Effect of Some Antibiotics on Pigmentation in Serratia marcescens

Anğ-Küçüker, Mine; Büyükbaba-Boral, Özden; Tolün, Venus; Torumkuney, D; Susever, Serdar; Anǧ, Özdem

doi:10.1016/s0934-8840(00)80001-8

Cited by 5 publications

(3 citation statements)

References 9 publications

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“…Furthermore, the colonies that grew in the presence of the cockroaches did apparently not produce the red pigment prodigiosin ( Figure 5B ), which is responsible for the characteristic red coloration of many S. marcescens strains under normal conditions ( Figure 5A ) [63] . This effect of inhibition of prodigiosin synthesis in S. marcescens has also been observed for several antibiotics [64] and the plant-derived coumarin umbelliprenin [65] .…”

Section: Discussionsupporting

confidence: 64%

Multifaceted Defense against Antagonistic Microbes in Developing Offspring of the Parasitoid Wasp Ampulex compressa (Hymenoptera, Ampulicidae)

2014

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Effective antimicrobial strategies are essential adaptations of insects to protect themselves, their offspring, and their foods from microbial pathogens and decomposers. Larvae of the emerald cockroach wasp, Ampulex compressa, sanitize their cockroach hosts, Periplaneta americana, with a cocktail of nine antimicrobials comprising mainly (R)-(-)-mellein and micromolide. The blend of these antimicrobials has broad-spectrum antimicrobial activity. Here we explore the spatio-temporal pattern of deployment of antimicrobials during the development from egg to adult as well as their physico-chemical properties to assess how these aspects may contribute to the success of the antimicrobial strategy. Using gas chromatography/mass spectrometry (GC/MS) we show that larvae start sanitizing their food as soon as they have entered their host to feed on its tissue. Subsequently, they impregnate the cockroach carcass with antimicrobials to create a hygienic substrate for cocoon spinning inside the host. Finally, the antimicrobials are incorporated into the cocoon. The antimicrobial profiles on cockroach and wasp cocoon differed markedly. While micromolide persisted on the cockroaches until emergence of the wasps, solid-phase microextraction sampling and GC/MS analysis revealed that (R)-(-)-mellein vaporized from the cockroaches and accumulated in the enclosed nest. In microbial challenge assays (R)-(-)-mellein in the headspace of parasitized cockroaches inhibited growth of entomopathogenic and opportunistic microbes (Serratia marcescens, Aspergillus sydowii, Metarhizium brunneum). We conclude that, in addition to food sanitation, A. compressa larvae enclose themselves in two defensive walls by impregnating the cocoon and the cockroach cuticle with antimicrobials. On top of that, they use vaporous (R)-(-)-mellein to sanitize the nest by fumigation. This multifaceted antimicrobial defense strategy involving the spatially and temporally coordinated deployment of several antimicrobials in solution and vapor form has apparently evolved to reliably protect the larvae themselves and their food against a broad range of antagonistic microbes.

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Section: Discussionsupporting

confidence: 64%

Multifaceted Defense against Antagonistic Microbes in Developing Offspring of the Parasitoid Wasp Ampulex compressa (Hymenoptera, Ampulicidae)

2014

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“…Prodigiosin is a secondary metabolite; and numerous factors, including biotic and abiotic factors, have been reported to affect its production in S. marcescens (Anǧ-Küçüker et al 1999;Blessing and Süssmuth 1991;Cang et al 2000;Dierstein et al 1989;Qadri and Williams 1972;Silverman and Munoz 1973;Solé et al 1994Solé et al , 1997Tsang and Feng 1983;Viñas et al 1987). Similarly, light influences prodigiosin production by S. marcescens; Ryazantseva et al (1995) reported that visible light induced phototranslation of prodigiosin and suggested that the pigmented bacterium uses prodigiosin to store visible light energy.…”

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confidence: 99%

Effects of light conditions on prodigiosin stability in the biocontrol bacterium Serratia marcescens strain B2

et al. 2004

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Serratia marcescens strain B2 is a potential biocontrol agent that produces the antibiotic pigment prodigiosin. When this strain was incubated under white or blue light conditions (Ͻ100 µmol m Ϫ2 s Ϫ1 ), prodigiosin concentration in bacterial cells decreased, but growth did not. However, red and far-red light had no effect on prodigiosin concentration in bacterial cells. Purified prodigiosin was degraded under white or blue light conditions but was not degraded under red and far-red light. Because white and blue light appeared to affect the stability of prodigiosin itself, light conditions may affect the suppressive effects of the biocontrol agent S. marcescens strain B2.

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“…Erythromycin stearate 2 grams daily in divided doses) was given for 10 days. 4,5 He was advised to improve personal hygiene in home, gym and workplace. He was observed weekly for 3 months now.…”

Section: Case Reportmentioning

confidence: 99%

Ephydrosis tincta - “Think Pink, but don’t wear it” – An interesting case report

Rajagopalan

2023

IJCED

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Chromhidrosis or ephydrosis tincta is a rare sweat gland disorder with a characteristic presentation of the secretion of colored sweat, first reported by Yonge in 1709. This condition can be subdivided into apocrine chromhidrosis, eccrine chromhidrosis and pseudo-eccrine chromhidrosis. Treatment depends on type and cause. Pseudochromhidrosis is the change of color of normal eccrine sweat on the skin by surface compounds, molecules or chromogenic bacteria. Here we report a case of pink coloured sweat and marked staining of clothes and under garments in a previously asymptomatic young male soft wear engineer without any underlying co morbidities that affected his quality of life. He responded well to oral antibiotics. Though unharmful, it lead to social embarrassment and psychological issues.

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Effect of Some Antibiotics on Pigmentation in Serratia marcescens

Cited by 5 publications

References 9 publications

Multifaceted Defense against Antagonistic Microbes in Developing Offspring of the Parasitoid Wasp Ampulex compressa (Hymenoptera, Ampulicidae)

Multifaceted Defense against Antagonistic Microbes in Developing Offspring of the Parasitoid Wasp Ampulex compressa (Hymenoptera, Ampulicidae)

Effects of light conditions on prodigiosin stability in the biocontrol bacterium Serratia marcescens strain B2

Ephydrosis tincta - “Think Pink, but don’t wear it” – An interesting case report

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