Effect of renal function on serum concentration of 1,5‐anhydroglucitol in type 2 diabetic patients in chronic kidney disease stages I–III: A comparative study with HbA1c and glycated albumin

Abstract

In clinical practice, age and renal function must be taken into consideration when interpreting 1,5-AG levels, even in the absence of advanced renal impairment.

Serum 1,5-Anhydroglucitol Concentrations Remain Valid as a Glycemic Control Marker In Diabetes with Earlier Chronic Kidney Disease Stages

“…Christoph Hasslacher et al found that there was a negative correlation between 1,5-AG and renal function which could be due to an age-related change in the glucose threshold. Consequently they concluded that in clinical practice, age and renal function must be taken into consideration when interpreting 1,5-AG levels, even in the absence of advanced renal impairment [2].…”

“…Won Jun Kim [1] conducted a cross-sectional study in 2012 and found that 1,5-AG levels were influenced by advanced renal impairment but not mild or moderate renal dysfunction. Nevertheless, Christoph Hasslacher et al [2] hold the opinion that In clinical practice, renal function must be taken into consideration when interpreting 1,5-AG levels, even in patients with earlier chronic kidney disease (CKD) stages. What's more, the sample sizes of these study were small.…”

“…* P < 0.052 Tg, triglycerid; LDL, low density lipoprotein; VLDL, very low density lipoprotein; Hcy, homocysteine; LDH, lactate dehydrogenase; CK, lactate dehydrogenase; CKMB, lactate dehydrogenase MB.…”

Effects of dietary carbohydrate on 1,5‐anhydroglucitol in a population without diabetes: results from the OmniCarb trial

“…The interpretation of 1,5-AG variation among adults without diabetes is unclear. It is thought that some of the differences among individuals may be accounted for by differences in renal reabsorption of 1,5-AG [21]. It is also possible that 1,5-AG varies as a result of factors that affect food digestion (for example, microbiota) [12] or nutrient absorption [13].…”

The impact of bariatric surgery on estimated glomerular filtration rate in patients with type 2 diabetes: a retrospective cohort study

“…eGFR was calculated using the MDRD (Modification of Diet in Renal Disease) formula. eGFR ≥ 120 mlsml/min/1.73m 2 was considered to be consistent with hyperfiltration as in previous studies [23][24][25] .…”