Effect of spinal cord stimulation on myocardial blood flow assessed by positron emission tomography in patients with refractory angina pectoris

Hautvast, Raymond W.M.; Blanksma, PK; DeJongste, Mike J. L.; Pruim, Jan; Wall, Ernst E. van der; Vaalburg, W; Lie, Ki

doi:10.1016/s0002-9149(97)89338-1

Cited by 154 publications

(82 citation statements)

References 21 publications

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“…In a positron emission tomography study, a redistribution of myocardial flow in favor of ischemic parts of the myocardium has been demonstrated as a long-term effect of spinal cord stimulation, both at rest and after pharmacologic stress induction. 44 Nienke et al 45 conducted a prospective study on quality of life changes in patients with refractory angina pectoris implanted with SCS. They found that both the pain and the health aspects of quality of life improved significantly after 3 months of SCS.…”

Section: Anginamentioning

confidence: 99%

“…There may be homogenization of myocardial blood perfusion with SCS, and that this reduces myocardial ischemia. 44,58 Another study has demonstrated that SCS improved heart muscle lactate metabolism and oxygen demand and blood flow in the coronary sinus. 59 Other studies show that SCS does not affect variability in heart rate or cardiac arrhythmias.…”

Section: Anginamentioning

confidence: 99%

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Spinal Cord Stimulation: An Update

2008

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Summary:Spinal cord stimulation has been used in the treatment of many chronic pain disorders since 1967. In this update, the indications for spinal cord stimulation are reviewed with attention to recent publications. A focused review of the literature on abdominal and visceral pain syndromes is also provided. Furthermore, the technology has evolved from the use of monopolar electrodes to complex electrode arrays. Similarly, the power source has changed from a radio frequency-driven system to a rechargeable impulse generator. These topics are covered, along with a short discussion of implant technique. Finally, we include a review of complications of such therapy. SCS as a technology and therapy continues to evolve.

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Section: Anginamentioning

confidence: 99%

Section: Anginamentioning

confidence: 99%

Spinal Cord Stimulation: An Update

2008

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“…In a positron emission tomography (PET) study by Hautvast, 64 it was found that after a 6 week period of stimulation, the total cardiac¯ow remained unchanged, but a redistribution of this¯ow was found in favour of the ischemic regions. Just recently the results of a study of Mannheimer were published.…”

Section: Ischemic Painmentioning

confidence: 99%

Spinal cord stimulation in chronic pain syndromes

Vaarwerk

Staal²

1998

Spinal Cord

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Spinal cord stimulation (SCS) has been used for more than 30 years now, and although it has shown to be e ective under certain well-described conditions of chronic pain, conclusive evidence on its e ectiveness is still sparse.There is a need for more prospective and methodological good studies, in order to prove SCS e cacy for new or still questionable indications and to reveal prognostic factors for successful application. Especially at this moment, when governments are trying to control and reduce their health care expenses, studies on the cost-e ectiveness of SCS are important.In contrast to the early years when SCS was applied by independent physicians exploring the ®eld of neurostimulation, the importance of information exchange and coordination of studies has now been recognized. Recent technical improvements of SCS devices may positively in¯uence clinical outcome.

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“…52 ). SCS may influence function of vital organs, positron--emiting tomography (PET) showed increased perfusion of nociceptive brain areas 53 and homogenization of myocardial perfusion ("inverse steal phenomenon") in patients with RAP who had spinal cord stimulator inserted 54 . Norssell et al reported decreased turnover and re-uptake of norepinephrine in patients treated with SCS which may support the hypothesis of total reduction in an adrenergic activity due to SCS (ref.…”

Section: Results Of Non-randomized Trialsmentioning

confidence: 99%

Interventional treatment of pain in refractory angina. A review

Dobias¹,

Michálek²,

Neužil³

et al. 2014

Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub

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Background. Refractory angina is characterized by repeated attacks of chest pain in patients on maximal anti-anginal pharmacotherapy, with a professional conscensus that further surgical or radiological revascularization would be futile. Refractory angina is a serious but relatively uncommon health problem, with a reported incidence of approximately 30 patients per million people/year. In this condition simply treating the associated pain alone is important as this can improve exercise tolerance and quality of life.Methods. An extensive literature search using five different medical databases was performed and from this, eightythree papers were considered appropriate to include within this review. Results and Conclusion. Available literature highlights several methods of interventional pain treatment, including spinal cord stimulation and video-assisted upper thoracic sympathectomy which can provide good analgesia whilst improving physical activities and quality of life. The positive effect of spinal cord stimulation on the intensity of pain and quality of life has been confirmed in nine randomized controlled trials. Other potential treatment methods include stellate ganglion blocks, insertion of thoracic epidural or spinal catheters and transcutaneous electrical nerve stimulation. These approaches however appear more useful for diagnostic purposes and perhaps as short-term treatment measures.

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Effect of spinal cord stimulation on myocardial blood flow assessed by positron emission tomography in patients with refractory angina pectoris

Cited by 154 publications

References 21 publications

Spinal Cord Stimulation: An Update

Spinal Cord Stimulation: An Update

Spinal cord stimulation in chronic pain syndromes

Interventional treatment of pain in refractory angina. A review

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