Effect of Repetitive Transcranial Magnetic Stimulation on Cortico Motor-Excitability Motor Function of the affected Hand in Subjects with Stroke

Srikumari,; Vengamma, B; Parvathi, G.

doi:10.5958/0973-5674.2015.00025.8

Cited by 2 publications

(2 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Seven [ 10 , 26 , 29 , 30 , 33 , 35 , 41 ] and 13 [ 43 , 45 , 47 , 48 , 61 – 63 , 66 , 70 , 73 , 74 , 76 , 77 ] studies evaluated the effects of a single session and multiple sessions of HF-rTMS on the affected M1 in cortical excitability, respectively. Khedr et al showed that more patients presented MEP responses after receiving 10 sessions of real HF-rTMS than sham [ 43 ].…”

Section: Resultsmentioning

confidence: 99%

“…A total of 12 studies performed various correlation analyses between TMS measures and motor impairment [ 43 , 48 – 50 , 56 , 57 , 59 , 61 – 63 , 70 , 71 , 75 ]. Cross-sectional analyses indicated positive correlations between the cortical excitability of the affected M1 and the severity of motor impairment of the hemiplegic arm [ 61 , 63 ], while that of the unaffected M1 was negatively correlated with motor impairment of the hemiplegic arm [ 71 ]. Furthermore, motor improvement was significantly correlated with a reduction in the cortical excitability of the unaffected M1 [ 56 , 57 , 59 ].…”

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Effects of transcranial magnetic stimulation in modulating cortical excitability in patients with stroke: a systematic review and meta-analysis

Bai

Zhang

Fong

2022

J NeuroEngineering Rehabil

View full text Add to dashboard Cite

Background Transcranial magnetic stimulation (TMS) has attracted plenty of attention as it has been proved to be effective in facilitating motor recovery in patients with stroke. The aim of this study was to systematically review the effects of repetitive TMS (rTMS) and theta burst stimulation (TBS) protocols in modulating cortical excitability after stroke. Methods A literature search was carried out using PubMed, Medline, EMBASE, CINAHL, and PEDro, to identify studies that investigated the effects of four rTMS protocols—low and high frequency rTMS, intermittent and continuous TBS, on TMS measures of cortical excitability in stroke. A random-effects model was used for all meta-analyses. Results Sixty-one studies were included in the current review. Low frequency rTMS was effective in decreasing individuals’ resting motor threshold and increasing the motor-evoked potential of the non-stimulated M1 (affected M1), while opposite effects occurred in the stimulated M1 (unaffected M1). High frequency rTMS enhanced the cortical excitability of the affected M1 alone. Intermittent TBS also showed superior effects in rebalancing bilateral excitability through increasing and decreasing excitability within the affected and unaffected M1, respectively. Due to the limited number of studies found, the effects of continuous TBS remained inconclusive. Motor impairment was significantly correlated with various forms of TMS measures. Conclusions Except for continuous TBS, it is evident that these protocols are effective in modulating cortical excitability in stroke. Current evidence does support the effects of inhibitory stimulation in enhancing the cortical excitability of the affected M1.

show abstract