The hydrogel-based sensors suffer from poor stability and low sensitivity, severely limiting their further development. It is still “a black box” to understand the effect of the encapsulation as well as the electrode on the performance of the hydrogel-based sensors. To address these problems, we prepared an adhesive hydrogel that could robustly adhere to Ecoflex (adhesive strength is 4.7 kPa) as an encapsulation layer and proposed a rational encapsulation model that fully encapsulated the hydrogel within Ecoflex. Owing to the excellent barrier and resilience of Ecoflex, the encapsulated hydrogel-based sensor can still work normally after 30 days, displaying excellent long-term stability. In addition, we performed theoretical and simulation analyses on the contact state between the hydrogel and the electrode. It was surprising to find that the contact state significantly affects the sensitivity of the hydrogel sensors (the maximum difference in sensitivity was 333.6%), indicating that the reasonable design of the encapsulation and electrode are indispensable parts for fabricating successful hydrogel sensors. Therefore, we paved the way for a novel insight to optimize the properties of the hydrogel sensors, which is greatly favorable to developing hydrogel-based sensors to be applied in various fields.