Effect of Single Dose Intramuscular Methylprednisolone Injection into the Masseter Muscle on the Surgical Extraction of Impacted Lower Third Molars: a Randomized Controlled Trial

Abstract

Background

Randomized Controlled Trial to Evaluate the Efficacy of Oral Dexamethasone and Intramuscular Dexamethasone in Mandibular Third Molar Surgeries

“…The results of the same are listed in [Table/ Fig-1] [14][15][16][17][18][19][20][21][22][23][24]. Most of these studies have administered corticosteroids preoperatively whereas in our study we administered it postoperatively.…”

A Comparative Study on the Efficacy of Submucosal Injection of Dexamethasone Versus Methylprednisolone in Reducing Postoperative Sequelae After Third Molar Surgery

“…As for the decision to perform pre-emptive administration, this was done solely based on the reports by several authors who showed that pre-emptive administration was significantly better than administration performed postoperatively. 7,[22][23][24][25] The rationale behind preemptive administration is that corticosteroids should be given before the onset of the inflammatory process.…”

Efficacy of Methylprednisolone Injected into Masseter Muscle Preoperatively in Surgical Extraction of Lower Third Molars: A Randomized Placebo Controlled Triple Blind Study

“…Different administration routes have been used for these drugs in oral surgery [10]. The use of oral forms might cause gastrointestinal upset, and steroids are best taken with food [11]. Effectiveness of the oral route of administration is dependent on patient compliance, and repeated dosing is required to maintain adequate blood levels during the postoperative period.…”