Effect of Selenium Supplementation on Lipid Peroxidation, Antioxidant Enzymes, and Lactate Levels in Rats Immediately After Acute Swimming Exercise

Akıl, Mustafa; Gürbüz, Ümit; Biçer, Mürsel; Sivrikaya, Abdullah; Moğulkoç, Rasim; Baltacı, Abdülkerim Kasım

doi:10.1007/s12011-010-8785-z

Cited by 23 publications

(13 citation statements)

References 38 publications

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“…In brain of healthy and mercury-exposed rats sodium selenite did not change MDA concentration (Agarval and Behari 2007). The similar effects were reported by Akil et al (2011a, b) who stated no effect of selenium supplementation (sodium selenite at two different doses: 6 mg/kg/day and 600 μg/kg/day) on MDA values in brain tissue and blood samples, respectively. Sodium selenite did not affect MDA concentration in cerebrum and cerebellum of suckling rats whose mothers were treated with methimazole during pregnancy and lactation.…”

Section: Discussionsupporting

confidence: 88%

Oxidant balance in brain of rats receiving different compounds of selenium

2013

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The influence of two organic selenocompounds and sodium selenite on oxidant processes in rat brain tissue was investigated. The study was performed on male Wistar rats. The animals were divided into four groups: I—control; II—administered with sodium selenite; III—provided with selenoorganic compound A of chain structure 4-(o-tolyl-)-selenosemicarbazide of 2-chlorobenzoic acid and IV—provided with selenoorganic compound B of ring structure 3-(2-chlorobenzoylamino-)-2-(o-tolylimino-)-4-methyl-4-selenazoline. Rats were treated by stomach tube at a dose of 5 × 10−4 mg of selenium/g of b.w. once a day for a period of 10 days. In brain homogenates total antioxidant status (TAS), activities of superoxide dismutase (SOD) and glutathione peroxidase (GPx), concentrations of ascorbic acid (AA) and reduced glutathione (GSH) as well as concentration of malonyl dialdehyde (MDA) were determined. TAS was insignificantly diminished in all selenium-supplemented groups versus control. SOD was not significantly influenced by administration of selenium. GPx was markedly decreased in group III versus control, whereas increased in group IV versus control and group III. Selenosemicarbazide depleted AA in well-marked way versus group II. GSH was significantly depressed in group III versus both control and group II and diminished in group IV versus group II. MDA was significantly decreased in group III versus both control and group II, whereas in group IV increased versus group III. As selenazoline A did not decrease elements of antioxidant barrier and increased GPx activity, it seems to be a promising agent for future studies concerning its possible application as a selenium supplement.

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Section: Discussionsupporting

confidence: 88%

Oxidant balance in brain of rats receiving different compounds of selenium

2013

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“…There are only a limited number of studies about how selenium, which is known to reduce oxidative damage in exercise, affects glucose metabolism, lactate levels, and tiredness in physical activity [47]. Akil et al [10] investigated the effects of selenium on lipid peroxidation and lactate levels in rats subjected to acute swimming exercise. He reported that the increase in free radical production and lactate levels due to acute swimming exercise in rats might be offset by selenium supplementation.…”

Section: Discussionmentioning

confidence: 99%

“…The increase in oxidative stress caused by exercise and the recognition of the stimulation of antioxidant activity by selenium inevitably entails a relation between selenium and exercise [10]. Selenium is also needed for normal testosterone metabolism and testicular morphology, which may explain the presence of several other selenoproteins in the male gonads [11].…”

Section: Introductionmentioning

confidence: 99%

“…Selenium is also needed for normal testosterone metabolism and testicular morphology, which may explain the presence of several other selenoproteins in the male gonads [11]. Akil et al [10] reported that the increase in free radical production and lactate levels due to acute swimming exercise in rats might be offset by selenium supplementation.…”

Section: Introductionmentioning

confidence: 99%

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Effect of Zinc and Selenium Supplementation on Serum Testosterone and Plasma Lactate in Cyclist After an Exhaustive Exercise Bout

Neek

Gaeini

Choobineh

2011

Biol Trace Elem Res

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Zinc and selenium are essential minerals and have roles for more than 300 metabolic reactions in the body. The purpose of this study was to investigate how exhaustive exercise affects testosterone levels and plasma lactate in cyclists who were supplemented with oral zinc and selenium for 4 weeks. For this reason, 32 male road cyclists were selected equally to four groups: PL group, placebo; Zn group, zinc supplement (30 mg/day); Se group, selenium supplement (200 μg/day); and Zn-Se group, zinc-selenium supplement. After treatment, free, total testosterone, and lactate levels of subjects were determined before and after exhaustive exercise. Resting total, free testosterone, and lactate levels did not differ significantly between groups, and were increased by exercise (P > 0.05). Serum total testosterone levels in Zn group were higher than in Se group after exercise (P < 0.05). Serum-free testosterone levels in the Zn group were higher than the other groups (P < 0.05).There was an insignificant difference between levels of lactate in the four groups after exercise (P > 0.05). The results showed that 4-week simultaneous and separately zinc and selenium supplementation had no significant effect on resting testosterone and lactate levels of subjects who consume a zinc and selenium sufficient diet. It might be possible that the effect of zinc supplementation on free testosterone depends on exercise.

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“…Effect of selenium supplementation (0.3 ppm) as selenomethionine (Se-Met) or sodium selenite (Se-Na) in a broiler finishing diet (35 -52 days old) on animal performance parameters: final body weight (g at 52 days old); average daily feed intake (g/d), average daily gain (g/d), conversion efficiency (g gain/g feed) during the period 35 -52 days; and weight of liver and abdominal fat (g) and as a percentage of body weight at 52 days old and carcass yield (%). increased exercise and it was show that selenium supplementation could increase the antioxidant activity in muscle reducing accumulation of lactate and free radicals [32]. Lisuka et al [33] observed a hypoglycemic effect of selenium supplementation and that might be due to the acceleration of glucose metabolism and the inhibition of glucose synthesis in the liver, suggesting a decrease in a source of precursor supply for the gluconeogenesis.…”

Section: Liver Glycogen and Lactate Contentmentioning

confidence: 99%

Dietary Organic and Inorganic Selenium on Liver Glycogen and Lactate, pHu, Color and Drip Loss of Chicken <i>Pectoralis</i> and <i>Gastrocnemius</i> Muscles

Puerto¹,

Olivero²,

Terevinto³

et al. 2016

OJAS

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The effect of selenium supplementation in finishing broiler diets on meat quality was studied. A corn soya based diet was supplemented with 0.3 ppm of Se from an organic (Seleno methionine; Se-Met) or inorganic source (sodium selenite; Se-Na) and offered to Rossmale chickens from thirty five to fifty two days old. Body weight and feed consumption were recorded during the experimental period. Immediately post sacrifice liver was removed and weight was recorded. The liver glycogen and lactate content was measured. Carcass yield and abdominal fat were determined. At 24 hours post mortem, pHu, colour L * , a * , b * , H˚, C*, and drip loss of the Pectoralis and Gastrocnemius muscles were determined. Se-Met supplementation significantly decreases daily food intake. Se-Na significantly increases liver glycogen and lactate content at 3 minutes post mortem. Se-Met and Se-Na significantly increase pHu as compared to the control diet. Also a Se-Met provoked a darker (lower L *) and a redder (higher a *) and a decreased tone (lower H˚) in Pectoralis. Se-Met and Se-Na significantly decrease the drip loss in Pectoralis and Gastrocnemius at 24 hours post mortem. We conclude that selenium supplementation decreases food intake and improves meat quality by improving colour and decreasing drip loss, likely by a modulation of reserve of glycogen in liver. The difference among the organic and inorganic sources is not clear and requires further investigation.

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Effect of Selenium Supplementation on Lipid Peroxidation, Antioxidant Enzymes, and Lactate Levels in Rats Immediately After Acute Swimming Exercise

Cited by 23 publications

References 38 publications

Oxidant balance in brain of rats receiving different compounds of selenium

Oxidant balance in brain of rats receiving different compounds of selenium

Effect of Zinc and Selenium Supplementation on Serum Testosterone and Plasma Lactate in Cyclist After an Exhaustive Exercise Bout

Dietary Organic and Inorganic Selenium on Liver Glycogen and Lactate, pHu, Color and Drip Loss of Chicken <i>Pectoralis</i> and <i>Gastrocnemius</i> Muscles

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Effect of Selenium Supplementation on Lipid Peroxidation, Antioxidant Enzymes, and Lactate Levels in Rats Immediately After Acute Swimming Exercise

Cited by 23 publications

References 38 publications

Oxidant balance in brain of rats receiving different compounds of selenium

Oxidant balance in brain of rats receiving different compounds of selenium

Effect of Zinc and Selenium Supplementation on Serum Testosterone and Plasma Lactate in Cyclist After an Exhaustive Exercise Bout

Dietary Organic and Inorganic Selenium on Liver Glycogen and Lactate, pHu, Color and Drip Loss of Chicken &lt;i&gt;Pectoralis&lt;/i&gt; and &lt;i&gt;Gastrocnemius&lt;/i&gt; Muscles

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Dietary Organic and Inorganic Selenium on Liver Glycogen and Lactate, pHu, Color and Drip Loss of Chicken <i>Pectoralis</i> and <i>Gastrocnemius</i> Muscles