Effect of Saccharomyces boulardii and Bacillus subtilis B10 on intestinal ultrastructure modulation and mucosal immunity development mechanism in broiler chickens

Rajput, Imran Rashid; Li, L. Y.; Xu, Xingqi; Wu, Binyan; Zhang, Juan; Cui, Zhipeng; Yu, Dongdong; Li, W. F.

doi:10.3382/ps.2012-02845

Cited by 142 publications

(121 citation statements)

References 24 publications

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“…Individual strategies examined included direct-fed microbial (probiotics) and live microbial feed supplements which beneficially affect the host animal by improving its intestinal balance (Rajput et al, 2013; Salim et al, 2013); prebiotics, indigestible feed ingredients that beneficially affect the host by selectively stimulating the activity of beneficial bacteria resident in the animal tract (Patterson and Burkholder, 2003; Baurhoo et al, 2009; Samanta et al, 2013); vaccination (Desin et al, 2013) and immune-stimulation through cationic peptides and cytokines (Asif et al, 2004; Kogut et al, 2013); bacteriocins and antimicrobial peptides (Joerger, 2003; Svetoch and Stern, 2010); bacteriophages (Huff et al, 2005, 2013; Zhang et al, 2013); organic acids with antimicrobial activities; herbs, spices and other plant extracts (González-Lamothe et al, 2009); and controlled organic productions with emphasis on diet formulation and ingredient selection, cereal type and dietary protein source and level (Drew et al, 2004; O'Bryan et al, 2008). To date, none of these strategies have been systematically implemented.…”

Section: Alternatives To Antibioticsmentioning

confidence: 99%

Antibiotics in Canadian poultry productions and anticipated alternatives

2014

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The use of antibiotics in food-producing animals has significantly increased animal health by lowering mortality and the incidence of diseases. Antibiotics also have largely contributed to increase productivity of farms. However, antibiotic usage in general and relevance of non-therapeutic antibiotics (growth promoters) in feed need to be reevaluated especially because bacterial pathogens of humans and animals have developed and shared a variety of antibiotic resistance mechanisms that can easily be spread within microbial communities. In Canada, poultry production involves more than 2600 regulated chicken producers who have access to several antibiotics approved as feed additives for poultry. Feed recipes and mixtures vary greatly geographically and from one farm to another, making links between use of a specific antibiotic feed additive and production yields or selection of specific antibiotic-resistant bacteria difficult to establish. Many on-farm studies have revealed the widespread presence of antibiotic-resistant bacteria in broiler chickens. While some reports linked the presence of antibiotic-resistant organisms to the use of feed supplemented with antibiotics, no recent studies could clearly demonstrate the benefit of antimicrobial growth promoters on performance and production yields. With modern biosecurity and hygienic practices, there is a genuine concern that intensive utilization of antibiotics or use of antimicrobial growth promoters in feed might no longer be useful. Public pressure and concerns about food and environmental safety (antibiotic residues, antibiotic-resistant pathogens) have driven researchers to actively look for alternatives to antibiotics. Some of the alternatives include pre- and probiotics, organic acids and essential oils. We will describe here the properties of some bioactive molecules, like those found in cranberry, which have shown interesting polyvalent antibacterial and immuno-stimulatory activities.

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Section: Alternatives To Antibioticsmentioning

confidence: 99%

Antibiotics in Canadian poultry productions and anticipated alternatives

2014

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“…Innate immunity is a first-line defense against pathogen colonization, and recent findings confirmed that dietary B. subtilis can modulate immune response in broiler chickens (Lee et al, 2010). Another recent study showed that Bacillus -based DFM significantly induced inflammatory and anti-inflammatory cytokines in the jejunum and ileum of broiler chickens (Rajput et al, 2013). …”

Section: Introductionmentioning

confidence: 99%

Dietary Administration of Bacillus subtilis Enhances Growth Performance, Immune Response and Disease Resistance in Cherry Valley Ducks

et al. 2016

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Given the promising results of applying Bacillus subtilis (B.subtilis) as a probiotic in both humans and animals, the aim of this study was to systematically investigate the effects of B. subtilis on growth performance, immune response and disease resistance in Cherry Valley ducks. At 28 d post-hatch (dph), ducks fed a diet with B. subtilis weighed significantly more, had higher relative immune organ weights (e.g., bursa of Fabricius, thymus, and spleen), and exhibited greater villus heights, villus height to crypt depth ratios (duodenum and jejunum), and shallower crypt depths in the duodenum than controls fed a normal diet (p < 0.05). Moreover, the major pro-inflammatory factors and antiviral proteins, as measured in the thymus and the spleen, were higher at 28 dph in ducks fed probiotics than those of 14 dph. After 28 d of feeding, the ducks were challenged with Escherichia coli (E. coli) and novel duck reovirus (NDRV), and ducks fed B. subtilis achieved survival rates of 43.3 and 100%, respectively, which were significantly greater than the control group's 20 and 83.3%. Altogether, diets with B. subtilis can improve Cherry Valley ducks' growth performance, innate immune response, and resistance against E. coli and NDRV.

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“…this was also reported by ALUWONG et al (2013), who showed that nutrition plays a vital role in maintaining the pro-oxidant-antioxidant balance. Moreover, CaPCarOVa et al (2010) and RAJPUT et al, (2013) noticed that some microorganisms could help in oxidation resistance, scavenge hydroxyl radicals and increase antioxidant capacity. thus, the increased activity of all these antioxidant enzymes in the present study may be attributed to the environmental pathogens of Eimeria spp.…”

Section: Discussionmentioning

confidence: 99%