Effect of resistance exercise during hemodialysis on physical function and quality of life: randomized controlled trial

Segura‐Ortí, Eva; Kouidi, Evangelia; Lisón, Juan Francisco

doi:10.5414/cnp71527

Cited by 94 publications

(115 citation statements)

References 27 publications

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“…26 Accordingly, Johansen et al 27 reported that resistance training improved quadriceps muscle area in HD patients similar to other studies with HD patients that confirmed important results about resistance training and improved knee strength, lean body mass, and physical capacity. [28][29][30] In the present study, patients who underwent RETP also improved the role physical of SF-36 after intervention while the control group did not present any changes in quality of life. In fact, studies have reported positive outcomes of intervention studies with exercise in quality of life, e.g., HD patients that performed resistance exercise improved significantly their mental health, 30 and resistance combined with aerobic exercise showed improvement of mental and physical components.…”

Section: Discussionmentioning

confidence: 57%

Effects of resistance exercise training on acyl-ghrelin and obestatin levels in hemodialysis patients

et al. 2015

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Background: Patients undergoing hemodialysis (HD) present altered levels of appetite hormones such as acyl-ghrelin (orexigenic) and obestatin (anorexigenic), which may contribute to anorexia. Physical exercise may affect these hormones and improve appetite in these patients. Objectives: The objective of this study is to evaluate the effects of a resistance exercise program in appetite hormones, body composition, and nutritional status in HD patients. Design: Intervention study with the control group. Subjects: Fifty-two patients on regular HD program were enrolled into two groups: 37 patients performed exercises (56.7% male, 45 ± 12.8 years, 57 (9-192) months on HD) and 15 patients comprised the control group (66.7% men, 50 ± 10.6 years, 57 (11-153) months on HD). Measurements: Exercise program (performed with elastic bands and ankle cuffs in both lower limbs) was supervised three times a week during 6 months (72 sessions). Patients had their blood drawn in a regular HD day after overnight fasting, before and after 6 months of exercise program. Obestatin, acyl-ghrelin, routine biochemical parameters, quality of life, and anthropometric data were collected and analyzed before and after 6 months. Results: After 6 months of exercise, obestatin levels reduced [from 3.0 ng/mL (2.3-3.4) to 1.9 ng/mL (0.6-3.4)] and acyl-ghrelin levels increased [from 21.5 pg/mL (1.3-77.7) to 37.2 pg/mL (16.7-94.1)] and the control group presented no significant differences in both plasma levels of hormones. Body composition and physical functional assessed by SF-36 and albumin levels (3.7 ± 0.3 to 3.9 ± 0.2, p50.05) improved after exercises. Conclusion: Six months of resistance exercises contributed to changes in plasma appetite hormones, body composition, and nutritional status in hemodialysis patients.

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Section: Discussionmentioning

confidence: 57%

Effects of resistance exercise training on acyl-ghrelin and obestatin levels in hemodialysis patients

et al. 2015

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“…Besides, most of the included trials conducted aerobic exercise (13 trials), 7 trials conducted resistance exercise, and only 4 trials conducted combined training. Segura-Orti et al [51] conducted a randomized controlled trial comparing resistance exercise and low intensity aerobic exercise, and found no differences in change-over-time between the two groups in any of the physical performance tests. While, in another study conducted by Afshar et al [7], there was greater reduction of serum creatine and hs-CRP (p < 0.001, each) in the aerobic group than in the resistance group.…”

Section: Discussionmentioning

confidence: 99%

Intradialytic Exercise in Hemodialysis Patients: A Systematic Review and Meta-Analysis

et al. 2014

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Background and Objective: Hemodialysis (HD) patients are more inactive, leading to poor functional capacity and quality of life; this may be reversed with intradialytic exercise training. To systematically evaluate the efficacy and safety of intradialytic exercise for HD patients, we conducted a meta-analysis of the published randomized controlled trials. Data Sources and Methods: Medline, Embase, and Cochrane Central Register of Controlled Trials were systematically searched up to February, 2014. The reference lists of eligible studies and relevant reviews were also checked. Results: 24 studies of 997 patients were included. Compared with control, intradialytic exercise significantly improve Kt/V (SMD = 0.27, 95% CI 0.01-0.53), peak oxygen consumption (VO_2peak) (SMD = 0.53, 95% CI 0.30-0.76), and physical performance of physical function of life (SMD = 0.30, 95% CI 0.04-0.55). However, no significant improvements were found in the mental function of life. There was no significant difference with respect to musculoskeletal and cardiovascular complications between the intradialytic exercise groups and control groups. Further subgroup analysis found that, when the trial duration was more than 6 months, the intervention had significant effects on VO_2peak (SMD = 0.89, 95% CI 0.56-1.22). However, when the trial duration was less than 6 months, the change of VO_2peak was not significant (SMD = 0.19, 95% CI -0.13 to 0.51). Conclusion: Intradialytic exercise can improve Kt/V, VO_2peak, and the physical quality of life, and intradialytic exercise is safe for HD patients. Therefore, we put forward the suggestion that clinical guideline be updated to inform clinicians on the benefits of intradialytic exercise on HD patients. i 2014 S. Karger AG, Basel

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“…A change in walking distance between 53 and 71 meters has been suggested as clinically meaningful in cardiopulmonary populations (41). Although not widely used as an outcome measure in exercise training studies in patients with CKD, improvements in the 6MW test of .53 meters have been reported (44)(45)(46)(47)(48)(49). We have found high variability on the 6MW test in dialysis patients (i.e., 3466127 meters at baseline) (48), possibly because (1) patients are unaware of how to pace themselves, (2) there is a wide spectrum of functioning in patients with CKD, and (3) although testing was done immediately before a midweek dialysis session, physiologic status (i.e., fluid, electrolytes, symptoms) vary significantly.…”

Section: Measurement Of Mobility and Physical Performance (Field Based)mentioning

confidence: 99%

Assessing Physical Function and Physical Activity in Patients with CKD

Painter

Marcus

2013

Clinical Journal of the American Society of Nephrology

168

118

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SummaryPatients with CKD are characterized by low levels of physical functioning, which, along with low physical activity, predict poor outcomes in those treated with dialysis. The hallmark of clinical care in geriatric practice and geriatric research is the orientation to and assessment of physical function and functional limitations. Although there is increasing interest in physical function and physical activity in patients with CKD, the nephrology field has not focused on this aspect of care. This paper provides an in-depth review of the measurement of physical function and physical activity. It focuses on physiologic impairments and physical performance limitations (impaired mobility and functional limitations). The review is based on established frameworks of physical impairment and functional limitations that have guided research in physical function in the aging population. Definitions and measures for physiologic impairments, physical performance limitations, self-reported function, and physical activity are presented. On the basis of the information presented, recommendations for incorporating routine assessment of physical function and encouragement for physical activity in clinical care are provided.

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Effect of resistance exercise during hemodialysis on physical function and quality of life: randomized controlled trial

Cited by 94 publications

References 27 publications

Effects of resistance exercise training on acyl-ghrelin and obestatin levels in hemodialysis patients

Effects of resistance exercise training on acyl-ghrelin and obestatin levels in hemodialysis patients

Intradialytic Exercise in Hemodialysis Patients: A Systematic Review and Meta-Analysis

Assessing Physical Function and Physical Activity in Patients with CKD

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