Effect of signalment on the presentation of canine patients suffering from cranial cruciate ligament disease

Guthrie, James W.; Keeley, Benjamin J.; Maddock, E.; Bright, S. R.; May, Chris

doi:10.1111/j.1748-5827.2011.01202.x

Cited by 35 publications

(55 citation statements)

References 32 publications

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“…Typical management includes a 6–12 week post-surgical period of confinement and exercise restriction. Because patients may be young, 1 active, healthy, and unaccustomed to confinement, implementation of post-surgical instructions is often challenging to clients. Failure to comply with activity restriction may lead to protracted recovery or even surgical treatment failure, necessitating a second surgical procedure.…”

Section: Introductionmentioning

confidence: 99%

Use of trazodone to facilitate postsurgical confinement in dogs

Gruen¹,

Roe²,

Griffith³

et al. 2014

javma

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Objective To investigate the safety and efficacy of the oral serotonin antagonist/reuptake inhibitor trazodone hydrochloride to facilitate confinement and calming after orthopedic surgery in dogs. Design Prospective open-label trial. Animals 36 client-owned dogs. Procedures Healthy dogs were recruited when presented for pre-surgical evaluation for orthopedic procedures. Starting the day after surgery, dogs were administered trazodone (~3.5 mg/kg, per os (PO), q12h) with tramadol (4–6 mg/kg, PO, q8–12h) for pain management. After 3 days, tramadol was discontinued and trazodone was increased (~7 mg/kg, PO, q12h) and maintained for at least 4 weeks. If needed, trazodone dosage was increased to 7–10 mg/kg, PO, q8h. Clients completed electronic surveys rating their dogs’ confinement tolerance, calmness/hyperactivity level, and responses to specific provocative situations, prior to surgery and at 1, 2, 3, and 4 weeks and at the post-surgical evaluation (8–12 weeks). Results The majority of clients (~90%) reported that, when given trazodone during the 8–12 weeks following orthopedic surgery, their dogs improved moderately or extremely with regard to confinement tolerance and calmness. Trazodone was well tolerated, even in combination with non-steroidal drugs, antibiotics, and other medications; no dogs were withdrawn from the study due to adverse reactions. Client-reported median onset of action of trazodone was 31–45 minutes and median duration of action was four or more hours. Conclusions and Clinical Relevance The results suggest that oral trazodone is a safe and efficacious medication that may be used to facilitate confinement and enhance behavioral calmness of dogs during the critical recovery period following orthopedic surgery.

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Section: Introductionmentioning

confidence: 99%

Use of trazodone to facilitate postsurgical confinement in dogs

Gruen¹,

Roe²,

Griffith³

et al. 2014

javma

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“…, Guthrie et al . ). All dogs examined in this study were medium and large breeds, and thus represented dogs in which CrCL rupture occurs most frequently.…”

Section: Discussionmentioning

confidence: 97%

Effect of anatomic variation in caudal tibial plateau on the tibial plateau angle in dogs: a cadaveric study

Ocal

Sabanci

2013

J of Small Animal Practice

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“…Ethical approval for this study was granted by the RVC Ethics and Welfare Committee (reference number 2014 0120H). The VetCompass Programme collates de‐identified electronic patient record (EPR) data from primary‐care veterinary practices in the United Kingdom for epidemiological research . Participating practices can record summary diagnosis terms from an embedded standard nomenclature, the VeNom codes, at episodes of clinical care.…”

Section: Methodsmentioning

confidence: 99%

Epidemiology, clinical management, and outcomes of dogs involved in road traffic accidents in the United Kingdom (2009–2014)

Harris¹,

Brodbelt²,

Church³

et al. 2018

J Vet Emergen Crit Care

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Effect of signalment on the presentation of canine patients suffering from cranial cruciate ligament disease

Abstract: Breed affects the incidence of developing and presenting with bilateral cranial cruciate ligament disease. Breed and sex both affect the age that patients present with cranial cruciate ligament disease.

Cited by 35 publications

References 32 publications

Use of trazodone to facilitate postsurgical confinement in dogs

Use of trazodone to facilitate postsurgical confinement in dogs

Effect of anatomic variation in caudal tibial plateau on the tibial plateau angle in dogs: a cadaveric study

Epidemiology, clinical management, and outcomes of dogs involved in road traffic accidents in the United Kingdom (2009–2014)

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