Effect of sesame (<i>Sesamum indicum L</i>.) consumption on glycemic control in patients with type 2 diabetes: A systematic review and meta‐analysis of randomized controlled trials

Ramírez‐Coronel, Andrés Alexis; Alhilali, Khetam Abdalsada Ali; Ahmed, Yousif Baha’addin; Almalki, Sami G.; Karimian, Jahangir

doi:10.1002/ptr.7918

Cited by 4 publications

(3 citation statements)

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“…Moreover, findings from randomized controlled trials administering nuts as intervention arm confirm their potential effects on total and low-density lipoprotein cholesterol [ 149 ]. Concerning seeds, only a minority of studies have been conducted on commercial products, such as sesame [ 150 , 151 ], fenugreek [ 152 ], and flaxseeds [ 153 , 154 ] reporting significant effects of markers of inflammation and CVD risk factors, albeit not with univocal result [ 155 – 157 ]. These energy-rich foods are characterized by richness in essential fatty acids and fiber that may be responsible for their cholesterol-lowering properties [ 158 ].…”

Section: Underrated Aspects Of the Mediterranean Dietmentioning

confidence: 99%

Underrated aspects of a true Mediterranean diet: understanding traditional features for worldwide application of a “Planeterranean” diet

Godos,

Scazzina,

Paternò Castello

et al. 2024

J Transl Med

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Over the last decades, the Mediterranean diet gained enormous scientific, social, and commercial attention due to proven positive effects on health and undeniable taste that facilitated a widespread popularity. Researchers have investigated the role of Mediterranean-type dietary patterns on human health all around the world, reporting consistent findings concerning its benefits. However, what does truly define the Mediterranean diet? The myriad of dietary scores synthesizes the nutritional content of a Mediterranean-type diet, but a variety of aspects are generally unexplored when studying the adherence to this dietary pattern. Among dietary factors, the main characteristics of the Mediterranean diet, such as consumption of fruit and vegetables, olive oil, and cereals should be accompanied by other underrated features, such as the following: (i) specific reference to whole-grain consumption; (ii) considering the consumption of legumes, nuts, seeds, herbs and spices often untested when exploring the adherence to the Mediterranean diet; (iii) consumption of eggs and dairy products as common foods consumed in the Mediterranean region (irrespectively of the modern demonization of dietary fat intake). Another main feature of the Mediterranean diet includes (red) wine consumption, but more general patterns of alcohol intake are generally unmeasured, lacking specificity concerning the drinking occasion and intensity (i.e., alcohol drinking during meals). Among other underrated aspects, cooking methods are rather simple and yet extremely varied. Several underrated aspects are related to the quality of food consumed when the Mediterranean diet was first investigated: foods are locally produced, minimally processed, and preserved with more natural methods (i.e., fermentation), strongly connected with the territory with limited and controlled impact on the environment. Dietary habits are also associated with lifestyle behaviors, such as sleeping patterns, and social and cultural values, favoring commensality and frugality. In conclusion, it is rather reductive to consider the Mediterranean diet as just a pattern of food groups to be consumed decontextualized from the social and geographical background of Mediterranean culture. While the methodologies to study the Mediterranean diet have demonstrated to be useful up to date, a more holistic approach should be considered in future studies by considering the aforementioned underrated features and values to be potentially applied globally through the concept of a “Planeterranean” diet.

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Section: Underrated Aspects Of the Mediterranean Dietmentioning

confidence: 99%

Underrated aspects of a true Mediterranean diet: understanding traditional features for worldwide application of a “Planeterranean” diet

Godos,

Scazzina,

Paternò Castello

et al. 2024

J Transl Med

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“…In 2017, the whole world produced about 5.9 million tons of sesame seeds, with Tanzania producing the most followed by China [45]. Ramírez-Coronel et al and Sohouli et al found that sesame help in reducing FPC and HbA1c significantly in patients with T2D [46,47]. For people with certain health conditions, such as T2D and Metabolic syndrome, taking a certain amount of sesame oil or adding it to their food every day can help improve their health.…”

Section: Sesamum Indicum L (Sesame)mentioning

confidence: 99%

Paradigm of Complementary and Alternative Medicine in Type 2 Diabetes

Zaid Aljulifi

2023

Type 2 Diabetes in 2024 - From Early Suspicion to Effective Management

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Complementary and alternative medicine (CAM) is increasingly used by patients nowadays. The pooled prevalence of CAM use is about 51%. Many types of CAM have been practiced by patients with diabetes. Some of them showed promising results on blood glucose and other cardiometabolic parameters such as blood pressure, body mass, and lipid profile. This chapter explores two main types of CAM: Herbs and mind–body therapy. Different types of mind–body therapy and plants, plant extracts, and herbal substances have been utilized for an extended period and are sometimes favored by many individuals with T2D. Those practices and compounds found in these natural remedies are believed to have the potential to benefit the body in several ways, including the reduction of symptoms, alleviation of pain, and promotion of overall health. This chapter includes a summary of the findings of the available systematic reviews and meta-analyses regarding the most used medicinal herbs and body–mind therapies. In conclusion, as some of these interventions are promising, it is unclear to what extent glucose metabolism and certain substances can help mitigate complications in late-stage diabetes. Healthcare providers should be aware about them.

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“…Sesame seeds (Sesamum indicum L.) contain a multitude of phenolic compounds, which exhibit beneficial effects on human health. Phenolic components, known for their antioxidant, anti-inflammatory and hypolipidemic activities, and, specifically, sesame lignans like sesamin and sesamolin have attracted large interest regarding their nutritional benefits for humans in conditions such as atherosclerosis, hypertension, hyperlipidemia, obesity, diabetes, osteoporosis, arthritis and Alzheimer's disease [1][2][3][4][5][6][7][8]. A number of studies with sesame oil have reported a reduction in oxidative stress and an increase in vitamin E levels [9,10].…”

Section: Introductionmentioning

confidence: 99%

Effect of Fortification of Tahini with Natural Plant Origin Raw Materials on Its Bioactivity

Achilladelis,

Petsas,

Karantonis

2023

Applied Sciences

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Food fortification is a strategic approach to enhance the nutritional quality of food by incorporating bioactive compounds derived from food by-products. The objective of this study was to assess the impact on bioactivity of tahini enriched with a 4% (w/w) lyophilized microwave-ultrasound assisted extract of red grape pomace from the Limnio variety and a 6% (w/w) freeze-dried aquafaba obtained from Lemnian chickpeas of the Panagia variety. The evaluation was conducted through in vitro experiments. The samples under study were extracted by the Bligh and Dyer method and analyzed for their polyphenolic content, as well as for their content in total flavonoids. Assessment of the antioxidant capacity of the extracts was determined in vitro by the ABTS, DPPH, CUPRAC, FRAP and human blood plasma oxidation inhibition (hBPOxi) assays, while the antiplatelet activity of the extracts was determined by the Platelet Activating Factor inhibition assay (PAFi). The bioactivity of fortified tahini (LAC) was increased compared to plain tahini (Control sample). Total phenolics and total flavonoids were increased by 76% and 78%, respectively (10.7 ± 0.2 vs. 6.02 ± 0.3 and 8.5 ± 0.14 vs. 4.76 ± 0.1 μmol Trolox/g, respectively). Antioxidant activities based on ABTS, DPPH, CUPRAC, FRAP and hBPOxi were increased by 101%, 65%, 77%, 73% and 110%, respectively (52.8 ± 0.7 vs. 26.3 ± 0.4; 20.1 ± 1.6 vs. 12.2 ± 0.2; 81.9 ± 0.4 vs. 46.1 ± 2.1; 46.4 ± 4.0 vs. 26.8 ± 0.8; and 12.2 ± 0.9 vs. 5.8 ± 0.2 μmol Trolox/g, respectively), and antiplatelet activity based on PAFi was also increased by 41% (0.19 ± 0.01 vs. 0.32 ± 0.02 mg, respectively). Red grape pomace extract and aquafaba boosted tahini’s in vitro antioxidant and antiplatelet capabilities. The results indicate that the valorization of grape and chickpea processing residuals may reduce waste and improve the nutritional value of tahini. Due to its antioxidant and antiplatelet activities, fortified tahini may contribute to the prevention of chronic diseases where oxidation and thrombosis play critical roles. This study exemplifies sustainable resource use and waste reduction, as well as the importance of circular economy strategies in enhancing diets and human welfare.

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Effect of sesame (Sesamum indicum L.) consumption on glycemic control in patients with type 2 diabetes: A systematic review and meta‐analysis of randomized controlled trials

Cited by 4 publications

References 64 publications

Underrated aspects of a true Mediterranean diet: understanding traditional features for worldwide application of a “Planeterranean” diet

Underrated aspects of a true Mediterranean diet: understanding traditional features for worldwide application of a “Planeterranean” diet

Paradigm of Complementary and Alternative Medicine in Type 2 Diabetes

Effect of Fortification of Tahini with Natural Plant Origin Raw Materials on Its Bioactivity

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