Effect of size and protein environment on electrochemical properties of gold nanoparticles on carbon electrodes

Abdullin, Timur I.; Bondar, Oksana V.; Nikitina, I. I.; Bulatov, Emil; Morozov, Mikhail; Hilmutdinov, Albert K.; Салахов, М. Х.; Çulha, Mustafa

doi:10.1016/j.bioelechem.2009.06.002

Cited by 22 publications

(14 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…We did not study the adsorption of other immunogenic bacteria components such as proteins onto CNTs. However, as we demonstrated earlier, CNTs rapidly adsorb proteins on electrode surface (Abdullin et al, 2009a) probably by means of interactions with hydrophobic domains of proteins.…”

Section: Discussionmentioning

confidence: 81%

Binding and purification of plasmid DNA using multi-layered carbon nanotubes

Shakhmaeva¹,

Bulatov²,

Bondar³

et al. 2011

Journal of Biotechnology

Self Cite

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 81%

Binding and purification of plasmid DNA using multi-layered carbon nanotubes

Shakhmaeva¹,

Bulatov²,

Bondar³

et al. 2011

Journal of Biotechnology

Self Cite

View full text Add to dashboard Cite

“…31 The electrochemical surface area of the modified electrode was evaluated by the charge that passed in a reduction of the gold oxide peak using a conversion factor of μC cm -2 . [36][37][38][39][40][41] The electrochemical area of the gold nanoparticles modified screen-printed carbon electrode used in this work was determined to be 0.004 cm 2 . Figure 3 shows a cyclic voltammogram of a mercaptosuccinic acid gold nanoparticles modified Screen-printed carbon electrode prior to aluminium ion accumulation measured in a 40 mM sodium acetate buffer with 0.5 M KCI.…”

Section: Resultsmentioning

confidence: 99%

Highly Sensitive Aluminium(III) Ion Sensor Based on a Self-assembled Monolayer on a Gold Nanoparticles Modified Screen-printed Carbon Electrode

2015

View full text Add to dashboard Cite

“…AFM images were obtained using the atomic force microscope (JEOL JSPM-5200, Japan) in a dark room at 25°C. The cantilever oscillation frequency was tuned to the resonance frequency of approximately 256 kHz [23].…”

Section: Atomic Force Microscopy (Afm) Analysismentioning

confidence: 99%

Anticancer potential of nanogold conjugated toxin GNP-NN-32 from Naja naja venom

Attarde

Pandit

2020

J. Venom. Anim. Toxins incl. Trop. Dis

View full text Add to dashboard Cite

Background: Cancer is the second most common fatal disease in the world, behind cardiovascular disorders in the first place. It accounts for around 0.3 million deaths per year in India due to the lack of proper diagnostic facilities, prevention and treatment. Current therapeutic methods do not provide adequate protection and affect normal cells along with cancerous ones. Thus, there is a need for some alternative therapeutic strategy, preferably from natural products, which have been traditionally used for treatment of various diseases in the country. Methods: In this study, we have conjugated purified NN-32 toxin from Naja naja venom with gold nanoparticles and its anticancer potential was evaluated against human breast cancer cell lines. UV-Vis spectroscopy, dynamic light scattering, transmission electron microscopy, atomic force microscopy and zeta potential analysis were the techniques used for characterization of GNP-NN-32. Results: GNP-NN-32 showed dose-and time-dependent cytotoxicity against breast cancer cell lines (MCF-7 and MDA-MB-231). NN-32 and GNP-NN-32 induced apoptosis in both breast cancer cell lines. The results of CFSE cell proliferation study revealed that NN-32 and GNP-NN-32 arrested cell division in both MCF-7 and MDA-MB-231 cell lines resulting in inhibition of proliferation of these cancer cells. Conclusion: GNP-NN-32 showed an anticancer potential against human breast cancer cell lines. Analysis of detailed chemical characterization along with its cytotoxic property might help to perceive a new dimension of the anti-cancer potential of GNP-NN-32 that will enhance its biomedical function in near future.

show abstract

Effect of size and protein environment on electrochemical properties of gold nanoparticles on carbon electrodes

Cited by 22 publications

References 19 publications

Binding and purification of plasmid DNA using multi-layered carbon nanotubes

Binding and purification of plasmid DNA using multi-layered carbon nanotubes

Highly Sensitive Aluminium(III) Ion Sensor Based on a Self-assembled Monolayer on a Gold Nanoparticles Modified Screen-printed Carbon Electrode

Anticancer potential of nanogold conjugated toxin GNP-NN-32 from Naja naja venom

Contact Info

Product

Resources

About