Effect of spinal anterior root stimulation and sacral deafferentation on bladder and sexual dysfunction in spinal cord injury

Zaer, Hamed; Rasmussen, Mikkel Mylius; Zepke, F; Bodin, C.; Domurath, B.; Kutzenberger, J.

doi:10.1007/s00701-018-3557-1

Cited by 9 publications

(9 citation statements)

References 17 publications

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“…It could permit urinary and sexual function recovery in patients with complete or incomplete S2–S4 lesions; however, only a few cases were described [ 52 ]. Sacral anterior root stimulation (SARS) and later sacral deafferentation (SDAF) introduced by Brindley [ 53 ] primarily for neurogenic bladder dysfunction in SCI individuals could be an option for neurogenic sexual dysfunction management [ 54 ]. Zaer et al in a recent study with 287 patients [ 54 ] described a compensation of erection reflex due to electrostimulation reflex erection in 30% of male patients after SARS-SDAF procedures.…”

Section: Discussionmentioning

confidence: 99%

“…Sacral anterior root stimulation (SARS) and later sacral deafferentation (SDAF) introduced by Brindley [ 53 ] primarily for neurogenic bladder dysfunction in SCI individuals could be an option for neurogenic sexual dysfunction management [ 54 ]. Zaer et al in a recent study with 287 patients [ 54 ] described a compensation of erection reflex due to electrostimulation reflex erection in 30% of male patients after SARS-SDAF procedures. On the other hand, no significant differences were observed in female patients corroborating the theory that the women’s sexual cycle is more controlled by mental excitements than physical symptoms [ 54 ].…”

Section: Discussionmentioning

confidence: 99%

“…Zaer et al in a recent study with 287 patients [ 54 ] described a compensation of erection reflex due to electrostimulation reflex erection in 30% of male patients after SARS-SDAF procedures. On the other hand, no significant differences were observed in female patients corroborating the theory that the women’s sexual cycle is more controlled by mental excitements than physical symptoms [ 54 ].…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Epidemiology and aetiology of male and female sexual dysfunctions related to pelvic ring injuries: a systematic review

Rovere

Perna

Meccariello³

et al. 2021

International Orthopaedics (SICOT)

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Introduction Pelvic ring injuries, frequently caused by high energy trauma, are associated with high rates of morbidity and mortality (5–33%), often due to significant blood loss and disruption of the lumbosacral plexus, genitourinary system, and gastrointestinal system. The aim of the present study is to perform a systematic literature review on male and female sexual dysfunctions related to traumatic lesions of the pelvic ring. Methods Scopus, Cochrane Library MEDLINE via PubMed, and Embase were searched using the keywords: “Pelvic fracture,” “Pelvic Ring Fracture,” “Pelvic Ring Trauma,” “Pelvic Ring injury,” “Sexual dysfunction,” “Erectile dysfunction,” “dyspareunia,” and their MeSH terms in any possible combination. The following questions were formulated according to the PICO (population (P), intervention (I), comparison (C), and outcome (O)) scheme: Do patients suffering from pelvic fracture (P) report worse clinical outcomes (C), in terms of sexual function (O), when urological injury occurs (I)? Is the sexual function (O) influenced by the type of fracture (I)? Results After screening 268 articles by title and abstract, 77 were considered eligible for the full-text analysis. Finally 17 studies that met inclusion criteria were included in the review. Overall, 1364 patients (902 males and 462 females, M/F ratio: 1.9) suffering from pelvic fractures were collected. Discussion Pelvic fractures represent challenging entities, often concomitant with systemic injuries and subsequent morbidity. Anatomical consideration, etiology, correlation between sexual dysfunction and genitourinary lesions, or pelvic fracture type were investigated. Conclusion There are evidences in the literature that the gravity and frequency of SD are related with the pelvic ring fracture type. In fact, patients with APC, VS (according Young-Burgess), or C (according Tile) fracture pattern reported higher incidence and gravity of SD. Only a week association could be found between GUI and incidence and gravity of SD, and relationship between surgical treatment and SD. Electrophysiological tests should be routinely used in patient suffering from SD after pelvic ring injuries.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Epidemiology and aetiology of male and female sexual dysfunctions related to pelvic ring injuries: a systematic review

Rovere

Perna

Meccariello³

et al. 2021

International Orthopaedics (SICOT)

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“…A different approach was adopted by Zaer et al [47], who evaluated the effects of sacral anterior root stimulation with sacral deafferentation (SARS-SDAF) on neurogenic bladder and NSD in a large SCI population. The results did not show significant differences before and after SARS-SDAF surgery regarding the capability of genital swelling with or without stimulation, orgasm, usage of sexual aids or medicines, and the capacity to have sexual intercourse.…”

Section: Female Sdmentioning

confidence: 99%

Neurogenic Sexual Dysfunction Treatment: A Systematic Review

Popolo

Cito

Lepri

et al. 2020

European Urology Focus

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“…Other molecules have also been implicated in the response of SCS to the patient's condition, including activation of the cholinergic system with release of acetylcholine, adenosine, serotonin, and norepinephrine [1]. Although the effect of SCS after spinal cord injury has been recently evaluated regarding colorectal and bladder functions in animals [3] and patients [4][5][6], its effect on the neurovegetative system in patients submitted to conventional SCS implantation after refractory neuropathic pain or Failed Back Pain Syndrome has not been addressed to date.…”

Section: Introductionmentioning

confidence: 99%

Spinal Cord Stimulation for Refractary Neuropathic Pain and Its Action on the Neurovegetative Systems

Pedrão¹,

Lauretti²,

Matias³

et al. 2019

JBiSE

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BACKGROUND: Spinal Cord Stimulation (SCS) has been used for chronic refractory pain, however its effectivity on neurovegetative systems has not been evaluated to data. OBJECTIVES: The study was conducted to evaluate the effect of SCS in patients suffering from refractory neuropathic pain, related to analgesia, quality of life and neurovegetative actions on the digestive and urinary tracts. Fifteen patients acted as their own control related to all evaluations. P < 0.05 was considered significantly. RESULTS: 13 patients completed the study. The incidence of indication was 6% in our Center for Pain Treatment in the Teaching Hospital. The SCS improved quality of life, bowel transit and urinary function, as improved overall analgesia and decreased daily rescue analgesic (p < 0.001). CONCLUSIONS: In accordance with literature, the incidence of complications was 20%, and SCS improved analgesia and quality of life. In addition, patients also referred to improved bowel activity and urinary function.

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Effect of spinal anterior root stimulation and sacral deafferentation on bladder and sexual dysfunction in spinal cord injury

Abstract: The SARS-SDAF is a beneficial multi-potential treatment method with simultaneous positive effect on multi-organ dysfunction among SCI subjects.

Cited by 9 publications

References 17 publications

Epidemiology and aetiology of male and female sexual dysfunctions related to pelvic ring injuries: a systematic review

Epidemiology and aetiology of male and female sexual dysfunctions related to pelvic ring injuries: a systematic review

Neurogenic Sexual Dysfunction Treatment: A Systematic Review

Spinal Cord Stimulation for Refractary Neuropathic Pain and Its Action on the Neurovegetative Systems

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