INTRODUCTIONOvarian tumours account for 3% of all cancers in females, being the second most common cancer of the female genital tract, next only to uterine cancer.1 They account for 30% of all cancers of the female genital tract.2 Ovarian tumours often go undetected and present at a later stage. This is due to their location, lack of early screening modalities and, lack of specific symptoms and signs suggestive of malignant nature. The advanced stage at presentation of ovarian cancers results in a low mean 5 year survival rate and a poor prognosis. 2 The ovarian tumours are highly heterogenous with a wide range of histologic patterns enumerated in the WHO classification. The gross appearances are useful to a certain extent in distinguishing the individual tumours, more so for the ABSTRACT Background: Ovarian tumours account for 3% of all cancers amongst women, being the second most common cancer of the female genital tract. The ovarian tumours are highly heterogenous with a wide range of histological patterns. Aim of current study was to study the histological patterns and the age incidence of the ovarian tumours in our institute.
Methods:The present study is a prospective study conducted in the department of pathology, Andhra Medical College, from August 2011 to July 2013. Results: We received a total of 267 specimens of ovarian tumours during this period, out of which, 263 were primary and 4 were secondary tumours. Benign tumours were 209 (78.3%), borderline were 10 (3.7%) and malignant were 48 (18%) in numbers. Overall surface epithelial tumours constituted the majority of tumours accounting for 214 (80.2%) cases, followed by germ cell tumours 38 (14.2%) and sexcord stromal tumours 11 (4.1%). The single most common tumour diagnosed was serous cystadenoma. The most common malignant tumour was serous cystadenocarcinoma. The age groups affected ranged from 11-70 years. The peak age incidences for different histological types were as follows: surface epithelial tumours: 21-50 years, germ cell tumours: 21-30 years, sexcord stromal tumours: 51-60years. Benign tumours were more common in 21-40 years of age, borderline in 31-50 years and malignant tumours in 41-50 years age group.
Conclusion:The results from our study were comparable with those reported in literature; however malignant serous and mucinous tumours showed a lower peak age incidence in our study. Krukenberg tumours also occurred in younger age group in our study.
Seven cases of cardiomyopathy are presented with detailed macroscopical and microscopical studies. There are some differences and also similarities between this group and those described by Davies from Uganda. Myocytolysis was present in all cases, and appeared earlier than endocarditis. The earliest endocardial lesion was smooth muscle hyperplasia. Feeding of monkeys with plantains for more than 8 months failed to produce any changes in the heart. After Bedford and Konstam (I946) described dilatation of the heart with subendocardial fibrosis and mural thrombosis (the latter being an inconstant feature) there were numerous reports relating to cardiac failure due to cardiomyopathies of unknown aetiology. Under differing nomenclature, various authors described obscure heart diseases from all over the world-Davies (1948) from Uganda, Gillanders (I95I) and Becker, Chatgidakis, and van Lingen (1953) from South Africa, Edington and Jackson (I963) from Nigeria, and Hill, Still, and McKinney (I967) from Jamaica, O'Brien (I954) from Sudan, Nagaratnam and Dissanayake (I959) from Ceylon, and Andrade and Guimaraes (I964) from Brazil. From India the necropsy reports on cardiomyopathy were reviewed by Reddy, Murthy, and Rao (I969). The World Health Organization has conducted three International Meetings to elucidate the problem of cardiomyopathies and published them in the Bulletin ofthe WorldHealth Organization in I965 and I968 and in the Chronicle of the World Health Organization in I967. At these meetings, mention was made of the common incidence of endomyocardial fibrosis in Kerala State in the lower West coast of South India, and that idiopathic cardiomegaly (a name suggested for all the other types of cardiomyopathies apart from endomyocardial fibrosis in the Kingston Conference of W.H.O. (I967)) was quite often seen in the Delhi area. The present report is a study of seven necropsy reports from the Deccan Plateau of South India. Material and methods In 20IO necropsies (excluding stillbirths) between August I960 and June i969, there were 220
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.