Chayote (Sechium edule Sw.), a hairy climbing shrub, belongs to Cucurbitaceae family. It is native to mountains of Central America where it was first domesticated by Aztecs (Singh, Verma, Arya, & Muneem, 2002). In India, chow-chow is widely grown in entire NorthEastern Hill (NEH) region where it is known as isqush (Nepali), chayote (Hindi/English), is-kush, squash (Sikkim), sikot (Meghalaya), dashkush (Manipur), is-kus (Nagaland), ishkus (Darjeeling) and iskut (Mizoram). The fruits have more than eighty-six variants found in the region of Meghalaya, Mizoram and Sikkim (Rai, Sanwal, Yadav, & Phukan, 2006). It is single seeded fruit with different colours (light yellow to dark green) and different shapes (ovoid, peer, spherical, elongated). The fruit is a rich source of carbohydrates, proteins, fat, minerals and vitamins, particularly vitamin A and vitamin C (Sanwal, Yadav, Singh, & Rai, 2008). The fruits and seeds have higher antioxidant activity (Ordonez, Gomez, & Isla, 2006) and are rich in several important amino acids. Low calorific value, high dietary fibre, high potassium and very low sodium contents of fruit make it suitable for people suffering from high blood pressure and cardiovascu