Effect of steroid‐releasing sinus implants on postoperative medical and surgical interventions: an efficacy meta‐analysis

Abstract

Early postoperative healing is a predictor of longer-term success after sinus surgery. Evaluation of postoperative outcomes by a blinded independent panel demonstrates that steroid-releasing implants that provide a sustained release of corticosteroid improve surgical outcomes by reducing frank polyp formation, sinus adhesions, and middle turbinate lateralization. Steroid-releasing implants reduce the need for surgical intervention, and the need for oral steroid treatment.

International Consensus Statement on Allergy and Rhinology: Rhinosinusitis

“…1307,1317,1318 A meta-analysis combined the results from the 2 RCTs to demonstrate statistically significant reductions in the need for postoperative intervention, oral corticosteroid usage, polyposis, and adhesions. 1319 An economic evaluation also demonstrated that Propel TM is cost-effective in decreasing postoperative intervention. 1320 Concerns raised regarding the data to date have included the lack of a nonstented arm in these studies, which might show that the stenting material without the corticosteroid is proinflammatory.…”

Instrumentation in Frontal Sinus Surgery

“…Three prospective, randomized, controlled trials and one meta-analysis have demonstrated the effectiveness of steroid-eluting stents when placed in the ethmoid sinus. [6][7][8][9] Smaller implants could prove useful in maintaining frontal recess patency; however, this has not been extensively studied. Fig.…”

Overview of the Medical Management of Chronic Rhinosinusitis

“…This implant is bioabsorbable and lasts approximately 30 days if left in place. A recent meta-analysis by Han et al pooled data from two previous studies [ 39 ]. A total of 143 patients at 11 centers were evaluated.…”