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ABSTRACTTest methods currently used by the National Institute for Occupational Safety and Health (NIOSH) are designed to assure that respirators meet a minimum level of efficacy when tested under standard laboratory protocols. For air-purifying respirators (APRs), the primary performance tests most affected by airflow rate are filter gas-life capacity, particulate filter efficiency, and respirator breathing resistances. Presently, NIOSH measures all three parameters using constant-rate airflow conditions. An analysis of the measured and estimated minute volumes contained in the literature indicated a range from about 8 to 162 L'min' for unencumbered ventilation and work activities that spanned from mild to exhaustive. The mean minute volume of the distribution was 38.5 ± 16.6 L'min-1, and the median was 33.6 L-minin. Based on an empirical relationship between minute volume and peak inspiratory flow (PIF), peak flows between 72 L'min-' and 183 L'min-1 would be expected for the mean minute volume for 38.5 L'min'. The anticipated range of PIF rates for the 9 5 dh percentile minute volume is between 182 L-min-' and 295 L-min-'. The results of this literature review suggest an increase in cyclic flow rates used for respirator certification testing should be considered to better represent ventilation rates found in the workplace. Blank EXECUTIVE SUMMARY Test methods currently used by the National Institute for Occupational Safety and Health (NIOSH) are designed to assure that all respirators of a given type will meet a minimum level of efficacy when tested under standard laboratory protocols. The relevance and adequacy of airflow rates used in respirator certification testing has been a longstanding debate. The concern is that the current test flow rates substantially underestimate real world values, implying that filters certified under existing standards may not provide adequate protection. For qualifying airpurifying respirators (APRs), the primar...