregional recurrence or metastases. In conclusion, VMAT under the condition of DIBH in hypofractionated radiotherapy for left-sided breast cancer after breast-conserving surgery can be performed safely in a clinical setting.

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Effect of radiotherapy after breast-conserving surgery in elderly patients with early breast cancer according to the AJCC 8th Edition Breast Cancer Staging System in Japan

Cited by 7 publications

References 19 publications

Effect of Stereotactic Body Radiation Therapy Combined with Thermoplastic Fixation on Set-Up Errors in Breast Cancer Patients Undergoing Radiotherapy

Effect of Stereotactic Body Radiation Therapy Combined with Thermoplastic Fixation on Set-Up Errors in Breast Cancer Patients Undergoing Radiotherapy

Validation of the Eighth American Joint Committee on Cancer Anatomic and Prognostic Staging System for Breast Cancer

VMAT with DIBH in hypofractionated radiotherapy for left-sided breast cancer after breast-conserving surgery: results of a non-inferiority clinical study

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